Coordinated Regulation of PPARγ Expression and Activity through Control of Chromatin Structure in Adipogenesis and Obesity (Q36238874)

13 August 2017

Coordinated Regulation of PPARγ Expression and Activity through Control of Chromatin Structure in Adipogenesis and Obesity (English)

1 reference

13 August 2017

0 references

1 reference

Philippe Lefebvre

4

0 references

Bart Staels

object named as

Bart Staels

series ordinal

3

0 references

author name string

Jérôme Eeckhoute

series ordinal

1

1 reference

PMCID

3444001

13 August 2017

Frédérik Oger

series ordinal

2

1 reference

13 August 2017

6 September 2012

1 reference

13 August 2017

1 reference

13 August 2017

2012

1 reference

13 August 2017

164140

1 reference

Creative Commons Attribution 3.0 Unported

13 August 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes

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Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones.

1 October 2017

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Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity

1 October 2017

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Global mapping of cell type-specific open chromatin by FAIRE-seq reveals the regulatory role of the NFI family in adipocyte differentiation

1 October 2017

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Forming functional fat: a growing understanding of adipocyte differentiation

1 October 2017

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The complex transcription regulatory landscape of our genome: control in three dimensions

1 October 2017

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Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

1 October 2017

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MiR-637 maintains the balance between adipocytes and osteoblasts by directly targeting Osterix.

1 October 2017

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MicroRNA regulation in mammalian adipogenesis.

1 October 2017

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miRTar: an integrated system for identifying miRNA-target interactions in human

1 October 2017

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Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis

1 October 2017

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Adipose tissue remodeling and obesity

1 October 2017

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Epigenetic codes of PPARγ in metabolic disease

1 October 2017

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Determinants of nucleosome organization in primary human cells

1 October 2017

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Paused RNA polymerase II as a developmental checkpoint

1 October 2017

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Non-coding RNAs as regulators of gene expression and epigenetics.

1 October 2017

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Transducin-like enhancer protein 1 mediates estrogen receptor binding and transcriptional activity in breast cancer cells

1 October 2017

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Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones

1 October 2017

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Control of nuclear receptor activities in metabolism by post-translational modifications

1 October 2017

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TLE3 is a dual-function transcriptional coregulator of adipogenesis

1 October 2017

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Mapping and analysis of chromatin state dynamics in nine human cell types

1 October 2017

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Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis.

1 October 2017

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Enhancer function: new insights into the regulation of tissue-specific gene expression

1 October 2017

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Functional and mechanistic diversity of distal transcription enhancers

1 October 2017

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miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression

1 October 2017

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Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation

1 October 2017

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Endogenous ligands for nuclear receptors: digging deeper

1 October 2017

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Comparative epigenomic analysis of murine and human adipogenesis

1 October 2017

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Cell line models for differentiation: preadipocytes and adipocytes.

1 October 2017

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Propagation of adipogenic signals through an epigenomic transition state.

1 October 2017

1 reference

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Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPARgamma in obese mice and humans

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

An oestrogen-receptor-α-bound human chromatin interactome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

The relationship between the evolution of microRNA targets and the length of their UTRs

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Analysis of epigenetic alterations to chromatin during development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Many paths to one goal? The proteins that recognize methylated DNA in eukaryotes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

A role of miR-27 in the regulation of adipogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Characterization of function and regulation of miR-24-1 and miR-31.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Posttranslational modifications of PPAR-gamma: fine-tuning the metabolic master regulator

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

MicroRNAs: target recognition and regulatory functions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

The nuclear orphan receptor COUP-TFII plays an essential role in adipogenesis, glucose homeostasis, and energy metabolism

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Combinatorial patterns of histone acetylations and methylations in the human genome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Fat and beyond: the diverse biology of PPARgamma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

The Groucho/TLE/Grg family of transcriptional co-repressors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Role of Krüppel-like factor 15 (KLF15) in transcriptional regulation of adipogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Adipose tissue gene expression profiling reveals distinct molecular pathways that define visceral adiposity in offspring of maternal protein-restricted rats

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

A survey of genes differentially expressed in subcutaneous and visceral adipose tissue in men.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Selective disruption of PPARgamma 2 impairs the development of adipose tissue and insulin sensitivity.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Temporal recruitment of transcription factors and SWI/SNF chromatin-remodeling enzymes during adipogenic induction of the peroxisome proliferator-activated receptor gamma nuclear hormone receptor

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

PPAR gamma is required for placental, cardiac, and adipose tissue development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

The organization, promoter analysis, and expression of the human PPARgamma gene

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Integrative genomics identifies the corepressor SMRT as a gatekeeper of adipogenesis through the transcription factors C/EBPβ and KAISO.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

TNFα-induced up-regulation of miR-155 inhibits adipogenesis by down-regulating early adipogenic transcription factors

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Cell-specific determinants of peroxisome proliferator-activated receptor gamma function in adipocytes and macrophages

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Dimethylation of histone H3 at lysine 36 demarcates regulatory and nonregulatory chromatin genome-wide

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Defining specificity of transcription factor regulatory activities.

29 June 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F164140

Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F164140

Histone H3 modifications associated with differentiation and long-term culture of mesenchymal adipose stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F164140

Obesity short-circuits stemness gene network in human adipose multipotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F164140

Connecting threads: epigenetics and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F164140

Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444001

Rat PPARs: Quantitative Analysis in Adult Rat Tissues and Regulation in Fasting and Refeeding

22 September 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F164140

Expression of peroxisome proliferator-activated receptors in lean and obese Zucker rats

21 January 2018

1 reference

12 December 2020

Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor gamma (PPARgamma). Differential activity of PPARgamma1 and -2 isoforms and influence of insulin

1 reference

12 December 2020

MicroRNA 21 regulates the proliferation of human adipose tissue-derived mesenchymal stem cells and high-fat diet-induced obesity alters microRNA 21 expression in white adipose tissues

1 reference

12 December 2020

microRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/164140

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

PMCID

3444001