Orexin/hypocretin (Orx/Hcrt) transmission and drug-seeking behavior: is the paraventricular nucleus of the thalamus (PVT) part of the drug seeking circuitry? (Q36386187)

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English	Orexin/hypocretin (Orx/Hcrt) transmission and drug-seeking behavior: is the paraventricular nucleus of the thalamus (PVT) part of the drug seeking circuitry?	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

Orexin/hypocretin (Orx/Hcrt) transmission and drug-seeking behavior: is the paraventricular nucleus of the thalamus (PVT) part of the drug seeking circuitry? (English)

1 reference

Europe PubMed Central

13 August 2017

author name string

Rémi Martin-Fardon

1

1 reference

Europe PubMed Central

13 August 2017

Benjamin Boutrel

2

1 reference

Europe PubMed Central

13 August 2017

publication date

9 November 2012

1 reference

Europe PubMed Central

13 August 2017

Frontiers in Behavioral Neuroscience

1 reference

Europe PubMed Central

13 August 2017

6

1 reference

Europe PubMed Central

13 August 2017

75

1 reference

Europe PubMed Central

13 August 2017

Hypocretin/orexin regulation of dopamine signaling: implications for reward and reinforcement mechanisms

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30 September 2017

A septal-hypothalamic pathway drives orexin neurons, which is necessary for conditioned cocaine preference

1 reference

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30 September 2017

Drug wanting: behavioral sensitization and relapse to drug-seeking behavior

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30 September 2017

Orexin receptors: pharmacology and therapeutic opportunities

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30 September 2017

Discrete cue-conditioned alcohol-seeking after protracted abstinence: pattern of neural activation and involvement of orexin₁ receptors

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30 September 2017

A role for hypocretin/orexin in motivation.

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30 September 2017

Cocaine- and amphetamine-regulated transcript (CART) signaling within the paraventricular thalamus modulates cocaine-seeking behaviour

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

30 September 2017

Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: factor in the transition to dependence

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30 September 2017

Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence

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30 September 2017

Hypocretin/orexin and energy expenditure.

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30 September 2017

The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system

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30 September 2017

Role of innate and drug-induced dysregulation of brain stress and arousal systems in addiction: Focus on corticotropin-releasing factor, nociceptin/orphanin FQ, and orexin/hypocretin

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30 September 2017

The role of hypocretin in driving arousal and goal-oriented behaviors.

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30 September 2017

Orexin A/hypocretin-1 selectively promotes motivation for positive reinforcers

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30 September 2017

Phasic dopamine release in appetitive behaviors and drug addiction

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

30 September 2017

Orexin/hypocretin is necessary for context-driven cocaine-seeking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

30 September 2017

N-Acetylcysteine reverses cocaine-induced metaplasticity

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30 September 2017

Paraventricular thalamic nucleus: subcortical connections and innervation by serotonin, orexin, and corticotropin-releasing hormone in macaque monkeys

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30 September 2017

Insular hypocretin transmission regulates nicotine reward

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

30 September 2017

Activation of orexin/hypocretin projections to basal forebrain and paraventricular thalamus by acute nicotine

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30 September 2017

Role of orexin/hypocretin and CRF in the formation of drug-dependent synaptic plasticity in the mesolimbic system.

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30 September 2017

Cocaine but not natural reward self-administration nor passive cocaine infusion produces persistent LTP in the VTA.

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30 September 2017

Cocaine seeking habits depend upon dopamine-dependent serial connectivity linking the ventral with the dorsal striatum

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30 September 2017

Drug addiction as a pathology of staged neuroplasticity

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30 September 2017

Arousal and reward: a dichotomy in orexin function

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

30 September 2017

The orexin system regulates alcohol-seeking in rats

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30 September 2017

Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

30 September 2017

Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

30 September 2017

A proposed hypothalamic-thalamic-striatal axis for the integration of energy balance, arousal, and food reward

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30 September 2017

The neural basis of addiction: a pathology of motivation and choice

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

30 September 2017

Neurobiology of craving, conditioned reward and relapse

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30 September 2017

Brain substrates for increased drug seeking during protracted withdrawal

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30 September 2017

Brain imaging studies in human addicts

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30 September 2017

Overlapping distributions of orexin/hypocretin- and dopamine-beta-hydroxylase immunoreactive fibers in rat brain regions mediating arousal, motivation, and stress

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30 September 2017

Lateral hypothalamic neuropeptides in reward and drug addiction

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30 September 2017

Distinct recognition of OX1 and OX2 receptors by orexin peptides.

