A Perspective on Roles Played by Innate and Adaptive Immunity in the Pathobiology of Neurodegenerative Disorders (Q36326816)

13 August 2017

A Perspective on Roles Played by Innate and Adaptive Immunity in the Pathobiology of Neurodegenerative Disorders (English)

1 reference

13 August 2017

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1

Howard E Gendelman

1 reference

13 August 2017

R Lee Mosley

2

1 reference

13 August 2017

31 October 2015

1 reference

Journal of Neuroimmune Pharmacology

13 August 2017

1 reference

13 August 2017

10

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13 August 2017

645-650

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13 August 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1007/s11481-015-9639-4

13 August 2017

0 references

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Role of Circulating Immune Cells in Stroke and Preconditioning-Induced Protection

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Microglial malfunction: the third rail in the development of Alzheimer's disease

30 September 2017

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Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic mice

30 September 2017

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Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology

30 September 2017

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Therapeutic effects of glatiramer acetate and grafted CD115⁺ monocytes in a mouse model of Alzheimer's disease.

30 September 2017

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Review: an update on clinical, genetic and pathological aspects of frontotemporal lobar degenerations.

30 September 2017

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Cerebral amyloid angiopathy: emerging concepts

30 September 2017

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Innate immunity in Alzheimer's disease

30 September 2017

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Neuroinflammation in Alzheimer's disease

30 September 2017

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Dual destructive and protective roles of adaptive immunity in neurodegenerative disorders

30 September 2017

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Role of α-synuclein in inducing innate and adaptive immunity in Parkinson disease.

30 September 2017

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Protective and Toxic Neuroinflammation in Amyotrophic Lateral Sclerosis

30 September 2017

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Partial suppression of M1 microglia by Janus kinase 2 inhibitor does not protect against neurodegeneration in animal models of amyotrophic lateral sclerosis.

30 September 2017

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Neuroinflammation in Alzheimer's disease; A source of heterogeneity and target for personalized therapy

30 September 2017

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Breaking peripheral immune tolerance to CNS antigens in neurodegenerative diseases: boosting autoimmunity to fight-off chronic neuroinflammation.

30 September 2017

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Common mechanisms of Alzheimer's disease and ischemic stroke: the role of protein kinase C in the progression of age-related neurodegeneration

30 September 2017

1 reference

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Evidence of inflammatory system involvement in Parkinson's disease

30 September 2017

1 reference

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Immunosenescence, inflammation and Alzheimer's disease

30 September 2017

1 reference

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Regulation of neurotropic signaling by the inducible, NF-kB-sensitive miRNA-125b in Alzheimer's disease (AD) and in primary human neuronal-glial (HNG) cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Spinal but not cortical microglia acquire an atypical phenotype with high VEGF, galectin-3 and osteopontin, and blunted inflammatory responses in ALS rats

30 September 2017

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The immune system and aging: a review.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxicated mice

30 September 2017

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Systemic transplantation of human umbilical cord derived mesenchymal stem cells-educated T regulatory cells improved the impaired cognition in AβPPswe/PS1dE9 transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Immune-mediated mechanisms in the pathoprogression of amyotrophic lateral sclerosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Proinflammatory cytokines, aging, and age-related diseases

30 September 2017

1 reference

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The role of inflammation in sporadic and familial Parkinson's disease

30 September 2017

1 reference

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Inflammation and neurovascular changes in amyotrophic lateral sclerosis.

30 September 2017

1 reference

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CD4+ regulatory and effector/memory T cell subsets profile motor dysfunction in Parkinson's disease

30 September 2017

1 reference

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Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS.

30 September 2017

1 reference

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Inflammation and adaptive immunity in Parkinson's disease

30 September 2017

1 reference

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SOD mimetics: a novel class of androgen receptor inhibitors that suppresses castration-resistant growth of prostate cancer

30 September 2017

1 reference

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Immunization strategies for Parkinson's disease

30 September 2017

1 reference

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Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology

30 September 2017

1 reference

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Pathways towards an effective immunotherapy for Parkinson's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis

30 September 2017

1 reference

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Amyotrophic lateral sclerosis pathogenesis: a journey through the secretory pathway.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Immune-inflammatory responses and oxidative stress in Alzheimer's disease: therapeutic implications

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Low grade inflammation as a common pathogenetic denominator in age-related diseases: novel drug targets for anti-ageing strategies and successful ageing achievement.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Control of neuroinflammation as a therapeutic strategy for amyotrophic lateral sclerosis and other neurodegenerative disorders

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Microglia in ALS: the good, the bad, and the resting

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Proteomic studies of nitrated alpha-synuclein microglia regulation by CD4+CD25+ T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Pathophysiology of neurodegeneration in familial amyotrophic lateral sclerosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsets

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Progress in the active immunotherapeutic approach to Alzheimer's disease: clinical investigations into AN1792-associated meningoencephalitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Oxidative stress and the pathogenesis of neurodegenerative disorders

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Prototype Alzheimer's disease epitope vaccine induced strong Th2-type anti-Abeta antibody response with Alum to Quil A adjuvant switch

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Emerging mechanisms of molecular pathology in ALS.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Circulating brain derived neurotrophic factor (BDNF) and frequency of BDNF positive T cells in peripheral blood in human ischemic stroke: Effect on outcome.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

[American Academy of Neurology, Washington, 18-25 April 2015].

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Letter by Gauberti and Vivien regarding article, "amplification of regulatory T cells using a CD28 superagonist reduces brain damage after ischemic stroke in mice".

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Response to letter regarding article, "amplification of regulatory T cells using a CD28 superagonist reduces brain damage after ischemic stroke in mice".

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Amplification of regulatory T cells using a CD28 superagonist reduces brain damage after ischemic stroke in mice.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Biomarker-based predictive models for prognosis in amyotrophic lateral sclerosis

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Parkinson disease: from pathology to molecular disease mechanisms.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Neuroinflammation, Oxidative Stress and the Pathogenesis of Parkinson's Disease

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662620

Protective autoimmunity in the nervous system

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11481-015-9639-4

Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11481-015-9639-4

PD1 Negative and PD1 Positive CD4+ T Regulatory Cells in Mild Cognitive Impairment and Alzheimer's Disease

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11481-015-9639-4

MHC-independent genetic factors control the magnitude of CD4+ T cell responses to amyloid-β peptide in mice through regulatory T cell-mediated inhibition

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26520433

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11481-015-9639-4

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

PMCID

4662620