Therapeutic potential of a monoclonal antibody blocking the Wnt pathway in diabetic retinopathy (Q36339514)

13 August 2017

Therapeutic potential of a monoclonal antibody blocking the Wnt pathway in diabetic retinopathy (English)

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13 August 2017

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Kyungwon Lee

1

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13 August 2017

Yang Hu

2

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13 August 2017

Lexi Ding

3

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13 August 2017

Ying Chen

4

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13 August 2017

Yusuke Takahashi

5

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13 August 2017

Robert Mott

6

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13 August 2017

Jian-Xing Ma

7

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13 August 2017

language of work or name

English

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publication date

13 August 2012

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13 August 2017

10

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inferred from page(s)

published in

Diabetes

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13 August 2017

61

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13 August 2017

11

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13 August 2017

2948-2957

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

13 August 2017

start time

30 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3478529/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The role of lipid peroxidation products and oxidative stress in activation of the canonical wingless-type MMTV integration site (WNT) pathway in a rat model of diabetic retinopathy

30 September 2017

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Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies

30 September 2017

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Blocking the Wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family

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Inhibition of connective tissue growth factor overexpression in diabetic retinopathy by SERPINA3K via blocking the WNT/beta-catenin pathway.

30 September 2017

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Activation of the Wnt pathway plays a pathogenic role in diabetic retinopathy in humans and animal models

30 September 2017

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Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema

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Oxidative stress and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives

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IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

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30 September 2017

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Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy.

30 September 2017

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Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

30 September 2017

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Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling

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Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization

30 September 2017

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Wnt/Frizzled signaling in the vasculature: new angiogenic factors in sight

30 September 2017

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A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

30 September 2017

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Old and new drug targets in diabetic retinopathy: from biochemical changes to inflammation and neurodegeneration

30 September 2017

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30 September 2017

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30 September 2017

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beta-Catenin regulates vascular endothelial growth factor expression in colon cancer

30 September 2017

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Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

30 September 2017

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Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

30 September 2017

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Sensitive blood-retinal barrier breakdown quantitation using Evans blue

30 September 2017

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Regulators of vascular permeability: potential sites for intervention in the treatment of macular edema

30 September 2017

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Vascular endothelial growth factor in ocular neovascularization and proliferative diabetic retinopathy.

30 September 2017

1 reference

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Difference in ischemic regulation of vascular endothelial growth factor and pigment epithelium--derived factor in brown norway and sprague dawley rats contributing to different susceptibilities to retinal neovascularization

30 September 2017

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Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia

29 June 2018

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Frizzled 4 is required for retinal angiogenesis and maintenance of the blood-retina barrier.

29 June 2018

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Eyeing up new Wnt pathway players

22 September 2018

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A central role for inflammation in the pathogenesis of diabetic retinopathy

22 September 2018

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Connective tissue growth factor is up-regulated in the diabetic retina: amelioration by angiotensin-converting enzyme inhibition

22 September 2018

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Diabetic retinopathy. Pathophysiology and therapy of hypoxia-induced inflammation

22 September 2018

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22 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891217

12 December 2020

inferred from PubMed ID database lookup

Oxygen-induced retinopathy in the mouse

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22891217

12 December 2020

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891217

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.2337/DB11-0300

1 reference

13 August 2017

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13 August 2017

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