The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure. (Q36370082)

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English	The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure.	scientific article

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3 December 2019

The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure (English)

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3 December 2019

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Leishmania major

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Yasmine Belkaid

1

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3 December 2019

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K F Hoffmann

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3 December 2019

S Mendez

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S Kamhawi

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M C Udey

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T A Wynn

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D L Sacks

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1 November 2001

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3 December 2019

Journal of Experimental Medicine

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3 December 2019

194

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3 December 2019

1497-1506

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3 December 2019

10

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3 December 2019

Anti-interleukin 10 receptor monoclonal antibody is an adjuvant for T helper cell type 1 responses to soluble antigen only in the presence of lipopolysaccharide

1 reference

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30 September 2017

The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge

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30 September 2017

Fibroblasts as host cells in latent leishmaniosis

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30 September 2017

Chronic colitis in IL-10-/- mice: insufficient counter regulation of a Th1 response.

1 reference

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30 September 2017

Regulatory T cells and inflammatory bowel disease

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30 September 2017

A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells

1 reference

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30 September 2017

Development of a natural model of cutaneous leishmaniasis: powerful effects of vector saliva and saliva preexposure on the long-term outcome of Leishmania major infection in the mouse ear dermis

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30 September 2017

Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity

1 reference

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30 September 2017

Immunologic determinants of disease evolution in localized cutaneous leishmaniasis due to Leishmania major

1 reference

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30 September 2017

Identification of a T cell subset capable of both IFN-gamma and IL-10 secretion in patients with chronic Borrelia burgdorferi infection.

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30 September 2017

IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways

1 reference

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30 September 2017

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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30 September 2017

Altered immune responses in interleukin 10 transgenic mice

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30 September 2017

Leishmania and human immunodeficiency virus coinfection: the first 10 years

1 reference

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30 September 2017

Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

30 September 2017

Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

30 September 2017

Dendritic cells seclude Leishmania parasites that persist in cured mice--a role in the maintenance of T-cell memory?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

30 September 2017

Increased expression of proinflammatory cytokines in chronic lesions of human cutaneous leishmaniasis

1 reference

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30 September 2017

Persistence of virulent Leishmania major in murine cutaneous leishmaniasis: a possible hazard for the host

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

30 September 2017

Analysis of the cellular parameters of the immune responses contributing to resistance and susceptibility of mice to infection with the intracellular parasite, Leishmania major

1 reference

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30 September 2017

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism

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30 September 2017

IL-10 inhibits cytokine production by activated macrophages

1 reference

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30 September 2017

The role of IL-10 in crossregulation of TH1 and TH2 responses

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30 September 2017

Post kala-azar dermal leishmaniasis in the Sudan: clinical features, pathology and treatment

1 reference

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30 September 2017

Persistent infections by Leishmania (Viannia) braziliensis

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28 June 2018

A limiting dilution assay for quantifying Leishmania major in tissues of infected mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

28 June 2018

IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

28 June 2018

Role of T cell subsets during the recall of immunologic memory to Leishmania major

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

28 June 2018

Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells

1 reference

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21 September 2018

A natural model of Leishmania major infection reveals a prolonged "silent" phase of parasite amplification in the skin before the onset of lesion formation and immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

21 September 2018

IL-12 is required to maintain a Th1 response during Leishmania major infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

21 September 2018

Interleukin 10-mediated immunosuppression by a variant CD4 T cell epitope of Plasmodium falciparum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

21 September 2018

Studies with double cytokine-deficient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni

1 reference

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21 September 2018

Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

21 September 2018

Clinical picture of cutaneous leishmaniasis in Isfahan, Iran.

1 reference

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21 September 2018

Mucocutaneous leishmaniasis in Colombia: Leishmania braziliensis subspecies diversity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193677

21 September 2018

Evidence for functional relevance of CTLA-4 in ultraviolet-radiation-induced tolerance

1 reference

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21 October 2018

High levels of plasma IL-10 and expression of IL-10 by keratinocytes during visceral leishmaniasis predict subsequent development of post-kala-azar dermal leishmaniasis

1 reference

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21 October 2018

Interleukin-10 inhibits antimicrobial activity against Leishmania major in murine macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psoriatic skin-derived dendritic cell function is inhibited by exogenous IL-10. Differential modulation of B7-1 (CD80) and B7-2 (CD86) expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine epidermal Langerhans cells do not express inducible nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E-cadherin-mediated adhesion involving Langerhans cell-like dendritic cells expanded from murine fetal skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of Leishmania DNA by polymerase chain reaction in scars of treated human patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental Leishmania major infection in mice: role of IL-10

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-γ- and Tumour Necrosis Factor-α-Producing Cells in Humans who are Immune to Cutaneous Leishmaniasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ T Cell Clones Producing both Interferon-γ and Interleukin-10 Predominate in Bronchoalveolar Lavages of Active Pulmonary Tuberculosis Patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct innate and acquired immune responses to Leishmania in putative susceptible and resistant human populations endemically exposed to L. (Viannia) panamensis infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12p70 production by Leishmania major-harboring human dendritic cells is a CD40/CD40 ligand-dependent process

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection Against Cutaneous Leishmaniasis Resulting from Bites of Uninfected Sand Flies

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of IL-10 in promoting disease progression in leishmaniasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunity to experimental infection with Leishmania major: generation of protective L3T4+ T cell clones recognizing antigen(s) associated with live parasites

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-10 inhibits human T cell proliferation and IL-2 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine control of Leishmania infection in the BALB/c mouse: enhancement and inhibition of parasite growth by local administration of IL-2 or IL-4 is species and time dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/11714756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.194.10.1497

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11714756%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11714756%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11714756%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

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