CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-beta: evidence for TGF-beta but not IL-10-dependent direct S mu-->S alpha and sequential S mu-->S gamma, S gamma-->S alpha DNA recombination (Q36243258)

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English	CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-beta: evidence for TGF-beta but not IL-10-dependent direct S mu-->S alpha and sequential S mu-->S gamma, S gamma-->S alpha DNA recombination	scientific article

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scholarly article

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6 December 2019

CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-beta: evidence for TGF-beta but not IL-10-dependent direct S mu-->S alpha and sequential S mu-->S gamma, S gamma-->S alpha DNA recombination (English)

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6 December 2019

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H Zan

1

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6 December 2019

A Cerutti

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6 December 2019

P Dramitinos

3

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A Schaffer

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P Casali

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1 November 1998

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6 December 2019

Journal of Immunology

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6 December 2019

161

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6 December 2019

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6 December 2019

5217-5225

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6 December 2019

CD40 ligand and appropriate cytokines induce switching to IgG, IgA, and IgE and coordinated germinal center and plasmacytoid phenotypic differentiation in a human monoclonal IgM+IgD+ B cell line.

1 reference

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1 October 2017

Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis

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1 October 2017

Antibody class switching

1 reference

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1 October 2017

Vasoactive intestinal peptide induces S(alpha)/S(mu) switch circular DNA in human B cells

1 reference

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1 October 2017

Decreased type II/type I TGF-beta receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-beta1.

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1 October 2017

Interleukin-10 induces immunoglobulin G isotype switch recombination in human CD40-activated naive B lymphocytes

1 reference

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1 October 2017

Transforming growth factor beta 1 selectivity stimulates immunoglobulin G2b secretion by lipopolysaccharide-activated murine B cells

1 reference

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1 October 2017

Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3

1 reference

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1 October 2017

Structure of the VH and VL segments of monoreactive and polyreactive IgA autoantibodies to DNA in patients with systemic lupus erythematosus

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1 October 2017

Cytokine mRNA expression during an in vitro response of human B lymphocytes: kinetics of B cell tumor necrosis factor alpha, interleukin (IL)6, IL-10, and transforming growth factor beta 1 mRNAs

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1 October 2017

Regulation of antibody production and class switching by TGF-beta.

1 reference

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1 October 2017

Human neoplastic B cells express more than two isotypes of immunoglobulins without deletion of heavy-chain constant-region genes

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Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene

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Biased distribution of recombination sites within S regions upon immunoglobulin class switch recombination induced by transforming growth factor beta and lipopolysaccharide

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1 October 2017

Identification and analysis of a novel human surface CD5- B lymphocyte subset producing natural antibodies

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1 October 2017

Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes

1 reference

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1 October 2017

Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A.

1 reference

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1 October 2017

CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells.

1 reference

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29 June 2018

Lack of intraclonal diversification in Ig heavy and light chain V region genes expressed by CD5+IgM+ chronic lymphocytic leukemia B cells: a multiple time point analysis

1 reference

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29 June 2018

Human dendritic cells skew isotype switching of CD40-activated naive B cells towards IgA1 and IgA2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4631047

29 June 2018

The human I alpha 1 and I alpha 2 germline promoter elements: proximal positive and distal negative elements may regulate the tissue specific expression of C alpha 1 and C alpha 2 germline transcripts

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29 June 2018

Molecular analysis of IgA deficiency. Evidence for impaired switching to IgA.

1 reference

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29 June 2018

Induction of human IgE synthesis in B cells by mast cells and basophils

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29 June 2018

The human I alpha 1 region contains a TGF-beta 1 responsive enhancer and a putative recombination hotspot

1 reference

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29 June 2018

Ig isotype switching in B lymphocytes. The effect of T cell-derived interleukins, cytokines, cholera toxin, and antigen on isotype switch frequency of a cloned B cell lymphoma

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29 June 2018

Structure of TGF-β1-induced human immunoglobulin Cα1 and Cα2 germ-line transcripts

1 reference

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29 June 2018

TGF-beta 1 induces germ-line transcripts of both IgA subclasses in human B lymphocytes.

1 reference

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29 June 2018

Transforming growth factor-beta directs IgA switching in human B cells

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29 June 2018

Ig mu-epsilon isotype switch in IL-4-treated human B lymphoblastoid cells. Evidence for a sequential switch

1 reference

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29 June 2018

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22 September 2018

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22 September 2018

Differential regulation of C alpha 1 and C alpha 2 germ-line and mature mRNA transcripts in human peripheral blood B cells.

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22 September 2018

Generation of memory B cells and plasma cells in vitro.

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22 September 2018

Ligation of CD40 induces sterile transcripts of multiple Ig H chain isotypes in human B cells

1 reference

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22 September 2018

Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9820493

12 December 2020

based on heuristic

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Regulation of human B cell function by recombinant CD40 ligand and other TNF-related ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/9820493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common sequence motif near nonhomologous recombination breakpoints involving Ig sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/9820493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel in vitro model for high-rate IgA class switching

1 reference

https://pubmed.ncbi.nlm.nih.gov/9820493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta 1 is required for secretion of IgG of all subclasses by LPS-activated murine B cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9820493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional CD40 ligand expressed by human blood dendritic cells is up-regulated by CD40 ligation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9820493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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6 December 2019

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6 December 2019

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