Widespread tissue distribution and diverse functions of corticotropin-releasing factor and related peptides (Q36368341)

13 August 2017

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title

Widespread tissue distribution and diverse functions of corticotropin-releasing factor and related peptides (English)

1 reference

13 August 2017

Graham C Boorse

1

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PubMed ID

16413023

13 August 2017

Robert J Denver

series ordinal

2

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13 August 2017

18 January 2006

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General and Comparative Endocrinology

13 August 2017

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13 August 2017

146

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13 August 2017

1

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13 August 2017

9-18

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Corticotropin-releasing factor receptors: distribution and regulation in brain, pituitary, and peripheral tissues

13 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Characterization of three corticotropin-releasing factor receptors in catfish: a novel third receptor is predominantly expressed in pituitary and urophysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Expression of genes encoding corticotropin-releasing factor (CRF), type 1 CRF receptor, and CRF-binding protein and localization of the gene products in the human ovary

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

mRNA expression profiles for corticotrophin-releasing factor (CRF), urocortin, CRF receptors and CRF-binding protein in peripheral rat tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

The cardiovascular physiologic actions of urocortin II: acute effects in murine heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin releasing factor (CRF) binding protein: a novel regulator of CRF and related peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Characterization of a sheep brain corticotropin releasing factor binding protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Acceleration of Ambystoma tigrinum metamorphosis by corticotropin-releasing hormone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Endocrine mechanisms underlying plasticity in metamorphic timing in spadefoot toads

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Expression and hypophysiotropic actions of corticotropin-releasing factor in Xenopus laevis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortins of the South African clawed frog, Xenopus laevis: conservation of structure and function in tetrapod evolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing factor is cytoprotective in Xenopus tadpole tail: coordination of ligand, receptor, and binding protein in tail muscle cell survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

CRH-like peptides protect cardiac myocytes from lethal ischaemic injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin protects against ischemic and reperfusion injury via a MAPK-dependent pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

The thyroid hormone-induced tail resorption program during Xenopus laevis metamorphosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Evidence that urocortin I acts as a neurohormone to stimulate alpha MSH release in the toad Xenopus laevis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Isolation and Characterisation of the Corticotropin Releasing Factor Receptor 1 (CRFR1) Gene in a Teleost Fish,Fugu rubripes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Stress, neuropeptides, and feeding behavior: a comparative perspective

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotrophin-releasing factor receptors: from molecular biology to drug design

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

CRF receptor type 1 and 2 expression and anatomical distribution in the rat colon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Differential profile of CRF receptor distribution in the rat stomach and duodenum assessed by newly developed CRF receptor antibodies.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Expression cloning of a human corticotropin-releasing-factor receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin II gene is highly expressed in mouse skin and skeletal muscle tissues: localization, basal expression in corticotropin-releasing factor receptor (CRFR) 1- and CRFR2-null mice, and regulation by glucocorticoids.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

A soluble mouse brain splice variant of type 2alpha corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin-induced relaxation in the human internal mammary artery.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Molecular and biochemical characterization of the mouse brain corticotropin-releasing hormone-binding protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing hormone-related peptides and receptors: emergent regulators of cardiovascular adaptations to stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Ontogeny of corticotropin-releasing factor effects on locomotion and foraging in the Western spadefoot toad (Spea hammondii).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Roles of stress hormones in food intake regulation in anuran amphibians throughout the life cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Roles of corticotropin-releasing factor, neuropeptide Y and corticosterone in the regulation of food intake in Xenopus laevis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Identification of two corticotropin-releasing factor receptors from Xenopus laevis with high ligand selectivity: unusual pharmacology of the type 1 receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

The CRF peptide family and their receptors: yet more partners discovered

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing hormone (CRH)-induced thyrotropin release is directly mediated through CRH receptor type 2 on thyrotropes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Several hypothalamic peptides stimulate in vitro thyrotropin secretion by pituitaries of anuran amphibians

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Acceleration of anuran amphibian metamorphosis by corticotropin-releasing hormone-like peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Environmental stress as a developmental cue: corticotropin-releasing hormone is a proximate mediator of adaptive phenotypic plasticity in amphibian metamorphosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Evolution of the corticotropin-releasing hormone signaling system and its role in stress-induced phenotypic plasticity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Cloning and characterization of human urocortin [published erratum appears in Endocrinoogy 1996 Sep;137(9):3896]

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Distribution of Corticotropin Releasing Hormone in the Fetus, Newborn, Juvenile, and Adult Baboon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Direct effects of corticotropin-releasing hormone and thyrotropin-releasing hormone on fetal lung explants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Neuroprotection by corticotropin releasing factor during hypoxia in rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urotensin I, a CRF-like neuropeptide, stimulates acth release from the teleost pituitary

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

ACTH-releasing activity of urotensin I and ovine CRF: interactions with arginine vasotocin, isotocin and arginine vasopressin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing factor stimulates metamorphosis and increases thyroid hormone concentration in prometamorphic Rana perezi larvae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Sauvagine-like and corticotropin-releasing factor-like immunoreactivity in the brain of the bullfrog (Rana catesbeiana)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Dilatory and inotropic effects of corticotropin-releasing factor (CRF) on the isolated heart. Effects on atrial natriuretic peptide (ANP) release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Stimulation of rat pancreatic exocrine secretion by urocortin and corticotropin releasing factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Endotoxin regulates corticotropin-releasing hormone receptor 2 in heart and skeletal muscle.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing hormone receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

