Microsatellite instability in gastrointestinal tract cancers: a brief update (Q36338134)

13 August 2017

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title

Microsatellite instability in gastrointestinal tract cancers: a brief update (English)

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13 August 2017

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3

Yoshihiko Maehara

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13 August 2017

Shinya Oda

1

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PubMed ID

16341479

13 August 2017

Yan Zhao

series ordinal

2

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13 August 2017

1 January 2005

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13 August 2017

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13 August 2017

35

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13 August 2017

12

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13 August 2017

1005-1015

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The instability within: problems in current analyses of microsatellite instability

13 August 2017

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https://api.crossref.org/works/10.1007%2FS00595-005-3125-1

Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-005-3125-1

Histopathological identification of colon cancer with microsatellite instability

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-005-3125-1

Genetic and epigenetic modification of MLH1 accounts for a major share of microsatellite-unstable colorectal cancers

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-005-3125-1

Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-005-3125-1

Microsatellite instability in gastric intestinal metaplasia in patients with and without gastric cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-005-3125-1

Frequent microsatellite instabilities and analyses of the related genes in familial gastric cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-005-3125-1

Microsatellite instability in squamous cell carcinoma of the head and neck.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-005-3125-1

Infrequent microsatellite instability in oesophageal cancers

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-005-3125-1

Infrequent replication errors at microsatellite loci in tumors of patients with multiple primary cancers of the esophagus and various other tissues.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-005-3125-1

Genetic alterations in Barrett esophagus and adenocarcinomas of the esophagus and esophagogastric junction region

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-005-3125-1

Microsatellite Instability and hMLH1 and hMSH2 expression analysis in familial and sporadic colorectal cancer

21 January 2018

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12 December 2020

The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas

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12 December 2020

Correspondence re: P. Laiho et al., Low-level microsatellite instability in most colorectal carcinomas. Cancer Res., 62: 1166-1170, 2002

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12 December 2020

A mutator phenotype in cancer.

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12 December 2020

Microsatellite instability as a tool for the classification of gastric cancer

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12 December 2020

Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families

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12 December 2020

Frequency of microsatellite instability inBreast cancer determined by high-resolution fluorescent microsatellite analysis

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12 December 2020

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

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12 December 2020

E-cadherin germline mutations in familial gastric cancer.

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12 December 2020

Mismatch repair and microsatellite instability in esophageal cancer cells.

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12 December 2020

Comparison of selection strategies for genetic testing of patients with hereditary nonpolyposis colorectal carcinoma: effectiveness and cost-effectiveness

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12 December 2020

High frequency of microsatellite instability in young patients with head-and-neck squamous-cell carcinoma: lack of involvement of the mismatch repair genes hMLH1 AND hMSH2.

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12 December 2020

Prognostic value and clinicopathological profile of microsatellite instability in gastric cancer.

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12 December 2020

Microsatellite-stable diploid carcinoma: a biologically distinct and aggressive subset of sporadic colorectal cancer

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12 December 2020

Frequent co-occurrence of mutator phenotype in synchronous, independent multiple cancers of the stomach

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12 December 2020

Frequency of hereditary nonpolyposis colorectal cancer. A prospective multicenter study in Finland.

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12 December 2020

Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer

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12 December 2020

Correlation of mismatch repair genes immunohistochemistry and microsatellite instability status in HNPCC-associated tumours

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12 December 2020

Red meat, family history, and increased risk of gastric cancer with microsatellite instability.

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12 December 2020

Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer

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12 December 2020

p53 Gene mutation and genetic instability in superficial multifocal esophageal squamous cell carcinoma

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12 December 2020

Genetic instability occurs in the majority of young patients with colorectal cancer

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12 December 2020

Molecular mechanisms involved in the pathogenesis of gastric carcinoma: interactions between genetic alterations, cellular phenotype and cancer histotype.

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12 December 2020

Emerging concepts in colorectal neoplasia

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12 December 2020

RER phenotype and its associated mutations in familial gastric cancer

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12 December 2020

Multiple mutations and cancer

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12 December 2020

Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences.

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12 December 2020

Familial gastric cancer: overview and guidelines for management

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12 December 2020

Frequent loss of heterozygosity but rare microsatellite instability in oesophageal cancer in Japanese and Chinese patients.

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12 December 2020

Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator phenotype

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12 December 2020

Morphology of sporadic colorectal cancer with DNA replication errors

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12 December 2020

Features of gastric cancer in hereditary non-polyposis colorectal cancer syndrome

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12 December 2020

Differential involvement of the hypermethylator phenotype in hereditary and sporadic colorectal cancers with high-frequency microsatellite instability.

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12 December 2020

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer

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12 December 2020

New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.

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12 December 2020

Genetic tumor markers with prognostic impact in Dukes' stages B and C colorectal cancer patients

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12 December 2020

Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype

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12 December 2020

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

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12 December 2020

Detection of head and neck squamous cell carcinoma among exfoliated oral mucosal cells by microsatellite analysis

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12 December 2020

A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor

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12 December 2020

Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

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12 December 2020

Antibody-based screening for hereditary nonpolyposis colorectal carcinoma compared with microsatellite analysis and sequencing.

