Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers (Q36229311)

12 August 2017

Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers (English)

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12 August 2017

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Guillermina Girardi

6

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author name string

Rashmi Sood

1

1 reference

12 August 2017

Mark Zogg

2

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12 August 2017

Randal J Westrick

3

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12 August 2017

Yi-He Guo

4

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12 August 2017

Edward J Kerschen

5

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12 August 2017

Jane E Salmon

7

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12 August 2017

Shaun R Coughlin

8

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12 August 2017

Hartmut Weiler

9

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12 August 2017

language of work or name

English

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publication date

16 April 2007

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Journal of Experimental Medicine

12 August 2017

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12 August 2017

204

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12 August 2017

5

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12 August 2017

1049-1056

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describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2118565/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Fetomaternal cross talk in the placental vascular bed: control of coagulation by trophoblast cells

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Extraembryonic expression of EPCR is essential for embryonic viability

1 October 2017

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Mice with a severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities

1 October 2017

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Evaluation of the association between hereditary thrombophilias and recurrent pregnancy loss: a meta-analysis

1 October 2017

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Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder

1 October 2017

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Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome

1 October 2017

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Thrombophilic disorders and fetal loss: a meta-analysis

1 October 2017

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Naturally occurring mutations in the thrombomodulin gene leading to impaired expression and function

1 October 2017

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Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome

1 October 2017

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Prevalence of a 23bp insertion in exon 3 of the endothelial cell protein C receptor gene in venous thrombophilia

1 October 2017

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A 23bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function

1 October 2017

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Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist

1 October 2017

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Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis

1 October 2017

1 reference

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Structural and functional characterization of the mouse von Willebrand factor receptor GPIb-IX with novel monoclonal antibodies

1 October 2017

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Safety of low-molecular-weight heparin in pregnancy: a systematic review.

1 October 2017

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A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state

1 October 2017

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Thrombomodulin gene variations and thromboembolic disease

1 October 2017

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Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice.

1 October 2017

1 reference

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Do placental lesions reflect thrombophilia state in women with adverse pregnancy outcome?

29 June 2018

1 reference

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Efficacy and safety of two doses of enoxaparin in women with thrombophilia and recurrent pregnancy loss: the LIVE-ENOX study

21 January 2018

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Thromboprophylaxis improves the live birth rate in women with consecutive recurrent miscarriages and hereditary thrombophilia

21 January 2018

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The long and winding road ... towards LMWH for pregnancy loss

21 January 2018

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Low molecular weight heparin for repeated pregnancy loss: is it based on solid evidence?

21 January 2018

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The thrombomodulin-protein C system is essential for the maintenance of pregnancy.

21 January 2018

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The association between adverse pregnancy outcomes and maternal factor V Leiden genotype: a meta-analysis.

21 January 2018

1 reference

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Tissue-restricted expression of thrombomodulin in the placenta rescues thrombomodulin-deficient mice from early lethality and reveals a secondary developmental block.

22 September 2018

1 reference

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Placental pathology in early onset pre-eclampsia and intra-uterine growth restriction in women with and without thrombophilia

22 September 2018

1 reference

12 December 2020

Lethal perinatal thrombosis in mice resulting from the interaction of tissue factor pathway inhibitor deficiency and factor V Leiden

1 reference

12 December 2020

Mice with a severe deficiency of the endothelial protein C receptor gene develop, survive, and reproduce normally, and do not present with enhanced arterial thrombosis after challenge

1 reference

12 December 2020

Mutations in promoter region of thrombomodulin and venous thromboembolic disease

1 reference

12 December 2020

The use of LMWH in pregnancies at risk: new evidence or perception?

1 reference

12 December 2020

Platelet-derived soluble factors induce human extravillous trophoblast migration and differentiation: platelets are a possible regulator of trophoblast infiltration into maternal spiral arteries

1 reference

12 December 2020

Factor V Leiden and prothrombin G20210A polymorphisms as risk factors for miscarriage during a first intended pregnancy: the matched case-control 'NOHA first' study

1 reference

12 December 2020

Spontaneous thrombosis in mice carrying the factor V Leiden mutation

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20062566

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

17438064

1 reference