Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities (Q36183732)

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English	Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities	scientific article

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities (English)

1 reference

Europe PubMed Central

12 August 2017

Gennady Yegutkin

1

object named as

Gennady G Yegutkin

1 reference

Europe PubMed Central

12 August 2017

4

object named as

Sirpa Jalkanen

1 reference

Europe PubMed Central

12 August 2017

author name string

Bé Wieringa

2

1 reference

Europe PubMed Central

12 August 2017

Simon C Robson

3

1 reference

Europe PubMed Central

12 August 2017

language of work or name

0 references

publication date

25 May 2012

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

26

1 reference

Europe PubMed Central

12 August 2017

3875-3883

1 reference

Europe PubMed Central

12 August 2017

9

1 reference

Europe PubMed Central

12 August 2017

Transgenic swine: expression of human CD39 protects against myocardial injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

The GDA1_CD39 superfamily: NTPDases with diverse functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Hypoxia and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

SP1-dependent induction of CD39 facilitates hepatic ischemic preconditioning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Central role of Sp1-regulated CD39 in hypoxia/ischemia protection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Secretion of adenylate kinase 1 is required for extracellular ATP synthesis in C2C12 myotubes

1 reference

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1 October 2017

The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance

1 reference

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1 October 2017

P2 receptors in cardiovascular regulation and disease

1 reference

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1 October 2017

Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

1 reference

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Regulation of platelet functions by P2 receptors

1 reference

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1 October 2017

Dynamics of nucleotide metabolism as a supporter of life phenomena

1 reference

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1 October 2017

Effects of SolCD39, a novel inhibitor of Platelet Aggregation, on Platelet Deposition and Aggregation after PTCA in a Porcine Model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Ectonucleotidases of CD39 Family Modulate Vascular Inflammation and Thrombosis in Transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Rat pancreas secretes particulate ecto-nucleotidase CD39

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Metabolic control of excessive extracellular nucleotide accumulation by CD39/ecto-nucleotidase-1: implications for ischemic vascular diseases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Elucidation of the thromboregulatory role of CD39/ectoapyrase in the ischemic brain

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phosphotransfer reactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Adenylate kinase 1 gene deletion disrupts muscle energetic economy despite metabolic rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

wt p53 dependent expression of a membrane-associated isoform of adenylate kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Nucleoside monophosphate kinases: structure, mechanism, and substrate specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Receptors for purines and pyrimidines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Inhibition of platelet function by recombinant soluble ecto-ADPase/CD39.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Loss of ATP diphosphohydrolase activity with endothelial cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Inhibition of ecto-ATPase by PPADS, suramin and reactive blue in endothelial cells, C6 glioma cells and RAW 264.7 macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Identification and characterization of CD39/vascular ATP diphosphohydrolase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto-ATPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

The adenylate kinase of human plasma, erythrocytes and platelets in relation to the degradation of adenosine diphosphate in plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

The clinical biochemistry of 5'-nucleotidase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

1 October 2017

Specificity of the ecto-ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

2 July 2018

Neuronal release of soluble nucleotidases and their role in neurotransmitter inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

2 July 2018

Detection and determination of adenosine diphosphate and related substances in plasma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

2 July 2018

Metabolism of adenine nucleotides in human blood

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

2 July 2018

Impaired ATP-induced coronary blood flow and diminished aortic NTPDase activity precede lesion formation in apolipoprotein E-deficient mice.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

23 September 2018

Two structurally distinct and spatially compartmentalized adenylate kinases are expressed from the AK1 gene in mouse brain

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

23 September 2018

Soluble purine-converting enzymes circulate in human blood and regulate extracellular ATP level via counteracting pyrophosphatase and phosphotransfer reactions

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

23 September 2018

Secreted and cell-associated adenylate kinase and nucleoside diphosphokinase contribute to extracellular nucleotide metabolism on human airway surfaces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

23 September 2018

Inhibitory effects of some purinergic agents on ecto-ATPase activity and pattern of stepwise ATP hydrolysis in rat liver plasma membranes.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425827

23 September 2018

Effect of shear stress on the release of soluble ecto-enzymes ATPase and 5'-nucleotidase along with endogenous ATP from vascular endothelial cells

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23 September 2018

Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation.

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23 September 2018

Polyoxometalates—a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors

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21 October 2018

Structural elements and limited proteolysis of CD39 influence ATP diphosphohydrolase activity

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12 December 2020

based on heuristic

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https://pubmed.ncbi.nlm.nih.gov/22637533

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ATP-consuming and ATP-generating Enzymes Secreted by Pancreas

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https://pubmed.ncbi.nlm.nih.gov/22637533

12 December 2020

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https://pubmed.ncbi.nlm.nih.gov/22637533

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inferred from PubMed ID database lookup

Generation of inorganic pyrophosphate from extracellular adenosine triphosphate by human serum and plasma

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https://pubmed.ncbi.nlm.nih.gov/22637533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Breakdown of adenine and hypoxanthine nucleotides and nucleosides in human plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22637533

12 December 2020

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Intravascular ADP and soluble nucleotidases contribute to acute prothrombotic state during vigorous exercise in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22637533

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Identifiers

10.1096/FJ.12-205658

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Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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