Clinically relevant subsets identified by gene expression patterns support a revised ontogenic model of Wilms tumor: a Children's Oncology Group Study (Q36200428)

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English	Clinically relevant subsets identified by gene expression patterns support a revised ontogenic model of Wilms tumor: a Children's Oncology Group Study	scientific article

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scholarly article

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Europe PubMed Central

12 August 2017

Clinically relevant subsets identified by gene expression patterns support a revised ontogenic model of Wilms tumor: a Children's Oncology Group Study (English)

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Europe PubMed Central

12 August 2017

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based on heuristic

inferred from title

6

object named as

Paul E Grundy

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Europe PubMed Central

12 August 2017

2

object named as

Vicki Huff

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Europe PubMed Central

12 August 2017

E. Cristy Ruteshouser

4

object named as

E Cristy Ruteshouser

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Europe PubMed Central

12 August 2017

5

object named as

Jeffrey S Dome

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Europe PubMed Central

12 August 2017

author name string

Samantha Gadd

1

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Europe PubMed Central

12 August 2017

Chiang-Ching Huang

3

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Europe PubMed Central

12 August 2017

Norman Breslow

7

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Europe PubMed Central

12 August 2017

Lawrence Jennings

8

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Europe PubMed Central

12 August 2017

Daniel M Green

9

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Europe PubMed Central

12 August 2017

J Bruce Beckwith

10

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12 August 2017

Elizabeth J Perlman

11

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12 August 2017

publication date

1 August 2012

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Europe PubMed Central

12 August 2017

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Europe PubMed Central

12 August 2017

14

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12 August 2017

742-756

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Europe PubMed Central

12 August 2017

8

1 reference

Europe PubMed Central

12 August 2017

WT1 in disease: shifting the epithelial-mesenchymal balance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

WT1 mutation and 11P15 loss of heterozygosity predict relapse in very low-risk wilms tumors treated with surgery alone: a children's oncology group study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Rhabdoid tumor: gene expression clues to pathogenesis and potential therapeutic targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Subfractionation of differentiating human embryonic stem cell populations allows the isolation of a mesodermal population enriched for intermediate mesoderm and putative renal progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Expression of AKR1C3 in renal cell carcinoma, papillary urothelial carcinoma, and Wilms' tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Subsets of very low risk Wilms tumor show distinctive gene expression, histologic, and clinical features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Predicting relapse in favorable histology Wilms tumor using gene expression analysis: a report from the Renal Tumor Committee of the Children's Oncology Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Atlas of gene expression in the developing kidney at microanatomic resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Functional inactivation of the WTX gene is not a frequent event in Wilms' tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Wilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

beta-catenin/TCF/Lef controls a differentiation-associated transcriptional program in renal epithelial progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Canonical WNT signaling during kidney development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

An X chromosome gene, WTX, is commonly inactivated in Wilms tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Target genes of the WNT/beta-catenin pathway in Wilms tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Classification of malignant pediatric renal tumors by gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Clear cell sarcoma of the kidney: up-regulation of neural markers with activation of the sonic hedgehog and Akt pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Loss of heterozygosity for chromosomes 1p and 16q is an adverse prognostic factor in favorable-histology Wilms tumor: a report from the National Wilms Tumor Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Expression profiling and functional analysis of wnt signaling mechanisms in mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

A catalogue of gene expression in the developing kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

WT1 proteins: functions in growth and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Treatment with nephrectomy only for small, stage I/favorable histology Wilms' tumor: a report from the National Wilms' Tumor Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Frequent association of beta-catenin and WT1 mutations in Wilms tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Confirmation of FWT1 as a Wilms' tumour susceptibility gene and phenotypic characteristics of Wilms' tumour attributable to FWT1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Cluster analysis and display of genome-wide expression patterns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Wilms tumor genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Correlation of germ-line mutations and two-hit inactivation of the WT1 gene with Wilms tumors of stromal-predominant histology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

WT-1 is required for early kidney development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Fine structure analysis of the WT1 gene in sporadic Wilms tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Repression of the transforming growth factor-beta 1 gene by the Wilms' tumor suppressor WT1 gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

WT1 exon 1 deletion/insertion mutations in Wilms tumor patients, associated with di- and trinucleotide repeats and deletion hotspot consensus sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Nonrandom loss of maternal chromosome 11 alleles in Wilms tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Genetic linkage of Beckwith-Wiedemann syndrome to 11p15.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms' tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

1 October 2017

Different CTNNB1 mutations as molecular genetic proof for the independent origin of four Wilms tumours in a patient with a novel germ line WT1 mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

2 July 2018

Sequential WT1 and CTNNB1 mutations and alterations of beta-catenin localisation in intralobar nephrogenic rests and associated Wilms tumours: two case studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

2 July 2018

Disruption of insulin-like growth factor 2 imprinting in Beckwith-Wiedemann syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

2 July 2018

Insulin-like growth factor II messenger ribonucleic acid expression in Wilms tumor, nephrogenic rest, and kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

2 July 2018

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

2 July 2018

WNT/beta-catenin pathway activation in Wilms tumors: a unifying mechanism with multiple entries?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

22 September 2018

Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

22 September 2018

Myogenesis in Wilms' tumors is associated with mutations of the WT1 gene and activation of Bcl-2 and the Wnt signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

22 September 2018

Epigenetic differences between Wilms' tumours in white and east-Asian children.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

22 September 2018

Relaxation of imprinted genes in human cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

22 September 2018

Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms' tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

21 October 2018

Infrequent mutation of theWT1 gene in 77 Wilms' tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431181

5 December 2018

Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/22952427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Duplication of paternal IGF2 or loss of maternal IGF2 imprinting occurs in half of Wilms tumors with various structural WT1 abnormalities

1 reference

https://pubmed.ncbi.nlm.nih.gov/22952427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Canonical WNT signalling determines lineage specificity in Wilms tumour

1 reference

https://pubmed.ncbi.nlm.nih.gov/22952427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mediators of receptor tyrosine kinase activation in infantile fibrosarcoma: a Children's Oncology Group study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22952427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of Imprinting of Insulin-Like Growth Factor-II (IGF2) Gene in Distinguishing Specific Biologic Subtypes of Wilms Tumor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22952427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour

1 reference

https://pubmed.ncbi.nlm.nih.gov/22952427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic mosaicism in normal tissues of Wilms' tumour patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22952427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGF2 is parentally imprinted during human embryogenesis and in the Beckwith-Wiedemann syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22952427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

1 reference

https://pubmed.ncbi.nlm.nih.gov/22952427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of WT1 function leads to ectopic myogenesis in Wilms' tumour

1 reference

https://pubmed.ncbi.nlm.nih.gov/22952427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage of familial Wilms' tumor predisposition to chromosome 19 and a two-locus model for the etiology of familial tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22952427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1593/NEO.12714

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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