A NUP98-HOXD13 fusion gene impairs differentiation of B and T lymphocytes and leads to expansion of thymocytes with partial TCRB gene rearrangement. (Q36175294)

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English	A NUP98-HOXD13 fusion gene impairs differentiation of B and T lymphocytes and leads to expansion of thymocytes with partial TCRB gene rearrangement.	scientific article

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10 February 2020

A NUP98-HOXD13 fusion gene impairs differentiation of B and T lymphocytes and leads to expansion of thymocytes with partial TCRB gene rearrangement (English)

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10 February 2020

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Christopher I Slape

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10 February 2020

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Peter D Aplan

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10 February 2020

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Chul Won Choi

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10 February 2020

Yang Jo Chung

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19 October 2009

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10 February 2020

Journal of Immunology

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10 February 2020

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10 February 2020

6227-6235

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10 February 2020

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10 February 2020

Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell

1 reference

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The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia

1 reference

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NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.

1 reference

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Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia

1 reference

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A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors

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Thymic emigration: conveyor belts or lucky dips?

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1 October 2017

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

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1 October 2017

Immunologic Abnormalities in Myelodysplastic Syndromes

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Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes.

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HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription factor.

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scid Thymocytes with TCRbeta gene rearrangements are targets for the oncogenic effect of SCL and LMO1 transgenes.

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23 September 2018

NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia.

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Somatic recombination in a murine T-cell receptor gene

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23 September 2018

Flt3 ligand induces the outgrowth of Mac-1+B220+ mouse bone marrow progenitor cells restricted to macrophage differentiation that coexpress early B cell-associated genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19841179

12 December 2020

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Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19841179

12 December 2020

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Engraftment of distinct clonal MDS-derived hematopoietic precursors in NOD/SCID-beta2-microglobulin-deficient mice after intramedullary transplantation of hematopoietic and stromal cells

1 reference

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inferred from PubMed ID database lookup

Clonal analysis of myelodysplastic syndrome: monosomy 7 is expressed in the myeloid lineage, but not in the lymphoid lineage as detected by fluorescent in situ hybridization

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Rescue of T cell-specific V(D)J recombination in SCID mice by DNA-damaging agents

1 reference

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Fluorescence in situ hybridization of progenitor cells obtained by fluorescence-activated cell sorting for the detection of cells affected by chromosome abnormality trisomy 8 in patients with myelodysplastic syndromes

1 reference

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inferred from PubMed ID database lookup

A B220+ CD117+ CD19- hematopoietic progenitor with potent lymphoid and myeloid developmental potential

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients

1 reference

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inferred from PubMed ID database lookup

Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level

1 reference

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inferred from PubMed ID database lookup

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10.4049/JIMMUNOL.0901121

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Europe PubMed Central

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10 February 2020

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24 November 2022

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19841179%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

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10 February 2020

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