Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance (Q36350528)

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Effect of Genetic Polymorphisms in Cytochrome P450 (CYP) 2C9 and CYP2C8 on the Pharmacokinetics of Oral Antidiabetic Drugs

Language	Label	Description	Also known as
English	Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance	scientific article	Effect of Genetic Polymorphisms in Cytochrome P450 (CYP) 2C9 and CYP2C8 on the Pharmacokinetics of Oral Antidiabetic Drugs

Statements

scholarly article

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance (English)

1 reference

Europe PubMed Central

13 August 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Julia Kirchheiner

1

1 reference

Europe PubMed Central

13 August 2017

Ivar Roots

2

1 reference

Europe PubMed Central

13 August 2017

Mark Goldammer

3

1 reference

Europe PubMed Central

13 August 2017

Bernd Rosenkranz

4

1 reference

Europe PubMed Central

13 August 2017

Jürgen Brockmöller

5

1 reference

Europe PubMed Central

13 August 2017

publication date

1 January 2005

1 reference

Europe PubMed Central

13 August 2017

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

13 August 2017

44

1 reference

Europe PubMed Central

13 August 2017

12

1 reference

Europe PubMed Central

13 August 2017

1209-1225

1 reference

Europe PubMed Central

13 August 2017

https://scigraph.springernature.com/pub.10.2165/00003088-200544120-00002

0 references

Pharmacologic therapy for type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200544120-00002

21 January 2018

A screening test for slow metabolisers of tolbutamide

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200544120-00002

21 January 2018

Lack of relationship between glibenclamide metabolism and debrisoquine or mephenytoin hydroxylation phenotypes

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200544120-00002

21 January 2018

Metabolism, Blood Levels and Rate of Excretion of Acetohexamide in Human Subjects

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200544120-00002

21 January 2018

Thiazolidinediones, Peripheral Edema, and Type 2 Diabetes: Incidence, Pathophysiology, and Clinical Implications

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200544120-00002

21 January 2018

Chlorpropamide and glibenclamide serum concentrations in hospitalized patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of rosiglitazone in patients with varying degrees of renal insufficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Slow elimination of glyburide in NIDDM subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between CYP2C9 slow metabolizer genotypes and severe hypoglycaemia on medication with sulphonylurea hypoglycaemic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic basis for the safety of glimepiride in risk groups of NIDDM patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inheritance and drug response

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[The relatively frequent incidence of severe sulfonylurea-induced hypoglycemia in the last 25 years in Switzerland. Results of 2 surveys in Switzerland in 1969 and 1984]

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between the pharmacokinetics and pharmacodynamic effects of oral hypoglycaemic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel D-phenylalanine-derivative hypoglycemic agent A-4166 increases cytosolic free Ca2+ in rat pancreatic beta-cells by stimulating Ca2+ influx

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of nateglinide: a rapidly-absorbed, short-acting insulinotropic agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gliclazide. An update of its pharmacological properties and therapeutic efficacy in non-insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioavailability, pharmacokinetics and effects of glipizide in type 2 diabetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired effect of sulfonylurea following increased dosage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Sulfonylurea-induced hypoglycemia. An iatrogenic and potentially fatal condition]

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 2C9 phenotyping using low-dose tolbutamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage between the CYP2C8 and CYP2C9 genetic polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulfonylureas. Why, which, and how?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and metabolism of nateglinide in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pumping liquids using asymmetric electrode arrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pioglitazone: effect on CYP3A4 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glibenclamide-associated hypoglycaemia: a report on 57 cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytochrome P4503A4 inhibitor clarithromycin increases the plasma concentrations and effects of repaglinide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacology of sulphonylurea hypoglycaemic agents: part 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of CYP2C19 and CYP2C9 genetic polymorphisms on the disposition of and blood glucose lowering response to tolbutamide in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure determination of metabolites isolated from urine and bile after administration of AY4166, a novel D-phenylalanine-derivative hypoglycemic agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gliclazide hydroxylation by rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of cytochrome P4502C9 metabolic activity with tolbutamide in CYP2C91 heterozygotes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral antihyperglycemic therapy for type 2 diabetes: scientific review

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes in America: epidemiology and scope of the problem

