Randomized phase II trial designs with biomarkers (Q36212448)

12 August 2017

Randomized phase II trial designs with biomarkers (English)

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12 August 2017

phase II clinical trial

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1

Boris Freidlin

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12 August 2017

Lisa M McShane

2

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12 August 2017

Mei-Yin C Polley

series ordinal

3

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12 August 2017

Edward L Korn

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4

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12 August 2017

language of work or name

English

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publication date

6 August 2012

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Journal of Clinical Oncology

12 August 2017

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12 August 2017

30

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12 August 2017

26

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12 August 2017

3304-3309

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Design issues in randomized phase II/III trials

12 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434989

Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434989

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

1 October 2017

1 reference

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Everolimus for advanced pancreatic neuroendocrine tumors.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434989

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434989

Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434989

Randomized clinical trials with biomarkers: design issues

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434989

Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma

1 October 2017

1 reference

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Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434989

Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial

1 October 2017

1 reference

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Monitoring for lack of benefit: a critical component of a randomized clinical trial

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434989

K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

1 October 2017

1 reference

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Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial

1 October 2017

1 reference

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MGMT gene silencing and benefit from temozolomide in glioblastoma

1 October 2017

1 reference

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Impact of exploratory biomarkers on the treatment effect of bevacizumab in metastatic breast cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434989

Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial.

29 June 2018

1 reference

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22 September 2018

Identifiers

DOI

10.1200/JCO.2012.43.3946

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12 August 2017

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12 August 2017

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