Vascular Na+/Ca2+ exchanger: implications for the pathogenesis and therapy of salt-dependent hypertension (Q36391660)

13 August 2017

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title

Vascular Na+/Ca2+ exchanger: implications for the pathogenesis and therapy of salt-dependent hypertension (English)

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13 August 2017

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Takahiro Iwamoto

1

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13 August 2017

1 March 2006

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American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

13 August 2017

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13 August 2017

290

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13 August 2017

R536-45

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13 August 2017

3

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Ouabain augments Ca(2+) transients in arterial smooth muscle without raising cytosolic Na(+).

13 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Effects of SEA0400 on mutant NCX1.1 Na+-Ca2+ exchangers with altered ionic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Influence of Na+ gradient on Ca2+ transients and contraction in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Calcium-dependent regulation of calcium efflux by the cardiac sodium/calcium exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

The alpha2-isoform of Na-K-ATPase mediates ouabain-induced hypertension in mice and increased vascular contractility in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Sodium and calcium interactions in vascular smooth muscle cells of the rabbit ear artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Intersalt revisited: further analyses of 24 hour sodium excretion and blood pressure within and across populations. Intersalt Cooperative Research Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Interaction of the Na+-K+ pump and Na+-Ca2+ exchange via [Na+]i in a restricted space of guinea-pig ventricular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Blood pressure control--special role of the kidneys and body fluids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Role of dietary salt in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Identification and characterization of a ouabain-like compound from human plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Endogenous ouabain, sodium balance and blood pressure: a review and a hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Regulation of cardiac Na+,Ca2+ exchange and KATP potassium channels by PIP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

The exchanger inhibitory peptide region-dependent inhibition of Na+/Ca2+ exchange by SN-6 [2-[4-(4-nitrobenzyloxy)benzyl]thiazolidine-4-carboxylic acid ethyl ester], a novel benzyloxyphenyl derivative

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Molecular determinants of Na+/Ca2+ exchange (NCX1) inhibition by SEA0400.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Unique topology of the internal repeats in the cardiac Na+/Ca2+ exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Phosphorylation-dependent regulation of cardiac Na+/Ca2+ exchanger via protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Subtle renal injury is likely a common mechanism for salt-sensitive essential hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Distinct distribution of different Na+ pump alpha subunit isoforms in plasmalemma. Physiological implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Direction-independent block of bi-directional Na+/Ca2+ exchange current by KB-R7943 in guinea-pig cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Synthesis and structure-activity relationships of benzyloxyphenyl derivatives as a novel class of NCX inhibitors: effects on heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Inhibitory profile of SEA0400 [2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline] assessed on the cardiac Na+-Ca2+ exchanger, NCX1.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Molecular mechanisms of human hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Differing cardioprotective efficacy of the Na+/Ca2+ exchanger inhibitors SEA0400 and KB-R7943.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Left ventricular mass, stroke volume, and ouabain-like factor in essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Regulation of cardiac Na(+)-Ca2+ exchanger by the endogenous XIP region

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Regulation of the cardiac Na(+)-Ca2+ exchanger by Ca2+. Mutational analysis of the Ca(2+)-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Effects of interstrain renal transplantation on NaCl-induced hypertension in Dahl rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

A new topological model of the cardiac sarcolemmal Na+-Ca2+ exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Mutational analysis of the alpha-1 repeat of the cardiac Na(+)-Ca2+ exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Na?Ca exchange and tension development in guinea-pig aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

The novel Na(+)/Ca(2+) exchange inhibitor KB-R7943 also blocks native and expressed neuronal nicotinic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Lessons from rat models of hypertension: from Goldblatt to genetic engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Organellar junctions promote targeted Ca2+ signaling in smooth muscle: why two membranes are better than one.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Helix packing of functionally important regions of the cardiac Na(+)-Ca(2+) exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Role of serotonin3 receptors in the nucleus tractus solitarii on the carotid chemoreflex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

The sodium/calcium exchanger family?SLC8

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Knockout mice for pharmacological screening: testing the specificity of Na+-Ca2+ exchange inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Endogenous cardiac glycosides, a new class of steroid hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Sodium/Calcium Exchanger (NCX1) Macromolecular Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Cardiac Na(+)-Ca(2+) exchange: molecular and pharmacological aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Blockade of NMDA channels in acutely isolated rat hippocampal neurons by the Na+/Ca2+ exchange inhibitor KB-R7943.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Endogenous digitalislike factor: an update.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Protective effects of SEA0400, a novel and selective inhibitor of the Na+/Ca2+ exchanger, on myocardial ischemia-reperfusion injuries

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Effect of SEA0400, a novel inhibitor of sodium-calcium exchanger, on myocardial ionic currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

A novel antagonist, No. 7943, of the Na+/Ca2+ exchange current in guinea-pig cardiac ventricular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Salt sensitivity of blood pressure in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

A circulating inhibitor of (Na+ + K+) ATPase associated with essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

Coupling of the Na+/Ca2+exchanger, Na+/K+ pump and sarcoplasmic reticulum in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00592.2005

10.1152/AJPREGU.00592.2005

21 January 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference

PubMed ID

16467501