A fail-safe mechanism for maintaining self-tolerance (Q36231679)

12 August 2017

A fail-safe mechanism for maintaining self-tolerance (English)

1 reference

12 August 2017

2

Matzinger P

1 reference

12 August 2017

S. Guerder

1

1 reference

PubMed ID

1386876

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1386876

21 September 2022

language of work or name

English

0 references

publication date

1 August 1992

1 reference

PMCID

2119333

full work available at URL

12 August 2017

https://europepmc.org/articles/PMC2119333

1 reference

PubMed ID

1386876

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1386876

https://europepmc.org/articles/PMC2119333?pdf=render

21 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

PubMed ID

1386876

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1386876

Journal of Experimental Medicine

21 September 2022

published in

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12 August 2017

176

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12 August 2017

2

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12 August 2017

553-564

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Helper activity is required for the in vivo generation of cytotoxic T lymphocytes

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Role of the H-2 complex in the induction of T cell tolerance to self minor histocompatibility antigens

1 October 2017

1 reference

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Concomitant induction of the cell surface expression of Ia determinants and accessory cell function by a murine macrophage tumor cell line

1 October 2017

1 reference

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Normal mammalian muscle differentiation and gene control of isocitrate dehydrogenase synthesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Monoclonal antibodies against human Ia antigens stimulate monocytes to secrete interleukin 1

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Low frequency of somatic mutation in beta-chain variable region genes of human T-cell receptors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Tolerance induced by thymic epithelial grafts in birds

1 October 2017

1 reference

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Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo

1 October 2017

1 reference

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Direct activation of CD8+ cytotoxic T lymphocytes by dendritic cells

1 October 2017

1 reference

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Rare peripheral T cells migrate to and persist in normal mouse thymus

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Interleukin 1 production during accessory cell-dependent mitogenesis of T lymphocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities

1 October 2017

1 reference

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In vivo induction of antigen-specific transplantation tolerance to Qa1a by exposure to alloantigen in the absence of T-cell help

1 October 2017

1 reference

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Reentry of T cells to the adult thymus is restricted to activated T cells

1 October 2017

1 reference

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Activation events during thymic selection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

A new analysis of allogeneic interactions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

H-2-nonrestricted cytotoxic responses to an antigen encoded telomeric to H-2D

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

A monoclonal antibody discriminating between subsets of T and B cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Thymic cytotoxic T lymphocytes are primed in vivo to minor histocompatibility antigens

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Genetics of the rat CT system: its apparent complexity is a consequence of cross-reactivity between the distinct MHC class I antigens RT1.C and RT1.A.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Induction of tolerance by monoclonal antibody therapy

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Induction of classical transplantation tolerance in the adult

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Masking of veto function in vivo by activated CD4+ T lymphocytes

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Activation versus tolerance: a decision made by T helper cells.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

The induction of skin graft tolerance in major histocompatibility complex-mismatched or primed recipients: primed T cells can be tolerized in the periphery with anti-CD4 and anti-CD8 antibodies

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Th1 and Th2 clones differ in their response to a tolerogenic signal

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Thymic requirement for clonal deletion during T cell development

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Regulation of Qa-1 expression and determinant modification by an H-2D-linked gene, Qdm.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Two roles for CD4 cells in the control of the generation of cytotoxic T lymphocytes

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Immune responses of thymusf/ymphocyte embryonic chimeras: studies on tolerance and major histocompatibility complex restriction inXenopus

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119333

Antigen presentation by keratinocytes induces tolerance in human T cells

5 December 2018

1 reference

12 December 2020

An immunological suppressor cell inactivating cytotoxic T-lymphocyte precursor cells recognizing it

1 reference

12 December 2020

Qa-1 restricted recognition of foreign antigen by a γδ T-cell hybridoma

1 reference

12 December 2020

Correlation of Qa-1 determinants defined by antisera and by cytotoxic T lymphocytes

1 reference

12 December 2020

Tolerance of class I histocompatibility antigens expressed extrathymically

1 reference

12 December 2020

Thymic cortical epithelial cells can present self-antigens in vivo

1 reference

12 December 2020

Induction of immune tolerance by administration of monoclonal antibody to L3T4

1 reference

12 December 2020

Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic β cells

1 reference

12 December 2020

Functional clonal deletion of class I-specific cytotoxic T lymphocytes by veto cells that express antigen

1 reference

12 December 2020

T-cell receptors generated via mutations are specific for various major histocompatibility antigens

1 reference

12 December 2020

Self tolerance is H–2-restricted

1 reference

12 December 2020

In vitro responses to the liver antigen F

1 reference

12 December 2020

Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant

1 reference

12 December 2020

A nondeletional mechanism of thymic self tolerance

1 reference

12 December 2020

Failure of T cell receptor V beta negative selection in an athymic environment

1 reference

12 December 2020

T cell immunity or tolerance as a consequence of self antigen presentation

1 reference

12 December 2020

Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells

1 reference

12 December 2020

Regulation of macrophage populations. I. Preferential induction of Ia-rich peritoneal exudates by immunologic stimuli

1 reference

12 December 2020

Reversal diabetes by islet transplantation: vulnerability of the established allograft

1 reference

12 December 2020

Biochemical identification of the Qa-1 alloantigen

1 reference

12 December 2020

Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand

1 reference

12 December 2020

Can B cells turn on virgin T cells?

1 reference

12 December 2020

Role of lymphokine-activated killer cells as mediators of veto and natural suppression

1 reference

12 December 2020

T cell tolerance by clonal elimination in the thymus

1 reference

12 December 2020

A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

1 reference

12 December 2020

A gene governing the female immune response to the male antigen in mice

1 reference

12 December 2020

Suppression of cell-mediated lymphocytotoxicity against minor histocompatibility antigens mediated by Lyt-1+Lyt−2+ T cells of stimulator-strain origin

1 reference

12 December 2020

Automated colorimetric assay for T cell cytotoxicity

1 reference

12 December 2020

Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.176.2.553

1 reference

12 August 2017

1 reference

12 August 2017

1 reference

PMCID

2119333