Competitive Inhibition of the Endoplasmic Reticulum Signal Peptidase by Non-cleavable Mutant Preprotein Cargos (Q36301236)

13 August 2017

Competitive Inhibition of the Endoplasmic Reticulum Signal Peptidase by Non-cleavable Mutant Preprotein Cargos (English)

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13 August 2017

endoplasmic reticulum

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Andrew W Tai

9

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author name string

Jingqiu Cui

1

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13 August 2017

Wei Chen

2

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13 August 2017

Jinhong Sun

3

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13 August 2017

Huan Guo

4

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13 August 2017

Rachel Madley

5

1 reference

13 August 2017

Yi Xiong

6

1 reference

13 August 2017

Xingyi Pan

7

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13 August 2017

Hongliang Wang

8

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13 August 2017

Michael A Weiss

10

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13 August 2017

Peter Arvan

11

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13 August 2017

Ming Liu

12

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13 August 2017

language of work or name

English

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publication date

7 October 2015

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Journal of Biological Chemistry

13 August 2017

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13 August 2017

290

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13 August 2017

47

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13 August 2017

28131-28140

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describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4653672/fullTextXML

inferred from PubMed Central ID database lookup

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The catalytic mechanism of endoplasmic reticulum signal peptidase appears to be distinct from most eubacterial signal peptidases

30 September 2017

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Influenza C virus CM2 integral membrane glycoprotein is produced from a polypeptide precursor by cleavage of an internal signal sequence

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30 September 2017

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Possible involvement of inefficient cleavage of preprovasopressin by signal peptidase as a cause for familial central diabetes insipidus

30 September 2017

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Isolation of intracellular membranes by means of sodium carbonate treatment: application to endoplasmic reticulum

30 September 2017

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A mutation downstream from the signal peptidase cleavage site affects cleavage but not membrane insertion of phage coat protein

30 September 2017

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30 September 2017

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30 September 2017

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Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma

30 September 2017

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30 September 2017

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Leader peptidase catalyzes the release of exported proteins from the outer surface of the Escherichia coli plasma membrane.

30 September 2017

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The signal peptide of the mouse mammary tumor virus Rem protein is released from the endoplasmic reticulum membrane and accumulates in nucleoli

29 June 2018

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Folding of HIV-1 envelope glycoprotein involves extensive isomerization of disulfide bonds and conformation-dependent leader peptide cleavage

22 September 2018

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Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras

22 September 2018

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Escherichia coli leader peptidase: production of an active form lacking a requirement for detergent and development of peptide substrates

22 September 2018

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Membrane topology and biogenesis of eukaryotic signal peptidase.

22 September 2018

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Diverse effects of mutations in the signal sequence on the secretion of beta-lactamase in Salmonella typhimurium.

22 September 2018

1 reference

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A signal peptide with a proline next to the cleavage site inhibits leader peptidase when present in a sec -independent protein

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.692350

The HIV-1 Env Protein Signal Sequence Retards Its Cleavage and Down-regulates the Glycoprotein Folding

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.692350

Life and death of a signal peptide

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.692350

Leader peptidase is found in both the inner and outer membranes of Escherichia coli

21 January 2018

1 reference

12 December 2020

Use of site-directed mutagenesis to define the limits of sequence variation tolerated for processing of the M13 procoat protein by the Escherichia coli leader peptidase

1 reference

12 December 2020

Synthesis of precursor maltose-binding protein with proline in the +1 position of the cleavage site interferes with the activity of Escherichia coli signal peptidase I in vivo

1 reference

12 December 2020

Human coagulation factor X deficiency caused by a mutant signal peptide that blocks cleavage by signal peptidase but not targeting and translocation to the endoplasmic reticulum

1 reference

12 December 2020

Determination of the kinetic parameters of Escherichia coli leader peptidase activity using a continuous assay: the pH dependence and time-dependent inhibition by beta-lactams are consistent with a novel serine protease mechanism

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M115.692350

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

26446786

1 reference