Developmental pathway of CD4+CD8- medullary thymocytes during mouse ontogeny and its defect in Aire-/- mice (Q36156870)

12 August 2017

Developmental pathway of CD4+CD8- medullary thymocytes during mouse ontogeny and its defect in Aire-/- mice (English)

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12 August 2017

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Juan Li

1

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12 August 2017

Yan Li

2

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12 August 2017

Jin-Yan Yao

3

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12 August 2017

Rong Jin

4

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12 August 2017

Ming-Zhao Zhu

5

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12 August 2017

Xiao-Ping Qian

6

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12 August 2017

Jun Zhang

7

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12 August 2017

Yang-Xin Fu

8

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12 August 2017

Li Wu

9

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12 August 2017

Yu Zhang

10

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12 August 2017

Wei-Feng Chen

11

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12 August 2017

language of work or name

English

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publication date

5 November 2007

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Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

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12 August 2017

104

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12 August 2017

46

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12 August 2017

18175-18180

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NF-kappaB2 is required for the establishment of central tolerance through an Aire-dependent pathway

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

A survival guide to early T cell development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Journey through the thymus: stromal guides for T-cell development and selection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Developmental regulation of Foxp3 expression during ontogeny.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Molecular genetics of T cell development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Dependence of self-tolerance on TRAF6-directed development of thymic stroma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Lymphotoxin pathway directs thymic Aire expression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Aire regulates negative selection of organ-specific T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Projection of an immunological self shadow within the thymus by the aire protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Heterogeneity within medullary-type TCRalphabeta(+)CD3(+)CD4(-)CD8(+) thymocytes in normal mouse thymus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Effect of murine thymic epithelial cell line (MTEC1) on the functional expression of CD4(+)CD8(-) thymocyte subgroups

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Expression of relB is required for the development of thymic medulla and dendritic cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Thymic emigration: conveyor belts or lucky dips?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

The majority of postselection CD4+ single-positive thymocytes requires the thymus to produce long-lived, functional T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

CD4+ and CD8+ T cells acquire specific lymphokine secretion potentials during thymic maturation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

The majority of CD4+8- thymocytes are functionally immature

2 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

Multiple types of cytokines constitutively produced by an established murine thymic epithelial cell line

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner.

2 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0708884104

RelB reduces thymocyte apoptosis and regulates terminal thymocyte maturation.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0708884104

The cellular mechanism of Aire control of T cell tolerance.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0708884104

CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0708884104

Systematic mutagenesis of the functional domains of AIRE reveals their role in intracellular targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0708884104

Differentiation to T helper cells in the thymus. Gradual acquisition of T helper cell function by CD3+CD4+ cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084316

T-cell apoptosis detected in situ during positive and negative selection in the thymus

23 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0708884104

The thymus and negative selection

21 January 2018

1 reference

12 December 2020

Disorganization and restoration of thymic medullary epithelial cells in T cell receptor-negative scid mice: evidence that receptor-bearing lymphocytes influence maturation of the thymic microenvironment

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12 December 2020

Thymic cortical epithelium is sufficient for the development of mature T cells in relB-deficient mice

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12 December 2020

Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses

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12 December 2020

Recent thymic emigrants are distinct from most medullary thymocytes

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12 December 2020

Phenotypic identification of the subgroups of murine T-cell receptor alphabeta+ CD4+ CD8- thymocytes and its implication in the late stage of thymocyte development

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12 December 2020

Maturation of medullary thymic epithelium requires thymocytes expressing fully assembled CD3-TCR complexes

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12 December 2020

MTS-32 monoclonal antibody defines CD4+8- thymocyte subsets that differ in their maturation level, lymphokine secretion, and selection patterns

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12 December 2020

Production, selection, and maturation of thymocytes with high surface density of TCR

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12 December 2020

RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0708884104

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12 August 2017

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12 August 2017

PubMed publication ID

17984055

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