Molecular subtypes of bladder cancer: Jekyll and Hyde or chalk and cheese? (Q36341182)

13 August 2017

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title

Molecular subtypes of bladder cancer: Jekyll and Hyde or chalk and cheese? (English)

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13 August 2017

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1

Margaret A Knowles

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PubMed ID

16352616

13 August 2017

language of work or name

English

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publication date

13 December 2005

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13 August 2017

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13 August 2017

27

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13 August 2017

361-373

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13 August 2017

3

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13 August 2017

Cancer statistics, 2003.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Urothelial tumorigenesis: a tale of divergent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

The natural history of bladder cancer. Implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

The genetics of transitional cell carcinoma: progress and potential clinical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Loss of heterozygosity at 4p16.3 and mutation of FGFR3 in transitional cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Amplification and over-expression of c-erbB-2 in transitional cell carcinoma of the urinary bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Oncogene amplification in urothelial cancers with p53 gene mutation or MDM2 amplification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Amplification and overexpression of E2F3 in human bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

High-resolution analysis of genomic copy number alterations in bladder cancer by microarray-based comparative genomic hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

E2F3 amplification and overexpression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Promoter hypermethylation is associated with tumor location, stage, and subsequent progression in transitional cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Minimal deletion of 3p13-->14.2 associated with immortalization of human uroepithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Loss of FHIT expression in transitional cell carcinoma of the urinary bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Overcoming cellular senescence in human cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

PTCH gene mutations in invasive transitional cell carcinoma of the bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Alteration of the PATCHED locus in superficial bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

A novel candidate tumour suppressor locus at 9q32-33 in bladder cancer: localization of the candidate region within a single 840 kb YAC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Human bladder tumors with 2-hit mutations of tumor suppressor gene TSC1 and decreased expression of p27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Somatic mutation of PTEN in bladder carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Molecular analysis of PTEN and MXI1 in primary bladder carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Altered expression of the retinoblastoma gene product: prognostic indicator in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Altered Expression of Retinoblastoma Protein and Known Prognostic Variables in Locally Advanced Bladder Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Identification of p53 gene mutations in bladder cancers and urine samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Deletion mapping of chromosome 11 in carcinoma of the bladder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Patterns of chromosomal imbalances in advanced urinary bladder cancer detected by comparative genomic hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Identification of gains and losses of DNA sequences in primary bladder cancer by comparative genomic hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Bladder cancer stage and outcome by array-based comparative genomic hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Multiple mechanisms downregulate CDKN1C in human bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Detection of bladder cancer in urine by a tumor suppressor gene hypermethylation panel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Initiation-development modelling of allelic losses on chromosome 9 in multifocal bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Structure and methylation-based silencing of a gene (DBCCR1) within a candidate bladder cancer tumor suppressor region at 9q32-q33.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Superimposed histologic and genetic mapping of chromosome 9 in progression of human urinary bladder neoplasia: implications for a genetic model of multistep urothelial carcinogenesis and early detection of urinary bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Bladder neoplasms--regions at chromosome 9 with putative tumour suppressor genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

A sequence-ready 840-kb PAC contig spanning the candidate tumor suppressor locus DBC1 on human chromosome 9q32-q33.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Comprehensive analysis of CDKN2A status in microdissected urothelial cell carcinoma reveals potential haploinsufficiency, a high frequency of homozygous co-deletion and associations with clinical phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

The INK4a/ARF locus in murine tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

DBCCR1 mediates death in cultured bladder tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Negative regulation of G(1)/S transition by the candidate bladder tumour suppressor gene DBCCR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

United at last: the tuberous sclerosis complex gene products connect the phosphoinositide 3-kinase/Akt pathway to mammalian target of rapamycin (mTOR) signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Frequency of fibroblast growth factor receptor 3 mutations in sporadic tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

An immunohistological demonstration of c-erbB-2 oncoprotein expression in primary urothelial bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

The epidermal growth factor receptor and the prognosis of bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Profiling the evolution of human metastatic bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Overexpression of normal and mutated forms of HRAS induces orthotopic bladder invasion in a human transitional cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

The RB and p53 pathways in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

The IARC TP53 database: new online mutation analysis and recommendations to users

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Accumulation of nuclear p53 and tumor progression in bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

p53 immunohistochemistry as a prognostic marker in bladder cancer. Playground for urology scientists?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Combined effects of p53, p21, and pRb expression in the progression of bladder transitional cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

p53, p21, pRB, and p16 expression predict clinical outcome in cystectomy with bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

The p53 pathway: positive and negative feedback loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Inactivation of MMAC1 in bladder transitional-cell carcinoma cell lines and specimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

PTEN can inhibit in vitro organotypic and in vivo orthotopic invasion of human bladder cancer cells even in the absence of its lipid phosphatase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

In vivo gene therapy of human bladder cancer with PTEN suppresses tumor growth, downregulates phosphorylated Akt, and increases sensitivity to doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

The phosphatidylinositol-3 kinase pathway regulates bladder cancer cell invasion

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Identification of chromosome 9 alterations and p53 accumulation in isolated carcinoma in situ of the urinary bladder versus carcinoma in situ associated with carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Activities of MAP-kinase pathways in normal uroepithelial cells and urothelial carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Clonality of multifocal urothelial carcinomas: 10 years of molecular genetic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Pathways of urothelial cancer progression suggested by Bayesian network analysis of allelotyping data

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Statistical behavior of complex cancer karyotypes

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Gene discovery in bladder cancer progression using cDNA microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Identifying superficial, muscle-invasive, and metastasizing transitional cell carcinoma of the bladder: use of cDNA array analysis of gene expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Bladder cancer outcome and subtype classification by gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Molecular analysis of transitional cell carcinoma using cDNA microarray.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Identifying distinct classes of bladder carcinoma using microarrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Gene expression profiling of progressive papillary noninvasive carcinomas of the urinary bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

The incidence of thanatophoric dysplasia mutations in FGFR3 gene is higher in low-grade or superficial bladder carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Mutations in TP53, but not FGFR3, in urothelial cell carcinoma of the bladder are influenced by smoking: contribution of exogenous versus endogenous carcinogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MIB-1 is superior to pathologic grade for the prediction of clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Deletion of the p16 and p15 Genes in Human Bladder Tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

FGFR3 and Tp53 Mutations in T1G3 Transitional Bladder Carcinomas: Independent Distribution and Lack of Association with Prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

Loss of genes on the short arm of chromosome 11 in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI310

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGI310

1 reference

13 August 2017

1 reference

PubMed ID

16352616