Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition. (Q36314000)

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English	Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition.	scientific article

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8 January 2020

Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition (English)

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8 January 2020

Streptococcus pneumoniae

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Michelle Darrieux

1

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8 January 2020

Eliane N Miyaji

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8 January 2020

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8 January 2020

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D M Ferreira

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8 January 2020

L M Lopes

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8 January 2020

A P Y Lopes

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8 January 2020

B Ren

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8 January 2020

D E Briles

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8 January 2020

S K Hollingshead

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8 January 2020

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8 October 2007

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8 January 2020

Infection and Immunity

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75

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8 January 2020

12

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8 January 2020

5930-5938

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8 January 2020

Streptococcus pneumoniae protein vaccine candidates: properties, activities and animal studies

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Genetic diversity of PspA types among nasopharyngeal isolates collected during an ongoing surveillance study of children in Brazil

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30 September 2017

Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface

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30 September 2017

Complement resistance mechanisms of streptococci

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30 September 2017

Relative roles of genetic background and variation in PspA in the ability of antibodies to PspA to protect against capsular type 3 and 4 strains of Streptococcus pneumoniae

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30 September 2017

Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae

1 reference

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30 September 2017

The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice

1 reference

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30 September 2017

Analysis of serum cross-reactivity and cross-protection elicited by immunization with DNA vaccines against Streptococcus pneumoniae expressing PspA fragments from different clades.

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30 September 2017

Pneumococcal pspA sequence types of prevalent multiresistant pneumococcal strains in the United States and of internationally disseminated clones

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30 September 2017

Diversity of PspA: mosaic genes and evidence for past recombination in Streptococcus pneumoniae

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Killing of Streptococcus pneumoniae by capsular polysaccharide-specific polymeric IgA, complement, and phagocytes

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Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae.

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Adoptive transfer of immunity to oral challenge with virulent salmonellae in innately susceptible BALB/c mice requires both immune serum and T cells

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Novel surface attachment mechanism of the Streptococcus pneumoniae protein PspA

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30 September 2017

Localization of protection-eliciting epitopes on PspA of Streptococcus pneumoniae between amino acid residues 192 and 260.

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30 September 2017

Truncated forms of PspA that are secreted from Streptococcus pneumoniae and their use in functional studies and cloning of the pspA gene

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30 September 2017

Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis

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30 September 2017

Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae

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30 September 2017

Pneumococcal surface protein A of invasive Streptococcus pneumoniae isolates from Colombian children

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29 June 2018

Additive inhibition of complement deposition by pneumolysin and PspA facilitates Streptococcus pneumoniae septicemia.

1 reference

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22 September 2018

Typing of pneumococcal surface protein A (PspA) in Streptococcus pneumoniae isolated during epidemiological surveillance in Brazil: towards novel pneumococcal protein vaccines

1 reference

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22 September 2018

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Capsule does not block antibody binding to PspA, a surface virulence protein of Streptococcus pneumoniae

1 reference

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Immunization of humans with recombinant pneumococcal surface protein A (rPspA) elicits antibodies that passively protect mice from fatal infection with Streptococcus pneumoniae bearing heterologous PspA

1 reference

https://pubmed.ncbi.nlm.nih.gov/17923518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epitope analyses of pneumococcal surface protein A: a combination of two monoclonal antibodies detects 94% of clinical isolates

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PspA, a protection-eliciting pneumococcal protein: immunogenicity of isolated native PspA in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17923518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.00940-07

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8 January 2020

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Europe PubMed Central

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8 January 2020

1 reference

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8 January 2020

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