P2X receptors: targets for novel analgesics? (Q36215233)

12 August 2017

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title

P2X receptors: targets for novel analgesics? (English)

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12 August 2017

Charles Kennedy

1

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12 August 2017

1 August 2005

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12 August 2017

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12 August 2017

11

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12 August 2017

4

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12 August 2017

345-356

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The expression of P2X3 purinoreceptors in sensory neurons: effects of axotomy and glial-derived neurotrophic factor.

12 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Heteromultimeric P2X(1/2) receptors show a novel sensitivity to extracellular pH

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Purine-mediated signalling in pain and visceral perception

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Is there a basis for distinguishing two types of P2-purinoceptor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Purinergic receptors: their role in nociception and primary afferent neurotransmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Sense and specificity: a molecular identity for nociceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

A P2X purinoceptor expressed by a subset of sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Cell damage excites nociceptors through release of cytosolic ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

siRNA relieves chronic neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Contribution of calcium ions to P2X channel responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Selective activation of nociceptors by P2X receptor agonists in normal and inflamed rat skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Functional characterization of the P2X(4) receptor orthologues

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Functional regulation of P2X6 receptors by N-linked glycosylation: identification of a novel alpha beta-methylene ATP-sensitive phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Alteration of dorsal root ganglion P2X3 receptor expression and function following spinal nerve ligation in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Crossing the pain barrier: P2 receptors as targets for novel analgesics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

How should P2X purinoceptors be classified pharmacologically?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Painful connection for ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Ultrastructural localization of P2X3 receptors in rat sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

The induction of pain: an integrative review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Distinct roles of P2X receptors in modulating glutamate release at different primary sensory synapses in rat spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Molecular physiology of P2X receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Immunocytochemical localization of P2X3 purinoceptors in sensory neurons in naive rats and following neuropathic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Analgesic effects of intrathecal administration of P2Y nucleotide receptor agonists UTP and UDP in normal and neuropathic pain model rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Inflammatory mediators potentiate ATP-gated channels through the P2X(3) subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Distribution of P2X1, P2X2, and P2X3 receptor subunits in rat primary afferents: relation to population markers and specific cell types.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Pharmacological properties of P2X3-receptors present in neurones of the rat dorsal root ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Characterization of a P2X-purinoceptor in cultured neurones of the rat dorsal root ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Tackling pain at the source: new ideas about nociceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

TNP-ATP-resistant P2X ionic current on the central terminals and somata of rat primary sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Differential regulation of P2X(3) mRNA expression by peripheral nerve injury in intact and injured neurons in the rat sensory ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Cell type-specific ATP-activated responses in rat dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

P2X3 receptor localizes into lipid rafts in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Molecular properties of ATP-gated P2X receptor ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Distinct neurochemical mechanisms are activated following administration of different P2X receptor agonists into the hindpaw of a rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

Neuronal plasticity: increasing the gain in pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858404274063

21 January 2018

Identifiers

DOI

10.1177/1073858404274063

1 reference

12 August 2017

1 reference

PubMed ID

16061521