Genetic manipulation of 11beta-hydroxysteroid dehydrogenases in mice (Q36232568)

12 August 2017

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title

Genetic manipulation of 11beta-hydroxysteroid dehydrogenases in mice (English)

1 reference

12 August 2017

Janice M Paterson

1

1 reference

PubMed ID

16105819

12 August 2017

Jonathan R Seckl

series ordinal

2

1 reference

PubMed ID

16105819

12 August 2017

John J Mullins

series ordinal

3

1 reference

12 August 2017

1 September 2005

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American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

12 August 2017

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12 August 2017

289

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12 August 2017

3

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12 August 2017

R642-52

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Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice

12 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Cloning and tissue distribution of the human 11 beta-hydroxysteroid dehydrogenase type 2 enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Hexose-6-phosphate dehydrogenase determines the reaction direction of 11beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Proliferation and differentiation of osteoblasts and adipocytes in rat bone marrow stromal cell cultures: Effects of dexamethasone and calcitriol

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

11beta-hydroxysteroid dehydrogenase type 2 in mouse aorta: localization and influence on response to glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Molecular genetic analysis of glucocorticoid signaling during mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Ontogeny and sexual dimorphic expression of mouse type 2 11beta-hydroxysteroid dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Sensitivity of bone to glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Point mutations abolish 11 beta-hydroxysteroid dehydrogenase type II activity in three families with the congenital syndrome of apparent mineralocorticoid excess.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Hidden Markov model analysis of motifs in steroid dehydrogenases and their homologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Endothelial cell dysfunction in mice after transgenic knockout of type 2, but not type 1, 11beta-hydroxysteroid dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

11beta-hydroxysteroid dehydrogenase type 1: a new regulator of fetal lung maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Foetal lung maturation in 11beta-hydroxysteroid dehydrogenase type 1 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Mice deficient in 11beta-hydroxysteroid dehydrogenase type 1 lack bone marrow adipocytes, but maintain normal bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Overexpression of 11beta-hydroxysteroid dehydrogenase-1 in adipose tissue is associated with acquired obesity and features of insulin resistance: studies in young adult monozygotic twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

The possible roles of mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type 2 in cardiac fibrosis in the spontaneously hypertensive rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

The type I and type II 11beta-hydroxysteroid dehydrogenase enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Evidence for independent 11-oxidase and 11-reductase activities of 11 beta-hydroxysteroid dehydrogenase: enzyme latency, phase transitions, and lipid requirements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Alteration of cardiac and renal functions in transgenic mice overexpressing human mineralocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Molecular basis for hypertension in the "type II variant" of apparent mineralocorticoid excess

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Subcutaneous adipose 11 beta-hydroxysteroid dehydrogenase type 1 activity and messenger ribonucleic acid levels are associated with adiposity and insulinemia in Pima Indians and Caucasians

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

'Liver-type' 11 beta-hydroxysteroid dehydrogenase cDNA encodes reductase but not dehydrogenase activity in intact mammalian COS-7 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Nonalcoholic fatty liver disease: a feature of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Association of nonalcoholic fatty liver disease with insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

11 Beta-hydroxysteroid dehydrogenase type 1 from human liver: dimerization and enzyme cooperativity support its postulated role as glucocorticoid reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

A transgenic model of visceral obesity and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Glucocorticoids, hypothalamo-pituitary-adrenal (HPA) development, and life after birth

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Steroid disorders in children: congenital adrenal hyperplasia and apparent mineralocorticoid excess

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

The intracellular localization of the mineralocorticoid receptor is regulated by 11beta-hydroxysteroid dehydrogenase type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Congenital deficiency of 11beta-hydroxysteroid dehydrogenase (apparent mineralocorticoid excess syndrome): diagnostic value of urinary free cortisol and cortisone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Effect of dexamethasone withdrawal on osteoblastic differentiation of bone marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Tissue-specific dysregulation of cortisol metabolism in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Obesity, insulin resistance, and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Glucocorticoid osteoporosis--mechanisms and management

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Aldosterone-induced organ damage: plasma aldosterone level and inappropriate salt status

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Glucocorticoid programming of the fetus; adult phenotypes and molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

11beta-hydroxysteroid dehydrogenase type 1 as a modulator of glucocorticoid action: from metabolism to memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

11Beta-hydroxysteroid dehydrogenases: a novel control of glucocorticoid action in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Transgenic expression of 11beta-hydroxysteroid dehydrogenase type 2 in osteoblasts reveals an anabolic role for endogenous glucocorticoids in bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Ontogeny of glucocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type-1 gene expression identifies potential critical periods of glucocorticoid susceptibility during development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Differential expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 mRNA and glucocorticoid receptor protein during mouse embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Spatial and temporal patterns of expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 messenger RNA and glucocorticoid receptor protein in the murine placenta and uterus during late pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Aldosterone, through novel signaling proteins, is a fundamental molecular bridge between the genetic defect and the cardiac phenotype of hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

The role of corticosteriods in the regulation of vascular tone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

A genetic defect resulting in mild low-renin hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

Apparent mineralocorticoid excess in a Brazilian kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00017.2005

10.1152/AJPREGU.00017.2005

21 January 2018

Identifiers

DOI

1 reference

12 August 2017

1 reference

PubMed ID

16105819