How to Use a Chemotherapeutic Agent When Resistance to It Threatens the Patient (Q36275612)

13 August 2017

How to Use a Chemotherapeutic Agent When Resistance to It Threatens the Patient (English)

1 reference

13 August 2017

1 reference

1 reference

3

1 reference

13 August 2017

Elsa Hansen

1

1 reference

PMCID

5300106

13 August 2017

Robert J Woods

series ordinal

2

1 reference

PMCID

5300106

13 August 2017

language of work or name

English

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publication date

9 February 2017

1 reference

13 August 2017

1 reference

13 August 2017

15

1 reference

13 August 2017

e2001110

1 reference

13 August 2017

2

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Creative Commons Attribution 4.0 International

13 August 2017

start time

9 February 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer

30 September 2017

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Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?

30 September 2017

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Bacteriocin production augments niche competition by enterococci in the mammalian gastrointestinal tract

30 September 2017

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Clinical management of resistance evolution in a bacterial infection: A case study

30 September 2017

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Engineering Microbiomes to Improve Plant and Animal Health

30 September 2017

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A small-molecule antivirulence agent for treating Clostridium difficile infection

30 September 2017

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How competition governs whether moderate or aggressive treatment minimizes antibiotic resistance

30 September 2017

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How I treat high-risk myeloma

30 September 2017

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Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms

30 September 2017

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Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance

30 September 2017

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The fitness costs of antibiotic resistance mutations

30 September 2017

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Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer.

30 September 2017

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Is selection relevant in the evolutionary emergence of drug resistance?

30 September 2017

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Applying pharmacokinetic/pharmacodynamic principles in critically ill patients: optimizing efficacy and reducing resistance development

30 September 2017

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The value of monitoring to control evolving populations

30 September 2017

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Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.

30 September 2017

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Cancer evolution: mathematical models and computational inference

30 September 2017

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Exploring the collaboration between antibiotics and the immune response in the treatment of acute, self-limiting infections

30 September 2017

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Evolution of acquired resistance to anti-cancer therapy

30 September 2017

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Gallium-mediated siderophore quenching as an evolutionarily robust antibacterial treatment

30 September 2017

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Resource competition may lead to effective treatment of antibiotic resistant infections

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Life history trade-offs in cancer evolution

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Anthracyclines induce DNA damage response-mediated protection against severe sepsis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Aggressive chemotherapy and the selection of drug resistant pathogens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Fecal transplantation for recurrent Clostridium difficile infection in older adults: a review

30 September 2017

1 reference

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Evolutionary dynamics of cancer in response to targeted combination therapy

30 September 2017

1 reference

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A modeling framework for the evolution and spread of antibiotic resistance: literature review and model categorization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

When the most potent combination of antibiotics selects for the greatest bacterial load: the smile-frown transition

30 September 2017

1 reference

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Comparison of the respiratory microbiome in healthy nonsmokers and smokers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Evolutionary foundations for cancer biology

30 September 2017

1 reference

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Duodenal infusion of donor feces for recurrent Clostridium difficile

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Antiretroviral dynamics determines HIV evolution and predicts therapy outcome

30 September 2017

1 reference

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The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Evolutionary dynamics of carcinogenesis and why targeted therapy does not work.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

New drugs for the treatment of tuberculosis: needs, challenges, promise, and prospects for the future

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Clonal evolution in cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

"One-size-fits-all"? Optimizing treatment duration for bacterial infections

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Overlooking evolution: a systematic analysis of cancer relapse and therapeutic resistance research

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Tempo and mode of inhibitor-mutagen antiviral therapies: a multidisciplinary approach

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

The evolution of plasmid-carried antibiotic resistance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Population biological principles of drug-resistance evolution in infectious diseases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

The continuing crisis in antibiotic resistance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Early palliative care for patients with metastatic non-small-cell lung cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Engineered bacterial communication prevents Vibrio cholerae virulence in an infant mouse model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Optimal drug synergy in antimicrobial treatments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

