Mammalian SRP receptor switches the Sec61 translocase from Sec62 to SRP-dependent translocation (Q36392449)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26634806%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Mammalian SRP receptor switches the Sec61 translocase from Sec62 to SRP-dependent translocation (English)

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1 March 2020

4

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1 March 2020

Bhalchandra Jadhav

1

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1 March 2020

Michael McKenna

2

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1 March 2020

Martin R Pool

6

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1 March 2020

author name string

Nicholas Johnson

3

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1 March 2020

Irmgard Sinning

5

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1 March 2020

language of work or name

English

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publication date

4 December 2015

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1 March 2020

published in

Nature Communications

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1 March 2020

volume

6

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1 March 2020

page(s)

10133

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Creative Commons Attribution 4.0 International

1 March 2020

copyright license

start time

1 December 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Cotranslational stabilization of Sec62/63 within the ER Sec61 translocon is controlled by distinct substrate-driven translocation events

30 September 2017

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Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution

30 September 2017

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The signal sequence influences post-translational ER translocation at distinct stages

30 September 2017

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Co-translational targeting and translocation of proteins to the endoplasmic reticulum.

30 September 2017

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SecYEG activates GTPases to drive the completion of cotranslational protein targeting

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Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation

30 September 2017

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TRC40 can deliver short secretory proteins to the Sec61 translocon

30 September 2017

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Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells

30 September 2017

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Mechanisms of Sec61/SecY-mediated protein translocation across membranes

30 September 2017

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A calmodulin-dependent translocation pathway for small secretory proteins

30 September 2017

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Tail-anchored membrane protein insertion into the endoplasmic reticulum

30 September 2017

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Lipids Trigger a Conformational Switch That Regulates Signal Recognition Particle (SRP)-mediated Protein Targeting

30 September 2017

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Structural Studies and the Assembly of the Heptameric Post-translational Translocon Complex

30 September 2017

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FlhA provides the adaptor for coordinated delivery of late flagella building blocks to the type III secretion system

30 September 2017

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Evolutionary gain of function for the ER membrane protein Sec62 from yeast to humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Following the signal sequence from ribosomal tunnel exit to signal recognition particle

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Membrane binding of the bacterial signal recognition particle receptor involves two distinct binding sites

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Ribosome binding to and dissociation from translocation sites of the endoplasmic reticulum membrane

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Transmembrane topogenesis of a tail-anchored protein is modulated by membrane lipid composition

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Protein production by auto-induction in high density shaking cultures

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Coordinated activation of Hsp70 chaperones

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Dual recognition of the ribosome and the signal recognition particle by the SRP receptor during protein targeting to the endoplasmic reticulum

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Distinct modes of signal recognition particle interaction with the ribosome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

SRbeta coordinates signal sequence release from SRP with ribosome binding to the translocon

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Sec63p and Kar2p are required for the translocation of SRP-dependent precursors into the yeast endoplasmic reticulum in vivo

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Homologs of the yeast Sec complex subunits Sec62p and Sec63p are abundant proteins in dog pancreas microsomes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Expression profiling of pancreatic beta cells: glucose regulation of secretory and metabolic pathway genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Mammalian Sec61 is associated with Sec62 and Sec63

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Evolutionarily conserved binding of ribosomes to the translocation channel via the large ribosomal RNA.

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

The ribosome regulates the GTPase of the beta-subunit of the signal recognition particle receptor

30 September 2017

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BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

The beta subunit of the Sec61 complex facilitates cotranslational protein transport and interacts with the signal peptidase during translocation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Signal sequences specify the targeting route to the endoplasmic reticulum membrane

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane

30 September 2017

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30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor

30 September 2017

1 reference

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Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle

30 September 2017

1 reference

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A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Elongation arrest is not a prerequisite for secretory protein translocation across the microsomal membrane

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Requirement of GTP Hydrolysis for Dissociation of the Signal Recognition Particle from Its Receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

The C-terminal regions of YidC from Rhodopirellula baltica and Oceanicaulis alexandrii bind to ribosomes and partially substitute for SRP receptor function in Escherichia coli

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Sequential checkpoints govern substrate selection during cotranslational protein targeting

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Escherichia coli signal recognition particle receptor FtsY contains an essential and autonomous membrane-binding amphipathic helix.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

70K heat shock related proteins stimulate protein translocation into microsomes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

A large presecretory protein translocates both cotranslationally, using signal recognition particle and ribosome, and post-translationally, without these ribonucleoparticles, when synthesized in the presence of mammalian microsomes.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Longin and GAF domains: structural evolution and adaptation to the subcellular trafficking machinery

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

SIMIBI twins in protein targeting and localization

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Screening of fusion partners for high yield expression and purification of bioactive viscotoxins

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

A precursor-specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

The structure of the mammalian signal recognition particle (SRP) receptor as prototype for the interaction of small GTPases with Longin domains

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

Preparation of microsomal membranes for cotranslational protein translocation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686813

The signal sequence of nascent preprolactin interacts with the 54K polypeptide of the signal recognition particle

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS10133

Genetic control of antibody response to bovine rhodopsin in mice: epitope mapping of rhodopsin structure

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26634806

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of Sec61alpha in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26634806

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Site-specific photocross-linking reveals that Sec61p and TRAM contact different regions of a membrane-inserted signal sequence

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26634806

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS10133

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26634806%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26634806%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

26634806

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26634806%20AND%20SRC:MED&resulttype=core&format=json