The remarkable conservation of corticotropin-releasing hormone (CRH)-binding protein in the honeybee (Apis mellifera) dates the CRH system to a common ancestor of insects and vertebrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin Expression in Human Pituitary Gland and Pituitary Adenoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin expression in the human central nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin has cell-proliferative effects on cardiac non-myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Molecular cloning of bullfrog corticotropin-releasing factor (CRF): effect of homologous CRF on the release of TSH from pituitary cells in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

An antisense oligodeoxynucleotide complementary to corticotropin-releasing hormone mRNA inhibits rat splenocyte proliferation in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

A role for corticotropin releasing factor and urocortin in behavioral responses to stressors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Complete amino acid sequence of urotensin I, a hypotensive and corticotropin-releasing neuropeptide from Catostomus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin III is expressed in pancreatic beta-cells and stimulates insulin and glucagon secretion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Evolution and physiology of the corticotropin-releasing factor (CRF) family of neuropeptides in vertebrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing factor enhances locomotion and medullary neuronal firing in an amphibian.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing factor accelerates metamorphosis in Bufo arenarum: effect on pituitary ACTH and TSH cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin releasing hormone stimulates proliferation of keratinocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Amino acid composition and sequence analysis of sauvagine, a new active peptide from the skin of Phyllomedusa sauvagei

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Expression of the mouse corticotropin-releasing hormone gene in vivo and targeted inactivation in embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin and corticotropin-releasing factor receptor expression in the human colonic mucosa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Immunohistochemical studies on the development of the hypothalamo-hypophysial system in Xenopus laevis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Development of radioimmunoassay for bullfrog thyroid-stimulating hormone (TSH): effects of hypothalamic releasing hormones on the release of TSH from the pituitary in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Cloning and sequence analysis of cDNA for corticotropin-releasing factor precursor from the teleost fish Catostomus commersoni

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Distribution and concentration of urocortin, and effect of adrenalectomy on its content in rat hypothalamus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Localization and physiological roles of urocortin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Immunocytochemical localization and spatial relation to the adenohypophysis of a somatostatin-like and a corticotropin-releasing factor-like peptide in the brain of four amphibian species

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing factor receptor type 1 from Tupaia belangeri--cloning, functional expression and tissue distribution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Isolation and pharmacological characterization of two functional splice variants of corticotropin-releasing factor type 2 receptor from Tupaia belangeri

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin, but not urocortin II, protects cultured hippocampal neurons from oxidative and excitotoxic cell death via corticotropin-releasing hormone receptor type I

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing factor (CRF)-like immunoreactivity in the vertebrate endocrine pancreas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing factor (CRF)-like immunoreactivity in the gastro-entero-pancreatic endocrine system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Cloning and functional pharmacology of two corticotropin-releasing factor receptors from a teleost fish

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Cloning and characterization of the cDNAs for human and rat corticotropin releasing factor-binding proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

The central distribution of a corticotropin-releasing factor (CRF)-binding protein predicts multiple sites and modes of interaction with CRF

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Distribution of corticotropin-releasing factor receptor mRNA expression in the rat brain and pituitary

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing factor (CRF) rapidly suppresses apoptosis by acting upstream of the activation of caspases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Expression of CRF1 and CRF2 receptors in human cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin 3/stresscopin in human colon: possible modulators of gastrointestinal function during stressful conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Mouse models of altered CRH-binding protein expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing hormone-binding protein: biochemistry and function from fishes to mammals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Corticotropin-releasing hormone system in human adipose tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Ultraviolet B stimulates production of corticotropin releasing factor (CRF) by human melanocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

The skin produces urocortin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Cutaneous expression of corticotropin-releasing hormone (CRH), urocortin, and CRH receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Differential expression of a cutaneous corticotropin-releasing hormone system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

The role of CRH in behavioral responses to stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Distribution and Characterization of Immunoreactive Corticotropin-Releasing Factor in Human Tissues*

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Expression and characterisation of human and rat CRF2alpha receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Expression of urocortin III/stresscopin in human heart and kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortins as cardiovascular peptides.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Comparative effects of corticotropin-releasing factor, arginine vasopressin, and related neuropeptides on the secretion of ACTH and alpha-MSH by frog anterior pituitary cells and neurointermediate lobes in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

CRF, urotensin I, and sauvagine stimulate the release of POMC-derived peptides from goldfish neurointermediate lobe cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Biochemical characterization and expression analysis of the Xenopus laevis corticotropin-releasing hormone binding protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Localization of CRF immunoreactivity in the central nervous system of three vertebrate and one insect species.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Distribution and acute stressor-induced activation of corticotrophin-releasing hormone neurones in the central nervous system of Xenopus laevis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Induction of apoptosis and CPP32 expression by thyroid hormone in a myoblastic cell line derived from tadpole tail

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Molecular cloning of a type A chicken corticotropin-releasing factor receptor with high affinity for urotensin I.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

Aspects of amphibian metamorphosis: hormonal control

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2005.11.014

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YGCEN.2005.11.014

1 reference

13 August 2017

1 reference

PubMed ID

16413023