Conformational substates in enzyme mechanism: the 120 K structure of alpha-lytic protease at 1.5 A resolution (Q36280516)

13 August 2017

Conformational substates in enzyme mechanism: the 120 K structure of alpha-lytic protease at 1.5 A resolution (English)

1 reference

13 August 2017

S D Rader

1

1 reference

PMCID

2143753

13 August 2017

D A Agard

series ordinal

2

1 reference

13 August 2017

1 July 1997

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13 August 2017

1 reference

13 August 2017

6

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13 August 2017

7

1 reference

13 August 2017

1375-1386

1 reference

IVE (Image Visualization Environment): a software platform for all three-dimensional microscopy applications

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Thermal diffuse X-ray scattering and its contribution to understanding protein dynamics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Direct observation of protein solvation and discrete disorder with experimental crystallographic phases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Conformational substates in a protein: structure and dynamics of metmyoglobin at 80 K.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

On the size of the active site in proteases. I. Papain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Refined structure of alpha-lytic protease at 1.7 A resolution. Analysis of hydrogen bonding and solvent structure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Serine protease mechanism: structure of an inhibitory complex of alpha-lytic protease and a tightly bound peptide boronic acid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Structural plasticity broadens the specificity of an engineered protease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Temperature dependence of the low frequency dynamics of myoglobin. Measurement of the vibrational frequency distribution by inelastic neutron scattering

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Structural basis for broad specificity in alpha-lytic protease mutants

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

1.59 A structure of trypsin at 120 K: comparison of low temperature and room temperature structures

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

The Energy Landscapes and Motions of Proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Temperature-dependent X-ray diffraction as a probe of protein structural dynamics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Areas, volumes, packing and protein structure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Molecular structure of the α-lytic protease from Myxobacter 495 at 2·8 Å resolution

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Variability of conformations at crystal contacts in BPTI represent true low-energy structures: correspondence among lattice packing and molecular dynamics structures

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

The influence of temperature on lysozyme crystals. Structure and dynamics of protein and water.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Functional linkage between the active site of alpha-lytic protease and distant regions of structure: scanning alanine mutagenesis of a surface loop affects activity and substrate specificity

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

The role of mobility in the substrate binding and catalytic machinery of enzymes.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Exploration of disorder in protein structures by X-ray restrained molecular dynamics

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143753

Structural heterogeneity in protein crystals

21 October 2018

1 reference

12 December 2020

Harmonicity and anharmonicity in protein dynamics: a normal mode analysis and principal component analysis

1 reference

12 December 2020

The nature of the bacteriolytic proteases of Sorangium sp

1 reference

12 December 2020

Looking into the energy landscape of myoglobin

1 reference

12 December 2020

Kinetic properties of the binding of alpha-lytic protease to peptide boronic acids

1 reference

12 December 2020

Thermal expansion of a protein

1 reference

12 December 2020

Liquid-like movements in crystalline insulin

1 reference

12 December 2020

Thermal expansion of hen egg-white lysozyme. Comparison of the 1.9 A resolution structures of the tetragonal form of the enzyme at 100 K and 298 K

1 reference

12 December 2020

Molecular dynamics studied by analysis of the X-ray diffuse scattering from lysozyme crystals

1 reference

12 December 2020

Study of protein dynamics by X-ray diffraction

1 reference

12 December 2020

Crystalline ribonuclease A loses function below the dynamical transition at 220 K

1 reference

12 December 2020

Identifiers

DOI

10.1002/PRO.5560060701

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

PMCID

2143753