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30 September 2017

Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex

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30 September 2017

The role of hypocretins (orexins) in sleep regulation and narcolepsy.

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30 September 2017

Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex

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30 September 2017

The hypocretins: setting the arousal threshold

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30 September 2017

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30 September 2017

Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice

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30 September 2017

Neural substrates of conditioned-cued relapse to drug-seeking behavior

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30 September 2017

Craving for alcohol and drugs in animals and humans: biology and behavior

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30 September 2017

To eat or to sleep? Orexin in the regulation of feeding and wakefulness

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30 September 2017

Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation

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30 September 2017

Neurons containing hypocretin (orexin) project to multiple neuronal systems

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30 September 2017

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

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30 September 2017

Addiction is a brain disease, and it matters

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30 September 2017

N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl urea (SB334867), a hypocretin receptor-1 antagonist, preferentially prevents ethanol seeking: comparison with natural reward seeking

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30 September 2017

Changes in emotional behavior produced by orexin microinjections in the paraventricular nucleus of the thalamus.

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28 June 2018

The paraventricular nucleus of the thalamus alters rhythms in core temperature and energy balance in a state-dependent manner

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28 June 2018

The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

28 June 2018

Conditioning factors in drug abuse: can they explain compulsion?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

28 June 2018

Neuroanatomical basis for facilitation of hypothalamic-pituitary-adrenal responses to a novel stressor after chronic stress

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28 June 2018

Convergent inputs from electrically and topographically distinct orexin cells to locus coeruleus and ventral tegmental area.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Orexin signaling in the paraventricular thalamic nucleus modulates mesolimbic dopamine and hedonic feeding in the rat.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Sources of inputs to the anterior and posterior aspects of the paraventricular nucleus of the thalamus.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

The orexin₁ receptor antagonist SB-334867 dissociates the motivational properties of alcohol and sucrose in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Medial dorsal hypothalamus mediates the inhibition of reward seeking after extinction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Orexins in the midline thalamus are involved in the expression of conditioned place aversion to morphine withdrawal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Orexins in the paraventricular nucleus of the thalamus mediate anxiety-like responses in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Paraventricular thalamus mediates context-induced reinstatement (renewal) of extinguished reward seeking.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Inhibition of orexin-1/hypocretin-1 receptors inhibits yohimbine-induced reinstatement of ethanol and sucrose seeking in Long-Evans rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Rats with extended access to cocaine exhibit increased stress reactivity and sensitivity to the anxiolytic-like effects of the mGluR 2/3 agonist LY379268 during abstinence

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Stimuli linked to ethanol availability activate hypothalamic CART and orexin neurons in a reinstatement model of relapse.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Innervation of the paraventricular nucleus of the thalamus from cocaine- and amphetamine-regulated transcript (CART) containing neurons of the hypothalamus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

The paraventricular nucleus of the thalamus as an interface between the orexin and CART peptides and the shell of the nucleus accumbens.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

A role for lateral hypothalamic orexin neurons in reward seeking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Effects of orexins/hypocretins on neuronal activity in the paraventricular nucleus of the thalamus in rats in vitro.

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21 September 2018

Involvement of thalamic paraventricular nucleus in the anticipatory reaction under food restriction in the rat.

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21 September 2018

Dopamine release in the dorsal striatum during cocaine-seeking behavior under the control of a drug-associated cue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

A selective orexin-1 receptor antagonist reduces food consumption in male and female rats.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

Myths about the treatment of addiction.

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21 September 2018

Relationship of thalamic basal forebrain projection neurons to the peptidergic innervation of the midline thalamus

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494007

21 September 2018

The intralaminar and midline nuclei of the thalamus. Anatomical and functional evidence for participation in processes of arousal and awareness

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https://pubmed.ncbi.nlm.nih.gov/23162448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuropsychological basis of addictive behaviour

1 reference

https://pubmed.ncbi.nlm.nih.gov/23162448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response

1 reference

https://pubmed.ncbi.nlm.nih.gov/23162448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orexin (hypocretin) innervation of the paraventricular nucleus of the thalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23162448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholecystokinin and substance P immunoreactive projections to the paraventricular thalamic nucleus in the rat

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https://pubmed.ncbi.nlm.nih.gov/23162448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FNBEH.2012.00075

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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