Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology (Q36296406)

13 August 2017

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title

Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology (English)

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13 August 2017

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Victor E Marquez

1

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13 August 2017

Joseph J Barchi

2

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13 August 2017

James A Kelley

3

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13 August 2017

Kambhampati V R Rao

4

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13 August 2017

Riad Agbaria

5

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13 August 2017

Tsipi Ben-Kasus

6

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13 August 2017

Jonathan C Cheng

7

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13 August 2017

Christine B Yoo

8

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13 August 2017

Peter A Jones

9

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13 August 2017

language of work or name

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1 January 2005

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Nucleosides, Nucleotides & Nucleic Acids

13 August 2017

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13 August 2017

24

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13 August 2017

5-7

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13 August 2017

305-318

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Inhibition of cytidine deaminase by 2-oxopyrimidine riboside and related compounds.

13 August 2017

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https://api.crossref.org/works/10.1081%2FNCN-200059765

Antitumor properties of 2(1H)-pyrimidinone riboside (zebularine) and its fluorinated analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FNCN-200059765

Enzyme-substrate complexes of adenosine and cytidine deaminases: absence of accumulation of water adducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FNCN-200059765

Cyclic urea nucleosides. Cytidine deaminase activity as a function of aglycon ring size

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FNCN-200059765

Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FNCN-200059765

Inhibition of HhaI DNA (Cytosine-C5) methyltransferase by oligodeoxyribonucleotides containing 5-aza-2'-deoxycytidine: examination of the intertwined roles of co-factor, target, transition state structure and enzyme conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FNCN-200059765

Isolation, characterization, and properties of a labile hydrolysis product of the antitumor nucleoside, 5-azacytidine

21 January 2018

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https://api.crossref.org/works/10.1081%2FNCN-200059765

HhaI methyltransferase flips its target base out of the DNA helix

21 January 2018

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https://api.crossref.org/works/10.1081%2FNCN-200059765

Zebularine: A Novel DNA Methylation Inhibitor that Forms a Covalent Complex with DNA Methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FNCN-200059765

Potent inhibition of HhaI DNA methylase by the aglycon of 2-(1H)-pyrimidinone riboside (zebularine) at the GCGC recognition domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FNCN-200059765

Worms gang up on bacteria

21 January 2018

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https://api.crossref.org/works/10.1081%2FNCN-200059765

Inhibition of DNA methylation and reactivation of silenced genes by zebularine

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FNCN-200059765

Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FNCN-200059765

Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FNCN-200059765

21 January 2018

Identifiers

DOI

10.1081/NCN-200059765

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13 August 2017

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