HIV vaccine design: insights from live attenuated SIV vaccines (Q36343536)

13 August 2017

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title

HIV vaccine design: insights from live attenuated SIV vaccines (English)

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13 August 2017

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3

David I Watkins

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13 August 2017

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Dennis R Burton

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Adrian B McDermott

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Kim J Hasenkrug

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Ronald C Desrosiers

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Jeffrey D Lifson

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Wayne C Koff

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Rosanne Boyle

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13 August 2017

Philip R Johnson

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13 August 2017

Alan Schultz

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8

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13 August 2017

Timothy J Zamb

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9

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13 August 2017

language of work or name

English

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publication date

1 January 2006

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13 August 2017

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7

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13 August 2017

19-23

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Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression f

13 August 2017

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Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag

21 January 2018

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Comparative efficacy of recombinant modified vaccinia virus Ankara expressing simian immunodeficiency virus (SIV) Gag-Pol and/or Env in macaques challenged with pathogenic SIV

21 January 2018

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Simian immunodeficiency virus (SIV) gag DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses and control viral replication after pathogenic SIV infection

21 January 2018

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Protective immunity induced by live attenuated simian immunodeficiency virus

21 January 2018

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Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene

21 January 2018

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Removal of N-linked glycosylation sites in the V1 region of simian immunodeficiency virus gp120 results in redirection of B-cell responses to V3.

21 January 2018

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Transient antiretroviral treatment during acute simian immunodeficiency virus infection facilitates long-term control of the virus

21 January 2018

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Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment

21 January 2018

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Resting naive CD4+ T cells are massively infected and eliminated by X4-tropic simian-human immunodeficiency viruses in macaques

21 January 2018

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Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

21 January 2018

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Immunization of macaques with single-cycle simian immunodeficiency virus (SIV) stimulates diverse virus-specific immune responses and reduces viral loads after challenge with SIVmac239

21 January 2018

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Mechanisms of protection induced by attenuated simian immunodeficiency virus. I. Protection cannot be transferred with immune serum.

21 January 2018

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Medicine. The need for a global HIV vaccine enterprise

21 January 2018

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HIV vaccine design and the neutralizing antibody problem

21 January 2018

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Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus

21 January 2018

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Protection from pathogenic SIVmac challenge following short-term infection with a nef-deficient attenuated virus

21 January 2018

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Quintuple deglycosylation mutant of simian immunodeficiency virus SIVmac239 in rhesus macaques: robust primary replication, tightly contained chronic infection, and elicitation of potent immunity against the parental wild-type strain

21 January 2018

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Novel adeno-associated virus vector vaccine restricts replication of simian immunodeficiency virus in macaques

21 January 2018

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Multispecific vaccine-induced mucosal cytotoxic T lymphocytes reduce acute-phase viral replication but fail in long-term control of simian immunodeficiency virus SIVmac239.

21 January 2018

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Vaccine protection against simian immunodeficiency virus by recombinant strains of herpes simplex virus

21 January 2018

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Protection against mucosal simian immunodeficiency virus SIV(mac251) challenge by using replicating adenovirus-SIV multigene vaccine priming and subunit boosting

21 January 2018

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Improved protection of rhesus macaques against intrarectal simian immunodeficiency virus SIV(mac251) challenge by a replication-competent Ad5hr-SIVenv/rev and Ad5hr-SIVgag recombinant priming/gp120 boosting regimen

21 January 2018

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ALVAC-SIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiency

21 January 2018

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Immunization with a modified vaccinia virus expressing simian immunodeficiency virus (SIV) Gag-Pol primes for an anamnestic Gag-specific cytotoxic T-lymphocyte response and is associated with reduction of viremia after SIV challenge

21 January 2018

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Immunization of newborn rhesus macaques with simian immunodeficiency virus (SIV) vaccines prolongs survival after oral challenge with virulent SIVmac251.

21 January 2018

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Induction of mucosal protection against primary, heterologous simian immunodeficiency virus by a DNA vaccine

21 January 2018

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Tat-vaccinated macaques do not control simian immunodeficiency virus SIVmac239 replication

21 January 2018

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Vaccine protection from CD4+ T-cell loss caused by simian immunodeficiency virus (SIV) mac251 is afforded by sequential immunization with three unrelated vaccine vectors encoding multiple SIV antigens.

21 January 2018

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Mucosal priming of simian immunodeficiency virus-specific cytotoxic T-lymphocyte responses in rhesus macaques by the Salmonella type III secretion antigen delivery system

21 January 2018

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Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles

21 January 2018

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Effective induction of simian immunodeficiency virus-specific systemic and mucosal immune responses in primates by vaccination with proviral DNA producing intact but noninfectious virions

21 January 2018

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Targeted lymph-node immunization with whole inactivated simian immunodeficiency virus (SIV) or envelope and core subunit antigen vaccines does not reliably protect rhesus macaques from vaginal challenge with SIVmac251.

21 January 2018

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Induction of anti-simian immunodeficiency virus cellular and humoral immune responses in rhesus macaques by peptide immunogens: correlation of CTL activity and reduction of cell-associated but not plasma virus load following challenge

21 January 2018

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Prospects for an AIDS vaccine

21 January 2018

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7 January 2021

Characterization of SIV-specific CD4+ T-helper proliferative responses in macaques immunized with live-attenuated SIV

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7 January 2021

Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.

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7 January 2021

An adenovirus-simian immunodeficiency virus env vaccine elicits humoral, cellular, and mucosal immune responses in rhesus macaques and decreases viral burden following vaginal challenge

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7 January 2021

A conformational C4 peptide polymer vaccine coupled with live recombinant vector priming is immunogenic but does not protect against rectal SIV challenge

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7 January 2021

Recombinant vaccine-induced protection against the highly pathogenic simian immunodeficiency virus SIV(mac251): dependence on route of challenge exposure.

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7 January 2021

DNA prime Listeria boost induces a cellular immune response to SIV antigens in the rhesus macaque model that is capable of limited suppression of SIV239 viral replication

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7 January 2021

Identifiers

DOI

10.1038/NI1296

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13 August 2017

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