Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2 (Q36223383)

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13 November 2019

title

Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2 (English)

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13 November 2019

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angiogenesis inhibitor

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7

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13 November 2019

author name string

P Lin

1

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13 November 2019

J A Buxton

2

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13 November 2019

A Acheson

3

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13 November 2019

C Radziejewski

4

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13 November 2019

P C Maisonpierre

5

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13 November 2019

G D Yancopoulos

6

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13 November 2019

L P Hale

8

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M W Dewhirst

9

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S E George

10

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13 November 2019

K G Peters

11

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13 November 2019

publication date

1 July 1998

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Proceedings of the National Academy of Sciences of the United States of America

13 November 2019

language of work or name

English

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published in

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volume

95

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issue

15

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13 November 2019

page(s)

8829-8834

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Expression of Tie2/Tek in breast tumour vasculature provides a new marker for evaluation of tumour angiogenesis

13 November 2019

cites work

1 reference

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Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor

1 October 2017

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Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth

1 October 2017

1 reference

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Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

1 October 2017

1 reference

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Improved adenoviral vectors: cautious optimism for gene therapy

1 October 2017

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Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

1 October 2017

1 reference

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Adenoviral gene transfer of nitric oxide synthase: high level expression in human vascular cells

1 October 2017

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Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor

1 October 2017

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Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells

1 October 2017

1 reference

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Gene therapy: adenovirus vectors.

1 October 2017

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Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

1 October 2017

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Expression of tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage

1 October 2017

1 reference

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Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

1 October 2017

1 reference

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Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma

1 October 2017

1 reference

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1 October 2017

1 reference

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The possible role of angiogenesis in the metastatic potential of human melanoma. Clinicopathological aspects

1 October 2017

1 reference

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Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

1 October 2017

1 reference

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The role of vascular permeability factor and basic fibroblast growth factor in tumor angiogenesis

1 October 2017

1 reference

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The implications of angiogenesis for the biology and therapy of cancer metastasis

1 October 2017

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Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma

1 October 2017

1 reference

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What Is the Evidence That Tumors Are Angiogenesis Dependent?

1 October 2017

1 reference

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Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

1 October 2017

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Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

29 June 2018

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A functional soluble extracellular region of the platelet-derived growth factor (PDGF) beta-receptor antagonizes PDGF-stimulated responses

29 June 2018

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29 June 2018

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Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma

29 June 2018

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Adeno-associated virus-mediated gene transfer into rat carotid arteries

29 June 2018

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Tie2 Expression and Phosphorylation in Angiogenic and Quiescent Adult Tissues

22 September 2018

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Gene therapy - promises, problems and prospects

22 September 2018

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22 September 2018

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22 September 2018

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The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors.

22 September 2018

1 reference

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Vascularization of the mouse embryo: A study of flk‐1, tek, tie, and vascular endothelial growth factor expression during development

22 September 2018

1 reference

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Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis.

22 September 2018

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Microvessel quantitation and prognosis in invasive breast carcinoma

22 September 2018

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12 December 2020

Relation of neovascularisation to metastasis of non-small-cell lung cancer

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12 December 2020

Abrogation of B16 melanoma metastases by long-term low-dose interleukin-6 therapy

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12 December 2020

Tumor angiogenesis is an independent prognostic indicator in primary breast carcinoma

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12 December 2020

Angiogenesis and breast cancer

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12 December 2020

Angiogenesis and risk of breast cancer in women with fibrocystic disease

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12 December 2020

Specificity of vascular endothelial cell growth factor receptor ligand binding domains

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12 December 2020

The Relationship of Angiogenesis to Biological Activity in Human Squamous Cell Carcinomas of the Head and Neck

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12 December 2020

Identifiers

DOI

10.1073/PNAS.95.15.8829

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9671764%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

0 references

1 reference

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13 November 2019

PubMed publication ID

9671764

1 reference