TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma. (Q36339786)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996328%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma (English)

1 reference

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13 February 2020

1 reference

6

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13 February 2020

9

Rakesh K Jain

1 reference

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13 February 2020

5

Shom Goel

1 reference

13 February 2020

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Benjamin Diop-Frimpong

3

object named as

Benjamin Diop-Frimpong

1 reference

13 February 2020

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7

Marek Ancukiewicz

1 reference

13 February 2020

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Jieqiong Liu

1

1 reference

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13 February 2020

Shan Liao

2

1 reference

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13 February 2020

Wei Chen

4

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13 February 2020

Yves Boucher

8

1 reference

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13 February 2020

Lei Xu

10

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13 February 2020

language of work or name

English

0 references

publication date

20 September 2012

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

13 February 2020

published in

1 reference

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13 February 2020

volume

109

1 reference

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13 February 2020

issue

41

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13 February 2020

page(s)

16618-16623

1 reference

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Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

13 February 2020

cites work

1 reference

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Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

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Normalization of the vasculature for treatment of cancer and other diseases

30 September 2017

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Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors

30 September 2017

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TGF-beta blockade controls ascites by preventing abnormalization of lymphatic vessels in orthotopic human ovarian carcinoma models

30 September 2017

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TGF-beta biology in mammary development and breast cancer

30 September 2017

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Stromal regulation of vessel stability by MMP14 and TGFbeta

30 September 2017

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Anti-transforming growth factor beta receptor II antibody has therapeutic efficacy against primary tumor growth and metastasis through multieffects on cancer, stroma, and immune cells

30 September 2017

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30 September 2017

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An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments.

30 September 2017

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Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling.

30 September 2017

1 reference

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Ki26894, a novel transforming growth factor-beta type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line.

30 September 2017

1 reference

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TGF beta inhibition for cancer therapy

30 September 2017

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Transforming growth factor-beta in cancer and metastasis

30 September 2017

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Intraperitoneal immunotherapy for metastatic ovarian carcinoma: Resistance of intratumoral collagen to antibody penetration.

30 September 2017

1 reference

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Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells

30 September 2017

1 reference

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Delivery of viral vectors to tumor cells: extracellular transport, systemic distribution, and strategies for improvement

30 September 2017

1 reference

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The penetration of anticancer drugs through tumor tissue as a function of cellular adhesion and packing density of tumor cells

30 September 2017

1 reference

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Proprotein convertases: "master switches" in the regulation of tumor growth and progression

30 September 2017

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Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

30 September 2017

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Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors

30 September 2017

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Synthesis and activity of new aryl- and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain

30 September 2017

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Molecular regulation of vessel maturation

30 September 2017

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Increased furin activity enhances the malignant phenotype of human head and neck cancer cells

30 September 2017

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Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

30 September 2017

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Extracellular domain of TGFbeta type III receptor inhibits angiogenesis and tumor growth in human cancer cells

30 September 2017

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Processing of immunosuppressive pro-TGF-beta 1,2 by human glioblastoma cells involves cytoplasmic and secreted furin-like proteases

30 September 2017

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Role of tumor-host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors.

30 September 2017

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30 September 2017

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Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent

30 September 2017

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30 September 2017

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Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

30 September 2017

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The next frontier of molecular medicine: delivery of therapeutics.

30 September 2017

1 reference

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Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size.

29 June 2018

1 reference

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Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vector

22 September 2018

1 reference

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IL-3 affects endothelial cell-mediated smooth muscle cell recruitment by increasing TGF beta activity: potential role in tumor vessel stabilization.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478596

Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478596

Available space and extracellular transport of macromolecules: effects of pore size and connectedness

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478596

Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor.

22 September 2018

1 reference

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Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1117610109

PDGF and TGF-beta mediate collagen production by mesangial cells exposed to advanced glycosylation end products

21 January 2018

1 reference

12 December 2020

Systemic administration of a soluble betaglycan suppresses tumor growth, angiogenesis, and matrix metalloproteinase-9 expression in a human xenograft model of prostate cancer

1 reference

12 December 2020

Inhibition of TGF-beta modulates macrophages and vessel maturation in parallel to a lowering of interstitial fluid pressure in experimental carcinoma

1 reference

12 December 2020

Transforming growth factor-beta promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1

1 reference

12 December 2020

Role of extracellular matrix assembly in interstitial transport in solid tumors

1 reference

12 December 2020

Enhancement of paclitaxel delivery to solid tumors by apoptosis-inducing pretreatment: effect of treatment schedule

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12 December 2020

Clinical aspects of drug delivery to tumors

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1117610109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996328%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996328%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996328%20AND%20SRC:MED&resulttype=core&format=json