Adeno-associated virus mediated delivery of an engineered protein that combines the complement inhibitory properties of CD46, CD55 and CD59 (Q36380744)

13 August 2017

Adeno-associated virus mediated delivery of an engineered protein that combines the complement inhibitory properties of CD46, CD55 and CD59 (English)

1 reference

13 August 2017

Derek Leaderer

1

1 reference

13 August 2017

Siobhan M Cashman

series ordinal

2

1 reference

13 August 2017

Rajendra Kumar-Singh

series ordinal

3

1 reference

13 August 2017

27 April 2015

1 reference

13 August 2017

Journal of Gene Medicine

1 reference

13 August 2017

17

1 reference

13 August 2017

6-7

1 reference

13 August 2017

101-115

1 reference

describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4682684/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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30 September 2017

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Gene therapy clinical trials worldwide to 2012 - an update.

30 September 2017

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Decreased membrane complement regulators in the retinal pigmented epithelium contributes to age-related macular degeneration

30 September 2017

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30 September 2017

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Systemic errors in quantitative polymerase chain reaction titration of self-complementary adeno-associated viral vectors and improved alternative methods

30 September 2017

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PRELP protein inhibits the formation of the complement membrane attack complex

30 September 2017

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Development of Anti-VEGF Therapies for Intraocular Use: A Guide for Clinicians

30 September 2017

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C9-R95X polymorphism in patients with neovascular age-related macular degeneration

30 September 2017

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Expression of complement regulatory proteins CD55, CD59, CD35, and CD46 in rheumatoid arthritis.

30 September 2017

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Elevated membrane attack complex in human choroid with high risk complement factor H genotypes

30 September 2017

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Soluble CD59 expressed from an adenovirus in vivo is a potent inhibitor of complement deposition on murine liver vascular endothelium

30 September 2017

1 reference

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A non membrane-targeted human soluble CD59 attenuates choroidal neovascularization in a model of age related macular degeneration

30 September 2017

1 reference

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The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice

30 September 2017

1 reference

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Adenovirus-mediated delivery of CD46 attenuates the alternative complement pathway on RPE: implications for age-related macular degeneration

30 September 2017

1 reference

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Dynamic control of the complement system by modulated expression of regulatory proteins

30 September 2017

1 reference

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Decay accelerating factor (CD55)-mediated attenuation of complement: therapeutic implications for age-related macular degeneration

30 September 2017

1 reference

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The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited

30 September 2017

1 reference

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Complement regulators and inhibitory proteins

30 September 2017

1 reference

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The Paramyxoviruses Simian Virus 5 and Mumps Virus Recruit Host Cell CD46 To Evade Complement-Mediated Neutralization

30 September 2017

1 reference

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Ocular gene therapy: current progress and future prospects

30 September 2017

1 reference

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The spectrum of complement alternative pathway-mediated diseases

30 September 2017

1 reference

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Evaluation of adenovirus-delivered human CD59 as a potential therapy for AMD in a model of human membrane attack complex formation on murine RPE.

30 September 2017

1 reference

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Complement is an essential component of the immune response to adeno-associated virus vectors

30 September 2017

1 reference

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Role of complement and complement regulators in the removal of apoptotic cells.

30 September 2017

1 reference

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The complement system in liver diseases

30 September 2017

1 reference

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AN ESTIMATION OF THE HEPATIC BLOOD FLOW AND SPLANCHNIC OXYGEN CONSUMPTION IN HEART FAILURE.

30 September 2017

1 reference

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Membrane complement regulatory proteins

30 September 2017

1 reference

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Production of recombinant adeno-associated virus vectors

30 September 2017

1 reference

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Complement factor H polymorphism in age-related macular degeneration

30 September 2017

1 reference

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CD46: expanding beyond complement regulation

30 September 2017

1 reference

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Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

30 September 2017

1 reference

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Complement. First of two parts

30 September 2017

1 reference

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Therapeutic inhibition of the complement system.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682684

Complement in acute and chronic arthritides: assessment of C3c, C9, and protectin (CD59) in synovial membrane

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682684

Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors.

30 September 2017

1 reference

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Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease

30 September 2017

1 reference

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Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682684

Biochemical characterization of membrane cofactor protein of the complement system.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682684

A novel bifunctional chimeric complement inhibitor that regulates C3 convertase and formation of the membrane attack complex.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682684

Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682684

Mapping of epitopes, glycosylation sites, and complement regulatory domains in human decay accelerating factor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682684

Effect of adeno-associated virus serotype and genomic structure on liver transduction and biodistribution in mice of both genders

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682684

Complications in patients after intravitreal injection of bevacizumab.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682684

Immunohistochemical determination of complement activation in joint tissues of patients with rheumatoid arthritis and osteoarthritis using neoantigen-specific monoclonal antibodies

21 September 2018

1 reference

12 December 2020

Complement and systemic lupus erythematosus

1 reference

12 December 2020

Twelve-month safety of intravitreal injections of bevacizumab (Avastin®): results of the Pan-American Collaborative Retina Study Group (PACORES)

1 reference

12 December 2020

A recombinant soluble chimeric complement inhibitor composed of human CD46 and CD55 reduces acute cardiac tissue injury in models of pig-to-human heart transplantation

1 reference

12 December 2020

Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis

1 reference

12 December 2020

Humoral injury in porcine livers perfused with human whole blood

1 reference

12 December 2020

Identifiers

DOI

10.1002/JGM.2829

1 reference

release_wpuwufsxcreydat2bothkti2d4

13 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wpuwufsxcreydat2bothkti2d4

24 November 2022

mapped directly with Wikidata item

1 reference

13 August 2017

1 reference