The Trypanosoma cruzi trans-sialidase, through its COOH-terminal tandem repeat, upregulates interleukin 6 secretion in normal human intestinal microvascular endothelial cells and peripheral blood mononuclear cells (Q36375616)

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English	The Trypanosoma cruzi trans-sialidase, through its COOH-terminal tandem repeat, upregulates interleukin 6 secretion in normal human intestinal microvascular endothelial cells and peripheral blood mononuclear cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

The Trypanosoma cruzi trans-sialidase, through its COOH-terminal tandem repeat, upregulates interleukin 6 secretion in normal human intestinal microvascular endothelial cells and peripheral blood mononuclear cells (English)

1 reference

Europe PubMed Central

13 August 2017

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Trypanosoma cruzi

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1 reference

based on heuristic

inferred from title

author name string

E Saavedra

1

1 reference

Europe PubMed Central

13 August 2017

M Herrera

2

1 reference

Europe PubMed Central

13 August 2017

W Gao

3

1 reference

Europe PubMed Central

13 August 2017

H Uemura

4

1 reference

Europe PubMed Central

13 August 2017

M A Pereira

5

1 reference

Europe PubMed Central

13 August 2017

language of work or name

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publication date

1 December 1999

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Europe PubMed Central

13 August 2017

Journal of Experimental Medicine

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Europe PubMed Central

13 August 2017

190

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Europe PubMed Central

13 August 2017

12

1 reference

Europe PubMed Central

13 August 2017

1825-1836

1 reference

Europe PubMed Central

13 August 2017

Endogenous IL-1alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195715

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Cytokine profiles of cultured microvascular endothelial cells from the human intestine

1 reference

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Bacterial perturbation of cytokine networks

1 reference

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Physiological and pathological roles of interleukin-6 in the central nervous system

1 reference

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Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense

1 reference

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30 September 2017

Passive transfer of a monoclonal antibody specific for a sialic acid-dependent epitope on the surface of Trypanosoma cruzi trypomastigotes reduces infection in mice

1 reference

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HIV-1 Tat induces the expression of the interleukin-6 (IL6) gene by binding to the IL6 leader RNA and by interacting with CAAT enhancer-binding protein beta (NF-IL6) transcription factors

1 reference

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Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells

1 reference

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Invasive phenotype of Trypanosoma cruzi restricted to a population expressing trans-sialidase

1 reference

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1 reference

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1 reference

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Role of microvascular endothelial cells in inflammation

1 reference

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Mammalian cell sialic acid enhances invasion by Trypanosoma cruzi.

1 reference

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Interleukin-6 (IL-6) production in mice infected with Trypanosoma cruzi: effect of its paradoxical increase by anti-IL-6 monoclonal antibody treatment on infection and acute-phase and humoral immune responses

1 reference

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1 reference

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30 September 2017

Mice infected with Trypanosoma cruzi produce antibodies against the enzymatic domain of trans-sialidase that inhibit its activity.

1 reference

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Differentiation of endothelial cells: analysis of the constitutive and activated endothelial cell phenotypes

1 reference

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Structural and functional properties of Trypanosoma trans-sialidase

1 reference

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Trypanosoma cruzi trans-sialidase: enhancement of virulence in a murine model of Chagas' disease

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Monoclonal antibodies against Trypanosoma cruzi neuraminidase reveal enzyme polymorphism, recognize a subset of trypomastigotes, and enhance infection in vitro.

1 reference

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1 reference

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The Trypanosoma cruzi neuraminidase contains sequences similar to bacterial neuraminidases, YWTD repeats of the low density lipoprotein receptor, and type III modules of fibronectin

1 reference

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1 reference

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30 September 2017

Only some members of a gene family in Trypanosoma cruzi encode proteins that express both trans-sialidase and neuraminidase activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195715

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Trypanosoma cruzi trans-sialidase gene lacking C-terminal repeats and expressed in epimastigote forms

1 reference

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Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene

1 reference

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Persistent production of inflammatory and anti-inflammatory cytokines and associated MHC and adhesion molecule expression at the site of infection and disease in experimental Trypanosoma cruzi infections.

1 reference

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Trans-sialidase from Trypanosoma cruzi epimastigotes is expressed at the stationary phase and is different from the enzyme expressed in trypomastigotes.

1 reference

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1 reference

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Identification of the gene(s) coding for the trans-sialidase of Trypanosoma cruzi

1 reference

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1 reference

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A Developmentally Regulated Neuraminidase Activity in Trypanosoma cruzi

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Cell-mediated immunity in experimental Trypanosoma cruzi infection

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Antibody to Trypanosoma cruzi neuraminidase enhances infection in vitro and identifies a subpopulation of trypomastigotes

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10601357

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The biology of interleukin-6

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Infection with HIV is associated with elevated IL-6 levels and production

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Cytokine patterns of immunologically mediated tissue damage

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Coculture of human peripheral blood mononuclear cells with Trypanosoma cruzi leads to proliferation of lymphocytes and cytokine production

1 reference

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A novel T. cruzi heparin-binding protein promotes fibroblast adhesion and penetration of engineered bacteria and trypanosomes into mammalian cells

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Inducible production of interleukin-6 by human polymorphonuclear neutrophils: role of granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha

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Identifiers

10.1084/JEM.190.12.1825

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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