Current issues in adeno-associated viral vector production (Q36288924)

13 August 2017

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title

Current issues in adeno-associated viral vector production (English)

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13 August 2017

Merten OW

1

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13 August 2017

Gény-Fiamma C

series ordinal

2

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13 August 2017

Douar AM

series ordinal

3

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13 August 2017

publication date

1 October 2005

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13 August 2017

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13 August 2017

volume

12 Suppl 1

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13 August 2017

page(s)

S51-61

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Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

13 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Clades of Adeno-associated viruses are widely disseminated in human tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Two novel adeno-associated viruses from cynomolgus monkey: pseudotyping characterization of capsid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Alternative polyadenylation of adeno-associated virus type 5 RNA within an internal intron is governed by the distance between the promoter and the intron and is inhibited by U1 small nuclear RNP binding to the intervening donor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Update on the prevalence of serum antibodies (IgG and IgM) to adeno-associated virus (AAV).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Site-specific integration by adeno-associated virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Adeno-associated virus vector for high-frequency integration, expression, and rescue of genes in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Vaccinia virus, herpes simplex virus, and carcinogens induce DNA amplification in a human cell line and support replication of a helpervirus dependent parvovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Human cytomegalovirus completely helps adeno-associated virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Scalable purification of adeno-associated virus type 2, 4, or 5 using ion-exchange chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Factors influencing recombinant adeno-associated virus production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Adeno-associated virus vectors can be efficiently produced without helper virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Titration of AAV-2 particles via a novel capsid ELISA: packaging of genomes can limit production of recombinant AAV-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

A helper virus-free packaging system for recombinant adeno-associated virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Novel tools for production and purification of recombinant adenoassociated virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

100-liter transient transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Cell lines for the production of recombinant adeno-associated virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Improving rAAV production and purification: towards the definition of a scaleable process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Rep/Cap gene amplification and high-yield production of AAV in an A549 cell line expressing Rep/Cap.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Characterization of adenovirus-induced inverted terminal repeat-independent amplification of integrated adeno-associated virus rep-cap sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Replication of rep-cap genes is essential for the high-efficiency production of recombinant AAV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

High-titer adeno-associated viral vectors from a Rep/Cap cell line and hybrid shuttle virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Production of recombinant adeno-associated virus vectors using a packaging cell line and a hybrid recombinant adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Selective Rep-Cap gene amplification as a mechanism for high-titer recombinant AAV production from stable cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Structure and transcription of human papillomavirus sequences in cervical carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Recombinant adeno-associated viral vector production using stable packaging and producer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Development and characterization of a cell line for large-scale, serum-free production of recombinant adeno-associated viral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Identification of a replication-defective herpes simplex virus for recombinant adeno-associated virus type 2 (rAAV2) particle assembly using stable producer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Protease-deleted adenovirus vectors and complementing cell lines: potential applications of single-round replication mutants for vaccination and gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Feasibility of generating adeno-associated virus packaging cell lines containing inducible adenovirus helper genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

A novel gene expression control system and its use in stable, high-titer 293 cell-based adeno-associated virus packaging cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 Rep and Cap.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Production of recombinant adeno-associated type 5 (rAAV5) vectors using recombinant herpes simplex viruses containing rep and cap.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Transfection-free and scalable recombinant AAV vector production using HSV/AAV hybrids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Baculovirus--insect cell interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Insect cell cultivation: growth and kinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Insect cell culture for industrial production of recombinant proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Parvovirus diagnostics and vaccine production in insect cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

A novel method using baculovirus-mediated gene transfer for production of recombinant adeno-associated virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Insect cells as a factory to produce adeno-associated virus type 2 vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Production of recombinant adeno-associated viral vectors using a baculovirus/insect cell suspension culture system: from shake flasks to a 20-L bioreactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

7 January 2021

Discrimination between different types of human adeno-associated viruses in clinical samples by PCR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

7 January 2021

Targeted integration of adeno-associated virus (AAV) into human chromosome 19

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

7 January 2021

Nucleotide sequence and organization of the adeno-associated virus 2 genome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

7 January 2021

The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

7 January 2021

Subcellular compartmentalization of adeno-associated virus type 2 assembly

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

7 January 2021

Role for highly regulated rep gene expression in adeno-associated virus vector production

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

7 January 2021

Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

7 January 2021

Packaging cells based on inducible gene amplification for the production of adeno-associated virus vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

7 January 2021

Construction of baculovirus recombinants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302615

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302615

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13 August 2017

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