Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice (Q36362973)

13 August 2017

Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice (English)

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13 August 2017

3

Glimcher LH

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13 August 2017

2

Grusby MJ

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13 August 2017

Jevnikar AM

1

1 reference

PMCID

2191453

13 August 2017

language of work or name

English

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publication date

1 April 1994

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Journal of Experimental Medicine

13 August 2017

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13 August 2017

179

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13 August 2017

1137-1143

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13 August 2017

4

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The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Treatment of (NZB x NZW)F1 disease with anti-I-A monoclonal antibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Etiopathogenesis of Murine SLE1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Reactive lymphocytes in lacrimal gland and vasculitic renal lesions of autoimmune MRL/lpr mice express L3T4.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Clonal diversity and T-cell receptor beta-chain variable gene expression in enlarged lymph nodes of MRL-lpr/lpr lupus mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Enhanced MHC class II expression in renal proximal tubules precedes loss of renal function in MRL/lpr mice with lupus nephritis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Transgenic rearranged T cell receptor gene inhibits lymphadenopathy and accumulation of CD4-CD8-B220+ T cells in lpr/lpr mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Anti-CD4 monoclonal antibody therapy suppresses autoimmune disease in MRL/Mp-lpr/lpr mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Dexamethasone prevents autoimmune nephritis and reduces renal expression of Ia but not costimulatory signals

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Origin of CD4-CD8-B220+ T cells in MRL-lpr/lpr mice. Clues from a T cell receptor beta transgenic mouse.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Evidence for early onset, polyclonal activation of T cell subsets in mice homozygous for lpr

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

CD2-CD4-CD8- lymph node T lymphocytes in MRL lpr/lpr mice are derived from a CD2+CD4+CD8+ thymic precursor.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191453

Autoreactive kidney-infiltrating T-cell clones in murine lupus nephritis

22 September 2018

1 reference

12 December 2020

Induction of various autoantibodies by mutant gene lpr in several strains of mice

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12 December 2020

CS-A therapy in MRL-lpr/lpr mice: amelioration of immunopathology despite autoantibody production

1 reference

12 December 2020

Prevention of lymphadenopathy in MRL-lpr/lpr mice by blocking peripheral lymph node homing with Mel-14 in vivo

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12 December 2020

B lymphocyte development and activation independent of MHC class II expression

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12 December 2020

Selection of the T cell receptor repertoire in Lpr mice

1 reference

12 December 2020

Autoreactive T cells in MRL/Mpr-lpr/lpr mice. Characterization of the lymphokines produced and analysis of antigen-presenting cells required

1 reference

12 December 2020

Abnormal T cells from lpr mice down-regulate transcription of interferon-gamma and tumor necrosis factor-alpha in vitro

1 reference

12 December 2020

Abnormal thymocyte development and production of autoreactive T cells in T cell receptor transgenic autoimmune mice

1 reference

12 December 2020

Transgenic T cell receptor interactions in the lymphoproliferative and autoimmune syndromes of lpr and gld mutant mice

1 reference

12 December 2020

Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.179.4.1137

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

PMCID

2191453