In situ biochemical demonstration that P-glycoprotein is a drug efflux pump with broad specificity. (Q36326998)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10704438%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

In situ biochemical demonstration that P-glycoprotein is a drug efflux pump with broad specificity (English)

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4 November 2019

2

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4 November 2019

author name string

Y Chen

series ordinal

1

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4 November 2019

language of work or name

English

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publication date

1 March 2000

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4 November 2019

number of pages

8

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based on heuristic

inferred from page(s)

published in

Journal of Cell Biology

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4 November 2019

volume

148

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4 November 2019

page(s)

863-870

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4 November 2019

issue

5

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Mechanism of action of P-glycoprotein in relation to passive membrane permeation.

4 November 2019

cites work

1 reference

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Tamoxifen inhibits acidification in cells independent of the estrogen receptor

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The green fluorescent protein

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Defective acidification in human breast tumor cells and implications for chemotherapy.

30 September 2017

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Human MDR 1 protein overexpression delays the apoptotic cascade in Chinese hamster ovary fibroblasts.

30 September 2017

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30 September 2017

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Are altered pHi and membrane potential in hu MDR 1 transfectants sufficient to cause MDR protein-mediated multidrug resistance?

30 September 2017

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Defective pH regulation of acidic compartments in human breast cancer cells (MCF-7) is normalized in adriamycin-resistant cells (MCF-7adr).

30 September 2017

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Kinetics of plasma membrane and mitochondrial alterations in cells undergoing apoptosis

30 September 2017

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Intracellular pH and the control of multidrug resistance

30 September 2017

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Biochemistry of multidrug resistance mediated by the multidrug transporter

30 September 2017

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Cell biological mechanisms of multidrug resistance in tumors

30 September 2017

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The multidrug resistance (mdr1) gene product functions as an ATP channel

30 September 2017

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Evaluation of multidrug resistant phenotype by flow cytometry with monoclonal antibodies and functional tests.

30 September 2017

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Rapid and efficient site-specific mutagenesis without phenotypic selection

30 September 2017

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A flow-cytometric method for the separation and quantitation of normal and apoptotic thymocytes

30 September 2017

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Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein

30 September 2017

1 reference

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Pleiotropic phenotype of colchicine-resistant CHO cells: cross-resistance and collateral sensitivity

30 September 2017

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Kinetics of the multidrug transporter (P-glycoprotein) and its reversal

30 September 2017

1 reference

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Biophysical aspects of P-glycoprotein-mediated multidrug resistance.

30 September 2017

1 reference

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Expression-activity profiles of cells transfected with prostaglandin endoperoxide H synthase measured by quantitative fluorescence microscopy

30 September 2017

1 reference

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Fluorescent cellular indicators are extruded by the multidrug resistance protein.

30 September 2017

1 reference

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Multifactorial resistance to adriamycin: relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of adriamycin-sensitive and -resistant P388 leukemia.

29 June 2018

1 reference

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Activity of the multidrug transporter results in alkalinization of the cytosol: measurement of cytosolic pH by microinjection of a pH-sensitive dye

29 June 2018

1 reference

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Membrane-Mediated Drug Resistance and Phenotypic Reversion to Normal Growth Behavior of Chinese Hamster Cells 2

29 June 2018

1 reference

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Increased cytosolic pH in multidrug-resistant human lung tumor cells: effect of verapamil.

29 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.148.5.863

Lower electrical membrane potential and altered pHi homeostasis in multidrug-resistant (MDR) cells: further characterization of a series of MDR cell lines expressing different levels of P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.148.5.863

Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.148.5.863

Kinetic parameters for reversal of the multidrug pump as measured for drug accumulation and cell killing

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.148.5.863

21 January 2018

Identifiers

DOI

10.1083/JCB.148.5.863

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10704438%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10704438%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference