Molecular targets in spinal cord injury (Q36216362)

12 August 2017

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title

Molecular targets in spinal cord injury (English)

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12 August 2017

2

Ana Martin-Villalba

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12 August 2017

Stefan Klussmann

1

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12 August 2017

2 August 2005

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Journal of Molecular Medicine

12 August 2017

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12 August 2017

83

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12 August 2017

9

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12 August 2017

657-671

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https://scigraph.springernature.com/pub.10.1007/s00109-005-0663-3

12 August 2017

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cites work

Comparison of iNOS inhibition by antisense and pharmacological inhibitors after spinal cord injury

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Crossref

https://api.crossref.org/works/10.1007%2FS00109-005-0663-3

Induction of caspase-mediated cell death by matrix metalloproteinases in cerebral endothelial cells after hypoxia-reoxygenation

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS00109-005-0663-3

Recent advances in pathophysiology and treatment of spinal cord injury

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS00109-005-0663-3

Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair

21 January 2018

1 reference

12 December 2020

Effects of neutralizing antibodies to TNF-alpha on pain-related behavior and nerve regeneration in mice with chronic constriction injury

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12 December 2020

Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury.

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12 December 2020

Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat.

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12 December 2020

Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat

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12 December 2020

Pretreatment with Calpain Inhibitor CEP-4143 Inhibits Calpain I Activation and Cytoskeletal Degradation, Improves Neurological Function, and Enhances Axonal Survival After Traumatic Spinal Cord Injury

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12 December 2020

Analysis of the effects of cyclooxygenase (COX)-1 and COX-2 in spinal nociceptive transmission using indomethacin, a non-selective COX inhibitor, and NS-398, a COX-2 selective inhibitor.

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12 December 2020

Role of the bcl-2 gene after contusive spinal cord injury in mice.

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12 December 2020

Agmatine improves locomotor function and reduces tissue damage following spinal cord injury

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12 December 2020

Neuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system

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12 December 2020

The neuregulin, glial growth factor 2, diminishes autoimmune demyelination and enhances remyelination in a chronic relapsing model for multiple sclerosis

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12 December 2020

Key role for pregnenolone in combination therapy that promotes recovery after spinal cord injury

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12 December 2020

The neuroprotective pharmacology of methylprednisolone

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12 December 2020

Superoxide dismutase activity and the effects of NBQX and CPP on lipid peroxidation in experimental spinal cord injury

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12 December 2020

Apoptosis after traumatic human spinal cord injury

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12 December 2020

Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats

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12 December 2020

Effects of EPC-K1 on lipid peroxidation in experimental spinal cord injury

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12 December 2020

Suppression of p75NTR does not promote regeneration of injured spinal cord in mice.

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12 December 2020

Repair of demyelinated lesions by transplantation of purified 0-2A progenitor cells

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12 December 2020

Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells.

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12 December 2020

Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading

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12 December 2020

Cyclosporin-A inhibits lipid peroxidation after spinal cord injury in rats

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12 December 2020

Neuronal and glial apoptosis after traumatic spinal cord injury.

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12 December 2020

Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion.

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12 December 2020

Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth

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12 December 2020

Olfactory ensheathing cells (OECs) and the treatment of CNS injury: advantages and possible caveats.

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12 December 2020

Systemically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats

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12 December 2020

Apoptotic pathway and MAPKs differentially regulate chemotropic responses of retinal growth cones

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12 December 2020

Endothelial-leukocyte adhesion molecules

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12 December 2020

A novel effect of an opioid receptor antagonist, naloxone, on the production of reactive oxygen species by microglia: a study by electron paramagnetic resonance spectroscopy.

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12 December 2020

Rho kinase inhibition enhances axonal regeneration in the injured CNS.

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12 December 2020

Vaccination with dendritic cells pulsed with peptides of myelin basic protein promotes functional recovery from spinal cord injury

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12 December 2020

Effect of 4-aminopyridine and single-dose methylprednisolone on functional recovery after a chronic spinal cord injury

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12 December 2020

Calpain in the pathophysiology of spinal cord injury: neuroprotection with calpain inhibitors

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12 December 2020

CXCR3-dependent microglial recruitment is essential for dendrite loss after brain lesion.

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12 December 2020

Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice

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12 December 2020

Transplants and neurotrophic factors increase regeneration and recovery of function after spinal cord injury.

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12 December 2020

Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. Results of the second National Acute Spinal Cord Injury Study

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12 December 2020

The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion

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12 December 2020

Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury

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12 December 2020

Chemokine antagonist infusion attenuates cellular infiltration following spinal cord contusion injury in rat.

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12 December 2020

ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

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12 December 2020

Pleiotropic functions of erythropoietin

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12 December 2020

Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord I

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12 December 2020

Potent protective effects of melatonin on experimental spinal cord injury

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12 December 2020

Locomotor activity in spinal cord-injured persons

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12 December 2020

Role of cyclooxygenase 2 in acute spinal cord injury

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12 December 2020

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

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12 December 2020

Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors

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12 December 2020

Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury

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12 December 2020

Apoptosis of oligodendrocytes occurs for long distances away from the primary injury after compression trauma to rat spinal cord

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12 December 2020

P2X7 receptor inhibition improves recovery after spinal cord injury

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12 December 2020

Role of tumor necrosis factor-alpha in neuronal and glial apoptosis after spinal cord injury

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12 December 2020

Erythropoietin protects against brain ischemic injury by inhibition of nitric oxide formation

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12 December 2020

Purification of olfactory nerve ensheathing cells from the olfactory bulb.

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12 December 2020

Radial glia: multi-purpose cells for vertebrate brain development

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12 December 2020

Biochemistry and pharmacology of lipid antioxidants in acute brain and spinal cord injury

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12 December 2020

Overexpression of hyperactive integrin-linked kinase leads to increased cellular radiosensitivity.

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12 December 2020

The role of Fas-mediated apoptosis after traumatic spinal cord injury

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12 December 2020

The role of steroids in acute spinal cord injury: an evidence-based analysis

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12 December 2020

Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants.

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12 December 2020

Stem cell transplantation and other novel techniques for promoting recovery from spinal cord injury

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12 December 2020

P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp

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12 December 2020

The effects of topical L-arginine and Ng-nitro-L-arginine methyl ester after experimental acute spinal cord injury. A light and electron microscopic study

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12 December 2020

The Nogo signaling pathway for regeneration block

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12 December 2020

Regeneration beyond the glial scar

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12 December 2020

Enhanced Oligodendrocyte Survival after Spinal Cord Injury in Bax-Deficient Mice and Mice with Delayed Wallerian Degeneration

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12 December 2020

cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury

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12 December 2020

Derivatives of erythropoietin that are tissue protective but not erythropoietic

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12 December 2020

Lack of enhanced spinal regeneration in Nogo-deficient mice

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12 December 2020

Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1

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12 December 2020

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

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12 December 2020

Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia

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12 December 2020

Remyelination by transplanted olfactory ensheathing cells.

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12 December 2020

Production of neurotrophins by activated T cells: implications for neuroprotective autoimmunity

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12 December 2020

Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury.

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12 December 2020

IL-1 receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury.

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12 December 2020

Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX

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12 December 2020

Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein

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12 December 2020

Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord

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12 December 2020

Involvement of an intercellular adhesion molecule 1-dependent pathway in the pathogenesis of secondary changes after spinal cord injury in rats

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12 December 2020

Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells.

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12 December 2020

Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury.

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12 December 2020

Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades

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12 December 2020

Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma

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12 December 2020

Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury.

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12 December 2020

Improved recovery after spinal cord injury in neuronal nitric oxide synthase-deficient mice but not in TNF-alpha-deficient mice.

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12 December 2020

Axonal regrowth after spinal cord transection in adult zebrafish

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12 December 2020

Prior Exposure to Neurotrophins Blocks Inhibition of Axonal Regeneration by MAG and Myelin via a cAMP-Dependent Mechanism

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12 December 2020

Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter.

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12 December 2020

Targeting recovery: priorities of the spinal cord-injured population

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12 December 2020

Methylprednisolone and interleukin-10 reduce gray matter damage in the contused Fischer rat thoracic spinal cord but do not improve functional outcome

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12 December 2020

Adenosine A2A analogue improves neurologic outcome after spinal cord trauma in the rabbit

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12 December 2020

Human monoclonal antibodies reactive to oligodendrocytes promote remyelination in a model of multiple sclerosis

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12 December 2020

Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys

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12 December 2020

Inhibitor of neurite outgrowth in humans

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12 December 2020

Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke

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12 December 2020

Efficacy of a new neuroprotective agent, gacyclidine, in a model of rat spinal cord injury

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12 December 2020

Regenerating the damaged central nervous system

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12 December 2020

Lipid peroxides in the free radical pathophysiology of brain diseases.

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12 December 2020

Schwann cells induce sprouting in motor and sensory axons in the adult rat spinal cord

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12 December 2020

Effects of the sodium channel blocker tetrodotoxin on acute white matter pathology after experimental contusive spinal cord injury.

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12 December 2020

Neuroprotection by encephalomyelitis: rescue of mechanically injured neurons and neurotrophin production by CNS-infiltrating T and natural killer cells.

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12 December 2020

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

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12 December 2020

In vivo neuroprotection of injured CNS neurons by a single injection of a DNA plasmid encoding the Bcl-2 gene

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12 December 2020

The effects of chronic alpha-tocopherol administration on lipid peroxidation in an experimental model of acute spinal cord injury

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12 December 2020

Inhibition of bladder activity by 5-hydroxytryptamine1 serotonin receptor agonists in cats with chronic spinal cord injury.

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12 December 2020

From bench to clinic with apoptosis-based therapeutic agents

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12 December 2020

Neural stem cells and cell death

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12 December 2020

Early expression and cellular localization of proinflammatory cytokines interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in human traumatic spinal cord injury.

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12 December 2020

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

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12 December 2020

Effects of lecithinized superoxide dismutase on rat spinal cord injury

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12 December 2020

The phosphodiesterase inhibitor rolipram delivered after a spinal cord lesion promotes axonal regeneration and functional recovery

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12 December 2020

Spinal axon regeneration induced by elevation of cyclic AMP.

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12 December 2020

Vaccination with a Nogo-A-derived peptide after incomplete spinal-cord injury promotes recovery via a T-cell-mediated neuroprotective response: comparison with other myelin antigens

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12 December 2020

A role for cAMP in regeneration of the adult mammalian CNS.

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12 December 2020

Transplantation of rat Schwann cells grown in tissue culture into the mouse spinal cord

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12 December 2020

Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries

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12 December 2020

Cyclic AMP-induced repair of zebrafish spinal circuits

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12 December 2020

Reduction of pathological and behavioral deficits following spinal cord contusion injury with the selective cyclooxygenase-2 inhibitor NS-398.

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12 December 2020

Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up. Results of the third National Acute Spinal Cord Injury randomized controlled trial.

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12 December 2020

Spinal cord injury: promising interventions and realistic goals

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12 December 2020

Preclinical trial of 4-aminopyridine in patients with chronic spinal cord injury

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12 December 2020

Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury

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12 December 2020

Pain following spinal cord injury: pathophysiology and central mechanisms

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12 December 2020

Peripherally delivered glutamic acid decarboxylase gene therapy for spinal cord injury pain

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12 December 2020

Stress, Glucocorticoids, and Damage to the Nervous System: The Current State of Confusion.

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12 December 2020

The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho.

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12 December 2020

Axon regeneration in young adult mice lacking Nogo-A/B.

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12 December 2020

Tumor necrosis factor receptor deletion reduces nuclear factor-kappaB activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury

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12 December 2020

Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus.

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12 December 2020

Therapeutic strategies targeting caspase inhibition following spinal cord injury in rats

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12 December 2020

Injury in the spinal cord may produce cell death in the brain.

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12 December 2020

A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

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12 December 2020

Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth, and myelination

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12 December 2020

Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats.

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12 December 2020

Nogo-66 receptor antagonist peptide promotes axonal regeneration

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12 December 2020

Efficacy of methylprednisolone therapy for the injured rat spinal cord

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12 December 2020

Estrogen as a neuroprotective agent in the treatment of spinal cord injury

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12 December 2020

Inactivation of Rho signaling pathway promotes CNS axon regeneration

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12 December 2020

The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats

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12 December 2020

Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury

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12 December 2020

Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells.

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12 December 2020

Erythropoietin therapy for acute stroke is both safe and beneficial

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12 December 2020

Chondroitinase ABC promotes functional recovery after spinal cord injury

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12 December 2020

Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology

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12 December 2020

Integrins: versatility, modulation, and signaling in cell adhesion

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12 December 2020

Primary cortical motor neurons undergo apoptosis after axotomizing spinal cord injury

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12 December 2020

Rho signaling pathway targeted to promote spinal cord repair.

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12 December 2020

Effects of Naloxone and Nalmefene in Rat Spinal Cord Injury Induced by the Ventral Compression Technique

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12 December 2020

Evaluation of the neuroprotective effects of sodium channel blockers after spinal cord injury: improved behavioral and neuroanatomical recovery with riluzole.

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12 December 2020

Overexpression of SOD1 protects vulnerable motor neurons after spinal cord injury by attenuating mitochondrial cytochrome c release.

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12 December 2020

Apoptosis and expression of Bcl-2 after compression trauma to rat spinal cord

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12 December 2020

Olfactory ensheathing cells - another miracle cure for spinal cord injury?

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12 December 2020

Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis

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12 December 2020

Progesterone is neuroprotective after acute experimental spinal cord trauma in rats

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12 December 2020

Metalloproteinases in biology and pathology of the nervous system.

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12 December 2020

An Adverse Role for Matrix Metalloproteinase 12 after Spinal Cord Injury in Mice

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12 December 2020

Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo.

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12 December 2020

Induction and its spread of apoptosis in rat spinal cord after mechanical trauma.

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12 December 2020

Role of neutrophils in spinal cord injury in the rat

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12 December 2020

Improved recovery after spinal cord trauma in ICAM-1 and P-selectin knockout mice

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12 December 2020

Apoptosis in the nervous system

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12 December 2020

Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function.

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12 December 2020

Mechanical allodynia following contusion injury of the rat spinal cord is associated with loss of GABAergic inhibition in the dorsal horn

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12 December 2020

Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration

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12 December 2020

Gacyclidine (Beaufour-Ipsen).

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12 December 2020

Nogo and axon regeneration

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12 December 2020

Identification of a neural stem cell in the adult mammalian central nervous system

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12 December 2020

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

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12 December 2020

BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia

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12 December 2020

Matrix metalloproteinases limit functional recovery after spinal cord injury by modulation of early vascular events.

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12 December 2020

Steroids and spinal cord injury: revisiting the NASCIS 2 and NASCIS 3 trials

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12 December 2020

10.1007/S00109-005-0663-3

Identifiers

DOI

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12 August 2017

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PubMed ID

16075258