Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development (Q36207412)

12 August 2017

Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development (English)

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12 August 2017

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1

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4 June 2020

Adam P Cribbs

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4 June 2020

Claudia Monaco

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4 June 2020

author name string

Nagore Astola

2

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4 June 2020

Michael E Goddard

4

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4 June 2020

Inhye Park

5

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4 June 2020

Patricia Green

6

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4 June 2020

Alun H Davies

7

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4 June 2020

Richard O Williams

8

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4 June 2020

Marc Feldmann

9

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4 June 2020

language of work or name

English

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publication date

5 October 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

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4 June 2020

volume

112

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4 June 2020

issue

42

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4 June 2020

page(s)

13033-13038

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Inhibition of indoleamine 2,3-dioxygenase promotes vascular inflammation and increases atherosclerosis in Apoe-/- mice.

4 June 2020

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1 October 2017

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1 October 2017

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1 October 2017

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Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease

1 October 2017

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Kynurenine is an endothelium-derived relaxing factor produced during inflammation

1 October 2017

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Assessment of unstable atherosclerosis in mice

1 October 2017

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Multiple risk factors for cardiovascular disease and diabetes mellitus

1 October 2017

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Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines

1 October 2017

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Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite

1 October 2017

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IDO expression by dendritic cells: tolerance and tryptophan catabolism

1 October 2017

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Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial

1 October 2017

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Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis

1 October 2017

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Of mice and not men: differences between mouse and human immunology

1 October 2017

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Immune activation and degradation of tryptophan in coronary heart disease

1 October 2017

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Endogenous kynurenines as targets for drug discovery and development

1 October 2017

1 reference

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Results of Prevention of REStenosis with Tranilast and its Outcomes (PRESTO) trial

1 October 2017

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Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase.

1 October 2017

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Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites

1 October 2017

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Atherosclerotic plaque rupture--pathologic basis of plaque stability and instability

1 October 2017

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Pharmacological properties of N-(3',4'-dimethoxycinnamoyl) anthranilic acid (N-5'), a new anti-atopic agent

1 October 2017

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Lipopolysaccharide induction of indoleamine 2,3-dioxygenase is mediated dominantly by an IFN-gamma-independent mechanism

1 October 2017

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Indoleamine 2,3-Dioxygenase Fine-Tunes Immune Homeostasis in Atherosclerosis and Colitis through Repression of Interleukin-10 Production.

29 June 2018

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Activation of indoleamine 2,3-dioxygenase-induced tryptophan degradation in advanced atherosclerotic plaques: Tampere vascular study

22 September 2018

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Indoleamine 2,3-dioxygenase activity associates with cardiovascular risk factors: the Health 2000 study

22 September 2018

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22 September 2018

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Indoleamine 2,3-dioxygenase enzyme activity correlates with risk factors for atherosclerosis: the Cardiovascular Risk in Young Finns Study.

22 September 2018

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The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor pravastatin reduces disease activity and inflammation in dextran-sulfate induced colitis

22 September 2018

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A novel anti-inflammatory role for simvastatin in inflammatory arthritis

22 September 2018

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The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

22 September 2018

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The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells

22 September 2018

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The anti-allergic drug, N-(3',4'-dimethoxycinnamonyl) anthranilic acid, exhibits potent anti-inflammatory and analgesic properties in arthritis

21 October 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1517820112

The tryptophan metabolite 3-hydroxyanthranilic acid lowers plasma lipids and decreases atherosclerosis in hypercholesterolaemic mice

21 January 2018

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12 December 2020

B regulatory cells are increased in hypercholesterolaemic mice and protect from lesion development via IL-10

1 reference

12 December 2020

Induction of indoleamine dioxygenase by interferon in mice: a study with different recombinant interferons and various cytokines

1 reference

12 December 2020

Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1517820112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26438837%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

0 references

1 reference

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4 June 2020

1 reference

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