Transformation of NIH 3T3 cells with basic fibroblast growth factor or the hst/K-fgf oncogene causes downregulation of the fibroblast growth factor receptor: reversal of morphological transformation and restoration of receptor number by suramin. (Q36221812)

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English	Transformation of NIH 3T3 cells with basic fibroblast growth factor or the hst/K-fgf oncogene causes downregulation of the fibroblast growth factor receptor: reversal of morphological transformation and restoration of receptor number by suramin.	scientific article

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30 September 2019

Transformation of NIH 3T3 cells with basic fibroblast growth factor or the hst/K-fgf oncogene causes downregulation of the fibroblast growth factor receptor: reversal of morphological transformation and restoration of receptor number by suramin (English)

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30 September 2019

David Moscatelli

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30 September 2019

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1 November 1989

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30 September 2019

Journal of Cell Biology

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30 September 2019

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30 September 2019

2519-2527

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30 September 2019

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30 September 2019

Blockade of autocrine stimulation in simian sarcoma virus-transformed cells reverses down-regulation of platelet-derived growth factor receptors

1 reference

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Mr 25,000 heparin-binding protein from guinea pig brain is a high molecular weight form of basic fibroblast growth factor

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Processing, secretion, and biological properties of a novel growth factor of the fibroblast growth factor family with oncogenic potential

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Synthesis of membrane-bound colony-stimulating factor 1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes

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Evidence and characterization of the receptor to eye-derived growth factor I, the retinal form of basic fibroblast growth factor, on bovine epithelial lens cells

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Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation

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Genomic sequence of hst, a transforming gene encoding a protein homologous to fibroblast growth factors and the int-2-encoded protein

1 reference

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An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family

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cDNA sequence of human transforming gene hst and identification of the coding sequence required for transforming activity

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Metabolism of receptor-bound and matrix-bound basic fibroblast growth factor by bovine capillary endothelial cells

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Rapid turnover of the platelet-derived growth factor receptor in sis-transformed cells and reversal by suramin. Implications for the mechanism of autocrine transformation

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Expression of acidic fibroblast growth factor cDNA confers growth advantage and tumorigenesis to Swiss 3T3 cells

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Transformation of mouse BALB/c 3T3 cells with human basic fibroblast growth factor cDNA.

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Human basic fibroblast growth factor gene encodes four polypeptides: three initiate translation from non-AUG codons

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Recent developments in the cell biology of basic fibroblast growth factor

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1 October 2017

Structural characterization and biological functions of fibroblast growth factor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115849

1 October 2017

Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors

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29 June 2018

Expression in rat fibroblasts of a human transforming growth factor-alpha cDNA results in transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115849

29 June 2018

Expression of human basic fibroblast growth factor cDNA in baby hamster kidney-derived cells results in autonomous cell growth

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Basic fibroblast growth factor fused to a signal peptide transforms cells

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Bovine brain-derived growth factor. Purification and characterization of its interaction with responsive cells

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29 June 2018

Identification of the fibroblast growth factor receptor of Swiss 3T3 cells and mouse skeletal muscle myoblasts

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115849

29 June 2018

Identification of the fibroblast growth factor receptor in human vascular endothelial cells

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An amino-terminally extended and post-translationally modified form of a 25kD basic fibroblast growth factor

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1 reference

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1 reference

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Potential oncogene product related to growth factors

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Suramin inhibition of growth factor receptor binding and mitogenicity in AKR-2B cells

1 reference

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1 reference

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Comparative endocrinology-paracrinology-autocrinology of human adult large vessel endothelial and smooth muscle cells

1 reference

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Regulatory effects of cell density on the binding of transforming growth factor beta, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor

1 reference

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1 reference

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/2553749

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inferred from PubMed ID database lookup

Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/2553749

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Both normal and tumor cells produce basic fibroblast growth factor

1 reference

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Identifiers

10.1083/JCB.109.5.2519

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30 September 2019

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30 September 2019

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30 September 2019

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