Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production. (Q36219326)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production (English)

1 reference

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12 February 2020

1 reference

9

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12 February 2020

Teresa Lambe

2

1 reference

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12 February 2020

Fabienne Mackay

15

1 reference

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12 February 2020

Elissa K. Deenick

16

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12 February 2020

Stuart Tangye

17

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12 February 2020

Chris Goodnow

24

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12 February 2020

author name string

Katrina L Randall

1

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12 February 2020

Andy L Johnson

3

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12 February 2020

Bebhinn Treanor

4

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12 February 2020

Edyta Kucharska

5

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12 February 2020

Heather Domaschenz

6

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12 February 2020

Belinda Whittle

7

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12 February 2020

Lina E Tze

8

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12 February 2020

Tanya L Crockford

10

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12 February 2020

Tiphaine Bouriez-Jones

11

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12 February 2020

Duncan Alston

12

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12 February 2020

Jason G Cyster

13

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12 February 2020

Michael J Lenardo

14

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12 February 2020

Tyani D Chan

18

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12 February 2020

Tahra Camidge

19

1 reference

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12 February 2020

Robert Brink

20

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12 February 2020

Carola G Vinuesa

21

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12 February 2020

Facundo D Batista

22

1 reference

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12 February 2020

Richard J Cornall

23

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12 February 2020

language of work or name

English

0 references

publication date

8 November 2009

1 reference

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12 February 2020

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12 February 2020

volume

10

1 reference

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12 February 2020

page(s)

1283-1291

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12 February 2020

issue

12

1 reference

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Combined immunodeficiency associated with DOCK8 mutations

12 February 2020

cites work

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GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

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Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

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TACI is mutant in common variable immunodeficiency and IgA deficiency

1 October 2017

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Isolation and characterisation of DOCK8, a member of the DOCK180-related regulators of cell morphology

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Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation

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X-ray snapshots of the maturation of an antibody response to a protein antigen

1 October 2017

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B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells.

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Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency

1 October 2017

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A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

1 October 2017

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Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice

1 October 2017

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1 October 2017

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Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

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1 October 2017

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CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification

1 October 2017

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Opening a window on thymic positive selection: developmental changes in the influence of cosignaling by integrins and CD28 on selection events induced by TCR engagement

1 October 2017

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Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response

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1 October 2017

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22 September 2018

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22 September 2018

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FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses.

22 September 2018

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Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans.

22 September 2018

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CD19 regulates B cell maturation, proliferation, and positive selection in the FDC zone of murine splenic germinal centers.

22 September 2018

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Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

22 September 2018

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LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation.

22 September 2018

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Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis.

22 September 2018

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Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function

22 September 2018

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The physiologic role of CD19 cytoplasmic tyrosines

22 September 2018

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Integrin-mediated long-term B cell retention in the splenic marginal zone.

22 September 2018

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Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development.

22 September 2018

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Soluble antigen can cause enhanced apoptosis of germinal-centre B cells.

22 September 2018

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Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

22 September 2018

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Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

22 September 2018

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Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells.

22 September 2018

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Prolyl 4-hydroxylation regulates Argonaute 2 stability

22 September 2018

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Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation

21 January 2018

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Intercellular Adhesion Molecule-1-Dependent Stable Interactions between T Cells and Dendritic Cells Determine CD8+ T Cell Memory

21 January 2018

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CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand

21 January 2018

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12 December 2020

Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk

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12 December 2020

Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling

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12 December 2020

CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase

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12 December 2020

Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling

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12 December 2020

The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes

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12 December 2020

Identifiers

DOI

10.1038/NI.1820

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference