Molecular pathogenesis of alcohol-induced hepatic fibrosis (Q36339556)

13 August 2017

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title

Molecular pathogenesis of alcohol-induced hepatic fibrosis (English)

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13 August 2017

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David A Brenner

2

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author name string

Sören V Siegmund

series ordinal

1

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13 August 2017

1 November 2005

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Alcoholism: Clinical and Experimental Research

13 August 2017

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13 August 2017

29

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13 August 2017

11 Suppl

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13 August 2017

102S-109S

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Coordinated induction of VEGF receptors in mesenchymal cell types during rat hepatic wound healing

13 August 2017

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Reversibility of liver fibrosis and cirrhosis following treatment for hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

CCAAT/enhancer binding protein beta mediates the activation of the murine alpha1(I) collagen promoter by acetaldehyde

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Identification of new sites of binding and activation of the murine alpha1(I) collagen promoter by CCAAT/enhancer binding protein beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Hepatic stellate cells as a target for the treatment of liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Impact of alcohol on the ability of Kupffer cells to produce chemokines and its role in alcoholic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Extracellular matrix degradation and the role of hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Progelatinase A is produced and activated by rat hepatic stellate cells and promotes their proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

New aspects of hepatic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Gliotoxin ameliorates development of fibrosis and cirrhosis in a thioacetamide rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Liver fibrosis -- from bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Transforming growth factor beta1 induces the expression of alpha1(I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta-dependent mechanism in rat hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Hydrogen peroxide: a link between acetaldehyde-elicited alpha1(I) collagen gene up-regulation and oxidative stress in mouse hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Hepatic stellate cell behavior during resolution of liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Mechanisms of inflammatory liver injury: adhesion molecules and cytotoxicity of neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Malondialdehyde-acetaldehyde-protein adducts increase secretion of chemokines by rat hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Gliotoxin-mediated apoptosis of activated human hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Ethanol metabolism, cirrhosis and alcoholism

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Regulation of alpha1(I) collagen messenger RNA decay by interactions with alphaCP at the 3'-untranslated region

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Interactions between hepatic stellate cells and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Ethanol and arachidonic acid increase alpha 2(I) collagen expression in rat hepatic stellate cells overexpressing cytochrome P450 2E1. Role of H2O2 and cyclooxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Molecular mechanism of the reversibility of hepatic fibrosis: with special reference to the role of matrix metalloproteinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Aldehydic products of lipid peroxidation do not directly activate rat hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Histological course of alcoholic hepatitis. Influence of abstinence, sex and extent of hepatic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Anandamide induces necrosis in primary hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

5' stem-loop of collagen alpha 1(I) mRNA inhibits translation in vitro but is required for triple helical collagen synthesis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Alterations in hepatic lipids and proteins by chronic ethanol intake: a high-pressure Fourier transform infrared spectroscopic study on alcoholic liver disease in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Malondialdehyde-acetaldehyde (MAA) modified proteins induce pro-inflammatory and pro-fibrotic responses by liver endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Immunologic mechanisms of alcoholic liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Current concepts in the pathogenesis of alcoholic liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

The role of Kupffer cell oxidant production in early ethanol-induced liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Delivery of the Cu/Zn-superoxide dismutase gene with adenovirus reduces early alcohol-induced liver injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Overexpression of manganese superoxide dismutase prevents alcohol-induced liver injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.ALC.0000189275.97419.58

10.1097/01.ALC.0000189275.97419.58

21 January 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference

PubMed ID

16344593