A theoretical quantitative model for evolution of cancer chemotherapy resistance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Compensation of fitness costs and reversibility of antibiotic resistance mutations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Anti-virulence strategies to combat bacteria-mediated disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Antivirulence drugs to target bacterial secretion systems

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

The impact of different antibiotic regimens on the emergence of antimicrobial-resistant bacteria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Accelerated evolution of resistance in multidrug environments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Cancer cell metabolism: Warburg and beyond

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Antibiotic resistance--what's dosing got to do with it?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Acquired resistance to tyrosine kinase inhibitors during cancer therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

The rising impact of mathematical modelling in epidemiology: antibiotic resistance research as a case study.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Mutant selection window hypothesis updated.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Targeting multidrug resistance in cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Evolution of resistance to cancer therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Drug resistance in cancer: principles of emergence and prevention

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Ovarian cancer: strategies for overcoming resistance to chemotherapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Mutations in the ABL kinase domain pre-exist the onset of imatinib treatment.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Multidrug resistance in cancer: role of ATP-dependent transporters

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Quantification of intrinsic residual viral replication in treated HIV-infected patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

The ecology of genetically diverse infections

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Antibiotic resistance in the intensive care unit

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

High-dose chemotherapy and peripheral blood progenitor cell transplantation in the treatment of breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Studies of antibiotic resistance within the patient, hospitals and the community using simple mathematical models

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Concomitant combination therapy for HIV infection preferable over sequential therapy with 3TC and non-nucleoside reverse transcriptase inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

The Forty-Year-Old Mutation Theory of Lurla and Delbrück and Its Pertinence to Cancer Chemotherapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

A decade of combination chemotherapy of advanced Hodgkin's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

The crisis in antibiotic resistance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

A mathematical model of drug resistance: heterogeneous tumors.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Conflicting objectives in chemotherapy with drug resistance.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

An example of the effects of drug resistance on the optimal schedule for a single drug in cancer chemotherapy.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Evaluation of some mathematical models for tumor growth.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Antibiotic exposure and resistance in mixed bacterial populations.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

A mathematical model of cancer chemotherapy with an optimal selection of parameters.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Low-intensity combination chemotherapy maximizes host survival time for tumors containing drug-resistant cells

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Optimal control of tumor size used to maximize survival time when cells are resistant to chemotherapy

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Optimal chemical control of populations developing drug resistance

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Mathematical approaches to optimization of cancer chemotherapy

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

The path of least resistance: aggressive or moderate treatment?

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Limiting damage during infection: lessons from infection tolerance for novel therapeutics.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Cancer chemotherapy: a critical analysis of its 60 years of history.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Tumor growth instability and its implications for chemotherapy.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

A change of strategy in the war on cancer.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Exploring the role of the immune response in preventing antibiotic resistance

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

The evolution of two mutations during clonal expansion

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Minimizing long-term tumor burden: the logic for metronomic chemotherapeutic dosing and its antiangiogenic basis.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

The optimal scheduling of two drugs with simple resistance for a problem in cancer chemotherapy.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Chemotherapeutic treatments involving drug resistance and level of normal cells as a criterion of toxicity.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Drug kinetics and drug resistance in optimal chemotherapy.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5300106

Modelling chemotherapy resistance in palliation and failed cure

22 September 2018

1 reference

12 December 2020

BIOMEDICINE. Targeting copper to treat breast cancer

1 reference

12 December 2020

Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine

1 reference

12 December 2020

Arguments supporting the concept of non-cross-resistant combinations of chemotherapy

1 reference

12 December 2020

A dominated and resistant subpopulation causes regrowth after response to 1,3-bis(2-chloroethyl)-1-nitrosourea treatment of a heterogeneous small cell lung cancer xenograft in nude mice

1 reference

12 December 2020

Targeting virulence: can we make evolution-proof drugs?

1 reference

12 December 2020

10.1371/JOURNAL.PBIO.2001110

Identifiers

DOI

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

PMCID

5300106