Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells. (Q36367466)

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English	Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.	scientific article

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20 October 2019

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells (English)

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20 October 2019

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20 October 2019

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20 October 2019

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H Kanzler

1

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20 October 2019

M L Hansmann

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1 October 1996

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20 October 2019

Journal of Experimental Medicine

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20 October 2019

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20 October 2019

1495-1505

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20 October 2019

4

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20 October 2019

Expression of CD95 antigen and Bcl-2 protein in non-Hodgkin's lymphomas and Hodgkin's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

Genetic instability in patients with Hodgkin's disease undergoing chemotherapy

1 reference

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30 September 2017

Epstein-Barr Virus DNA recombination and loss in sporadic Burkitt's lymphoma

1 reference

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30 September 2017

Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

The variable genes of the human immunoglobulin kappa locus

1 reference

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30 September 2017

Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections

1 reference

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30 September 2017

A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group

1 reference

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30 September 2017

The cellular biology of the Reed-Sternberg cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

Analysis of somatic mutation in five B cell subsets of human tonsil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

The Reed-Sternberg cells of Hodgkin disease are clonal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

Somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

New characterization of infectious mononucleosis and a phenotypic comparison with Hodgkin's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

Report of the Committee on Hodgkin's Disease Staging Classification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

Clonal evolution of a follicular lymphoma: evidence for antigen selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

Molecular characterization of the human immunoglobulin V lambda I germline gene repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

Recent results on the biology of Hodgkin and Reed-Sternberg cells. I. Biopsy material

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

30 September 2017

Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig kappa enh

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

28 June 2018

Structure and physical map of 64 variable segments in the 3'0.8-megabase region of the human immunoglobulin heavy-chain locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

28 June 2018

Hodgkin's disease with monoclonal and polyclonal populations of Reed-Sternberg cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

28 June 2018

A novel form of Epstein-Barr virus latency in normal B cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

28 June 2018

Rearranged antigen receptor genes in Hodgkin's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

28 June 2018

Demonstration of monoclonal EBV genomes in Hodgkin's disease and Ki-1-positive anaplastic large cell lymphoma by combined Southern blot and in situ hybridization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

28 June 2018

Germinal center cells express bcl-2 protein after activation by signals which prevent their entry into apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

28 June 2018

Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

28 June 2018

Molecular single-cell analysis of Hodgkin and Reed-Sternberg cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

21 September 2018

Human IgM+IgD+ B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

21 September 2018

Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

21 September 2018

A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

21 September 2018

Immunoglobulin V Genes in Reed–Sternberg Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

5 December 2018

High gradient magnetic cell separation with MACS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192840

5 December 2018

Numerical chromosome aberrations are present within the CD30+ Hodgkin and Reed-Sternberg cells in 100% of analyzed cases of Hodgkin's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8879220

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of Reed-Sternberg cells from lymph nodes of Hodgkin's disease patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/8879220

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hodgkin cells accumulate mRNA for bcl-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/8879220

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoglobulin V genes in Reed-Sternberg cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8879220

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoglobulin V genes in Reed-Sternberg cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8879220

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of Epstein-Barr viral genomes in Reed-Sternberg cells of Hodgkin's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8879220

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo somatic mutation in the lymphocytes of Hodgkin's disease patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/8879220

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-cell analysis of Hodgkin and Reed-Sternberg cells: molecular heterogeneity of gene expression and p53 mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/8879220

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nodular lymphocyte predominance Hodgkin's disease. A distinct clinicopathological entity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8879220

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of immunoglobulin heavy-chain gene rearrangement at the single-cell level in malignant lymphomas: no rearrangement is found in Hodgkin and Reed-Sternberg cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8879220

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.184.4.1495

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8879220%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8879220%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8879220%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

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