Retroviral vector production in the National Gene Vector Laboratory at Indiana University (Q36288912)

13 August 2017

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title

Retroviral vector production in the National Gene Vector Laboratory at Indiana University (English)

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13 August 2017

Cornetta K

1

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13 August 2017

Matheson L

series ordinal

2

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13 August 2017

Ballas C

series ordinal

3

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13 August 2017

publication date

1 October 2005

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13 August 2017

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13 August 2017

volume

12 Suppl 1

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13 August 2017

page(s)

S28-35

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302613

13 August 2017

exact match

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cites work

Expression of introduced genetic sequences in hematopoietic cells following retroviral-mediated gene transfer

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Human gene therapy comes of age.

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The basic science of gene therapy

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Gene transfer into humans--immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Construction of a Helper Cell Line for Avian Reticuloendotheliosis Virus Cloning Vectors

21 January 2018

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Retrovirus packaging cells.

21 January 2018

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Rapid titer determination using quantitative real-time PCR.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Packaging cell line characteristics and optimizing retroviral vector titer: the National Gene Vector Laboratory experience

21 January 2018

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Improved methods of retroviral vector transduction and production for gene therapy

21 January 2018

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State-of-the-art of the production of retroviral vectors

21 January 2018

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Clinical retroviral vector production: step filtration using clinically approved filters improves titers

21 January 2018

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Safety aspects of gene therapy

21 January 2018

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Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer

21 January 2018

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Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

21 January 2018

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A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

21 January 2018

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 January 2018

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Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

21 January 2018

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Good news for gene therapy

21 January 2018

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Gene therapy insertional mutagenesis insights

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Analysis of retroviral packaging lines for generation of replication-competent virus

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells

21 January 2018

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Characterization of recombinant helper retroviruses from Moloney-based vectors in ecotropic and amphotropic packaging cell lines

21 January 2018

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Characterization of a replication-competent retrovirus resulting from recombination of packaging and vector sequences

21 January 2018

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Replication-defective chimeric helper proviruses and factors affecting generation of competent virus: expression of Moloney murine leukemia virus structural genes via the metallothionein promoter

21 January 2018

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Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges

21 January 2018

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Characterization of recombination events leading to the production of an ecotropic replication-competent retrovirus in a GP+envAM12-derived producer cell line

21 January 2018

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Evaluation of recommendations for replication-competent retrovirus testing associated with use of retroviral vectors

21 January 2018

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Normal DBA/2 mouse cells synthesize a glycoprotein which interferes with MCF virus infection

21 January 2018

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Infection of human cells with murine amphotropic replication-competent retroviruses

21 January 2018

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Improved detection of replication-competent retrovirus.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Applications of the polymerase chain reaction in retroviral-mediated gene transfer and the analysis of gene-marked human TIL cells

21 January 2018

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Evaluation of PCR and ELISA assays for screening clinical trial subjects for replication-competent retrovirus

21 January 2018

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Biosafety monitoring of patients receiving intracerebral injections of murine retroviral vector producer cells

21 January 2018

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Detection of ecotropic replication-competent retroviruses: comparison of s(+)/l(-) and marker rescue assays

21 January 2018

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High-efficiency gene transfer to primary monkey airway epithelial cells with retrovirus vectors using the gibbon ape leukemia virus receptor

21 January 2018

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High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes

21 January 2018

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Safety testing for replication-competent retrovirus associated with gibbon ape leukemia virus-pseudotyped retroviral vectors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

VSV-G pseudotyped lentiviral vector particles produced in human cells are inactivated by human serum

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Sustained multilineage gene persistence and expression in dogs transplanted with CD34(+) marrow cells transduced by RD114-pseudotype oncoretrovirus vectors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Packaging cell line DNA contamination of vector supernatants: implication for laboratory and clinical research

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Retroviral particles produced from a stable human-derived packaging cell line transduce target cells with very high efficiencies

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

A novel human amphotropic packaging cell line: high titer, complement resistance, and improved safety.

21 January 2018

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Generation of retroviral vector for clinical studies using transient transfection

21 January 2018

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A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

A stable system for the high-titer production of multiply attenuated lentiviral vectors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

A simple and efficient method for the concentration and purification of recombinant retrovirus for increased hepatocyte transduction in vivo

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Biochemical recovery and purification of gene therapy vectors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Concentration of biomaterials: virus concentration and viral protein isolation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

A safe packaging line for gene transfer: separating viral genes on two different plasmids

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

7 January 2021

Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

7 January 2021

Amphotropic murine leukemia retrovirus is not an acute pathogen for primates

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

7 January 2021

A novel murine retrovirus identified during testing for helper virus in human gene transfer trials

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

7 January 2021

Formation of infectious hybrid virions with gibbon ape leukemia virus and human T-cell leukemia virus retroviral envelope glycoproteins and the gag and pol proteins of Moloney murine leukemia virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

7 January 2021

High-titer packaging cells producing recombinant retroviruses resistant to human serum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302613

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302613

1 reference

13 August 2017

1 reference