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12 December 2020

The mutation rate and cancer

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12 December 2020

Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait

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12 December 2020

Distinct clinical features and outcomes of gastric cancers with microsatellite instability

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12 December 2020

Detection of loss of heterozygosity by high-resolution fluorescent system in non-small cell lung cancer: association of loss of heterozygosity with smoking and tumor progression.

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12 December 2020

Clues to the pathogenesis of familial colorectal cancer

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12 December 2020

Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines

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12 December 2020

Genomic DNA-based hMSH2 and hMLH1 mutation screening in 32 Eastern United States hereditary nonpolyposis colorectal cancer pedigrees

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12 December 2020

Characterization of sporadic colon cancer by patterns of genomic instability.

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12 December 2020

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

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12 December 2020

Infrequent frameshift mutations of polynucleotide repeats in multiple primary cancers affecting the esophagus and other organs.

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12 December 2020

Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancers

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12 December 2020

Genetic instabilities in human cancers

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12 December 2020

Ubiquitous somatic alterations at microsatellite alleles occur infrequently in Barrett's-associated esophageal adenocarcinoma

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12 December 2020

Microsatellite instability in cancer: what problems remain unanswered?

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12 December 2020

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

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12 December 2020

Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer

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12 December 2020

High frequency of low-level microsatellite instability in early colorectal cancer.

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12 December 2020

Cancer of the microsatellite mutator phenotype.

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12 December 2020

Microsatellite instability in cancer of the proximal colon

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12 December 2020

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways

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12 December 2020

Microsatellite instability in sporadic mucinous colorectal carcinomas: relationship to clinico-pathological variables.

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12 December 2020

Characterization of MSH2 and MLH1 mutations in Italian families with hereditary nonpolyposis colorectal cancer

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12 December 2020

Extensive methylation of hMLH1 promoter region predominates in proximal colon cancer with microsatellite instability.

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12 December 2020

Germline mutations of hMLH1 and hMSH2 genes in Korean hereditary nonpolyposis colorectal cancer

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12 December 2020

Precise assessment of microsatellite instability using high resolution fluorescent microsatellite analysis

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12 December 2020

Colorectal carcinoma associated with serrated adenoma--prevalence, histological features, and prognosis

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12 December 2020

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

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12 December 2020

Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer.

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12 December 2020

Mutation screening in the hMLH1 gene in Swedish hereditary nonpolyposis colon cancer families

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12 December 2020

Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level.

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12 December 2020

Mucin phenotype and microsatellite instability in early multiple gastric cancers

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12 December 2020

Microsatellite instability in synchronous gastric carcinomas.

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12 December 2020

Microsatellite instability in gastrointestinal tract tumours.

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12 December 2020

Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog

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12 December 2020

Microsatellite instability is a genetic marker for the development of multiple gastric cancers

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12 December 2020

Genetic classification of colorectal cancer based on chromosomal loss and microsatellite instability predicts survival

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12 December 2020

Genetic instability in colorectal cancers

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12 December 2020

Low-level microsatellite instability in most colorectal carcinomas

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12 December 2020

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

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12 December 2020

Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

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12 December 2020

Methylation of the hMLH1 promoter in familial gastric cancer with microsatellite instability

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12 December 2020

Molecular Screening for Hereditary Nonpolyposis Colorectal Cancer: A Prospective, Population-Based Study

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12 December 2020

Mutated gene-specific phenotypes of dinucleotide repeat instability in human colorectal carcinoma cell lines deficient in DNA mismatch repair

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12 December 2020

Microsatellite instability and loss of heterozygosity in gastric carcinoma in comparison to family history

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12 December 2020

Microsatellite instability in gastric cancer is associated with tumor location and family history in a high-risk population from Tuscany.

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12 December 2020

Stage-dependent evaluation of microsatellite instability in gastric carcinoma with familial clustering

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12 December 2020

The clinical importance and prognostic implications of microsatellite instability in sporadic cancer

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12 December 2020

Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas

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12 December 2020

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

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12 December 2020

Features of microsatellite instability in colorectal cancer: comparison between colon and rectum.

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12 December 2020

Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors

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12 December 2020

Alternative genetic pathways in colorectal carcinogenesis.

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12 December 2020

Microsatellite instability in adenocarcinomas of the upper gastrointestinal tract. Relation to clinicopathological data and family history

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12 December 2020

Methylation pattern of different regions of theMLH1 promoter and silencing of gene expression in hereditary and sporadic colorectal cancer

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12 December 2020

Microsatellite instability, prognosis and metastasis in gastric cancers from a low-risk population

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12 December 2020

Microsatellite instability in human solid tumors

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12 December 2020

Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia.

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12 December 2020

Marked differences in the frequency of microsatellite instability in gastric cancer from different countries

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12 December 2020

Frameshift-mutation-derived peptides as tumor-specific antigens in inherited and spontaneous colorectal cancer

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12 December 2020

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

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12 December 2020

Microsatellite instability: the mutator that mutates the other mutator

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12 December 2020

Frequent microsatellite alterations on chromosome 3p in esophageal squamous cell carcinoma

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12 December 2020

Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability

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12 December 2020

Progression of microsatellite instability from premalignant lesions to tumors of the head and neck

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12 December 2020

Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer

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12 December 2020

10.1007/S00595-005-3125-1

Identifiers

DOI

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13 August 2017

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PubMed ID

16341479