Fibroblast growth factor 23 (Q3616234)

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mammalian protein found in Homo sapiens

FGF23
phosphatonin
fibroblast growth factor 23
Tumor-derived hypophosphatemia-inducing factor
tumor-derived hypophosphatemia inducing factor
FGF23 protein, human

Language	Label	Description	Also known as
English	Fibroblast growth factor 23	mammalian protein found in Homo sapiens	FGF23 phosphatonin fibroblast growth factor 23 Tumor-derived hypophosphatemia-inducing factor tumor-derived hypophosphatemia inducing factor FGF23 protein, human

Statements

1 reference

13 November 2019

UniProt protein ID

fibroblast growth factor 23

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9GZV9

Cytokine IL1/FGF

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9GZV9

fibroblast growth factor 2

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Protein FGF23 PDB 2p39.png
833 × 639; 229 KB

0 references

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

fibroblast growth factor receptor binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

type 1 fibroblast growth factor receptor binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

protein tyrosine kinase activity

determination method

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9GZV9&geneProductId=UniProtKB:Q9GZV9

determination method

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

determination method

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9GZV9&geneProductId=UniProtKB:Q9GZV9

determination method

1-phosphatidylinositol-3-kinase activity

determination method

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9GZV9&geneProductId=UniProtKB:Q9GZV9

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

endoplasmic reticulum lumen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

biological process

cell differentiation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

negative regulation of bone mineralization

determination method

1 reference

8 April 2019

Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

cellular response to interleukin-6

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

vitamin D metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

regulation of bone mineralization

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

phosphate ion homeostasis

determination method

1 reference

8 April 2019

Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

cellular phosphate ion homeostasis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

response to magnesium ion

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

regulation of phosphate transport

determination method

1 reference

8 April 2019

FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

cellular response to vitamin D

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

negative regulation of osteoblast differentiation

determination method

1 reference

8 April 2019

Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

cellular response to leptin stimulus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

response to sodium phosphate

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

positive regulation of ERK1 and ERK2 cascade

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

positive regulation of vitamin D 24-hydroxylase activity

determination method

1 reference

8 April 2019

FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

phosphate-containing compound metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

vitamin D catabolic process

determination method

1 reference

8 April 2019

FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

cellular response to parathyroid hormone stimulus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

phosphatidylinositol phosphate biosynthetic process

determination method

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9GZV9&geneProductId=UniProtKB:Q9GZV9

determination method

peptidyl-tyrosine phosphorylation

determination method

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9GZV9&geneProductId=UniProtKB:Q9GZV9

determination method

phosphatidylinositol-3-phosphate biosynthetic process

determination method

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9GZV9&geneProductId=UniProtKB:Q9GZV9

determination method

post-translational protein modification

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

regulation of signaling receptor activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

positive regulation of protein kinase B signaling

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZV9

determination method

Gene Atlas image

PBB GE FGF23 221166 at fs.png
732 × 530; 12 KB

0 references

Identifiers

MeSH descriptor ID

subject named as

FGF23 protein, human

0 references

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000237837

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000237837

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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