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mealtime glucose regulation with nateglinide in healthy volunteers: comparison with repaglinide and placebo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of relationship between tolbutamide metabolism and debrisoquine oxidation phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of glimepiride and cytochrome P450 2C9 genetic polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects and serum levels of glibenclamide and its active metabolites in patients with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolbutamide hydroxylation in humans: lack of bimodality in 106 healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic association between sensitivity to warfarin and expression of CYP2C9*3

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human CYP2C locus: a prototype for intergenic and exon repetition splicing events

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

American Diabetes Association Clinical Practice Recommendations 2001

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of chlorpropamide in epileptic patients: effects of enzyme induction and urine pH on chlorpropamide elimination

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal metabolism of debrisoquine and theophylline in a slow tolbutamide metaboliser

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of CYP2C9 and CYP2C19 polymorphisms on tolbutamide kinetics and the insulin and glucose response in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the bioavailability of glibenclamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolic fate of tolbutamide in man and in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human organic anion transporters and human organic cation transporters mediate renal antiviral transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics and pharmacodynamics of repaglinide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of extended-release glipizide GITS compared with immediate-release glipizide in patients with type II diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes guidelines: a summary and comparison of the recommendations of the American Diabetes Association, Veterans Health Administration, and American Association of Clinical Endocrinologists

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP2C8 and CYP3A4 are the principal enzymes involved in the human in vitro biotransformation of the insulin secretagogue repaglinide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of human cytochrome P450 2C9 with bound warfarin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and Kinetics of the Hypoglycemic Agent Glipizide in Man—Comparison with Glibenclamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoglycemic activity of glyburide (glibenclamide) metabolites in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of cytochrome P450 probe substrates commonly used by the pharmaceutical industry to study in vitro drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetics of tolbutamide metabolism in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics of pioglitazone in patients with impaired renal function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intensive diabetes management: implications of the DCCT and UKPDS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new hypoglycemic agent, A-4166, inhibits ATP-sensitive potassium channels in rat pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of troglitazone-induced liver injury with mutation of the cytochrome P450 2C19 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nateglinide improves glycaemic control when added to metformin monotherapy: results of a randomized trial with type 2 diabetes patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glyburide and glimepiride pharmacokinetics in subjects with different CYP2C9 genotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabolizers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Hypoglycemia during treatment with sulfonylurea preparations]

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetic diagnostics of cytochrome P450 polymorphisms in clinical drug development and in drug treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P4502C9: an enzyme of major importance in human drug metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between troglitazone cytotoxicity and drug metabolic enzyme activities in cryopreserved human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP2C9 allelic variants: ethnic distribution and functional significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amiodarone N-deethylation by CYP2C8 and its variants, CYP2C8*3 and CYP2C8 P404A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of rifampin on the pharmacokinetics and pharmacodynamics of glyburide and glipizide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of CYP2C9 amino acid polymorphisms on glyburide kinetics and on the insulin and glucose response in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of CYP2C9 and CYP2D6 polymorphisms on the pharmacokinetics of nateglinide in genotyped healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and clinical efficacy of pioglitazone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6α-hydroxylase activity in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatotoxicity with thiazolidinediones: is it a class effect?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic metabolism of tolbutamide: characterization of the form of cytochrome P-450 involved in methyl hydroxylation and relationship to in vivo disposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalytic activity of three variants (Ile, Leu, and Thr) at amino acid residue 359 in human CYP2C9 gene and simultaneous detection using single-strand conformation polymorphism analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-dose pharmacokinetics of repaglinide in subjects with chronic liver disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of the human cytochrome P450 CYP2C9 locus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk of Hypoglycaemia with Oral Antidiabetic Agents in Patients with Type 2 Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenomics--drug disposition, drug targets, and side effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of tolbutamide as a substrate probe for human hepatic cytochrome P450 2C9

1 reference

https://pubmed.ncbi.nlm.nih.gov/16372821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00003088-200544120-00002

1 reference

Europe PubMed Central

13 August 2017

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0 references

release_emn3iakryvc4lduw4knc6kgnnu

1 reference

https://api.fatcat.wiki/v0/release/emn3iakryvc4lduw4knc6kgnnu

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

13 August 2017

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