Novel Lys63-linked ubiquitination of IKKβ induces STAT3 signaling (Q36189276)

12 August 2017

Novel Lys63-linked ubiquitination of IKKβ induces STAT3 signaling (English)

1 reference

12 August 2017

protein ubiquitination

1 reference

Leandro H Gallo

1

1 reference

12 August 2017

April N Meyer

2

1 reference

12 August 2017

Khatereh Motamedchaboki

3

1 reference

12 August 2017

Katelyn N Nelson

4

1 reference

12 August 2017

Martin Haas

5

1 reference

12 August 2017

Daniel J Donoghue

6

1 reference

12 August 2017

1 January 2014

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12 August 2017

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12 August 2017

13

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12 August 2017

24

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12 August 2017

3964-3976

1 reference

Creative Commons Attribution-NonCommercial 3.0 Unported

12 August 2017

start time

15 December 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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1 October 2017

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1 October 2017

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1 October 2017

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Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A.

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Inflammation meets cancer, with NF-κB as the matchmaker

1 October 2017

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1 October 2017

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1 October 2017

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The receptor tyrosine kinase FGFR4 negatively regulates NF-kappaB signaling

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Activation of NF-kappaB signaling by inhibitor of NF-kappaB kinase beta increases aggressiveness of ovarian cancer

1 October 2017

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Signaling to NF-kappaB: regulation by ubiquitination

1 October 2017

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STATs in cancer inflammation and immunity: a leading role for STAT3

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Ro52-mediated monoubiquitination of IKK{beta} down-regulates NF-{kappa}B signalling

1 October 2017

1 reference

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Ubiquitylation in innate and adaptive immunity.

1 October 2017

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Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Nonproteolytic functions of ubiquitin in cell signaling

1 October 2017

1 reference

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Nordihydroguaiaretic acid inhibits an activated fibroblast growth factor receptor 3 mutant and blocks downstream signaling in multiple myeloma cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

The genomic landscapes of human breast and colorectal cancers

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Multiple myeloma: lusting for NF-kappaB.

1 October 2017

1 reference

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Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

1 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

1 October 2017

1 reference

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The consensus coding sequences of human breast and colorectal cancers

1 October 2017

1 reference

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Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Site-specific monoubiquitination of IkappaB kinase IKKbeta regulates its phosphorylation and persistent activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

The role of IL-6 and STAT3 in inflammation and cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

IKK-beta links inflammation to obesity-induced insulin resistance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

A model for random sampling and estimation of relative protein abundance in shotgun proteomics

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Molecular mechanisms of novel therapeutic approaches for multiple myeloma

1 October 2017

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

1 October 2017

1 reference

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NF-kappa B regulation by I kappa B kinase-2 in rheumatoid arthritis synoviocytes

1 October 2017

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1 October 2017

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Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4615003

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 October 2017

1 reference

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A novel skeletal dysplasia with developmental delay and acanthosis nigricans is caused by a Lys650Met mutation in the fibroblast growth factor receptor 3 gene

1 October 2017

1 reference

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 October 2017

1 reference

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Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II

1 October 2017

1 reference

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Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma.

1 October 2017

1 reference

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Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2F15384101.2014.988026

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.

21 January 2018

1 reference

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Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2F15384101.2014.988026

Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25486864

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25486864

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/15384101.2014.988026

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

25486864

1 reference