Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response. (Q36155852)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19728861%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response (English)

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6 February 2020

0 references

1 reference

4

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6 February 2020

3

Danyelle M Townsend

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6 February 2020

author name string

Stefka D Spassieva

series ordinal

1

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6 February 2020

Thomas D Mullen

series ordinal

2

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6 February 2020

language of work or name

English

0 references

publication date

11 November 2009

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6 February 2020

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6 February 2020

volume

424

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6 February 2020

page(s)

273-283

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6 February 2020

issue

2

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Senescence and cell death pathways and their role in cancer therapeutic outcome.

6 February 2020

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Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice

2 October 2017

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Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy

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Ceramide starves cells to death by downregulating nutrient transporter proteins

2 October 2017

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Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation

2 October 2017

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Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate

2 October 2017

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IRE1 signaling affects cell fate during the unfolded protein response

2 October 2017

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Unconventional splicing of XBP-1 mRNA in the unfolded protein response

2 October 2017

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(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1

2 October 2017

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Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas

2 October 2017

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Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival.

2 October 2017

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Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response

2 October 2017

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Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy

2 October 2017

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Autophagy is activated for cell survival after endoplasmic reticulum stress

2 October 2017

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2 October 2017

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Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity

2 October 2017

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Endoplasmic reticulum stress triggers autophagy

2 October 2017

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Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

2 October 2017

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When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesis

2 October 2017

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2 October 2017

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Mammalian Lass6 and its related family members regulate synthesis of specific ceramides

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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BcR-induced apoptosis involves differential regulation of C16 and C24-ceramide formation and sphingolipid-dependent activation of the proteasome

2 October 2017

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2 October 2017

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Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells

2 October 2017

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Regulation of de novo sphingolipid biosynthesis and the toxic consequences of its disruption

2 October 2017

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Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line

2 October 2017

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A ubiquitin-like system mediates protein lipidation

2 October 2017

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Autophagy as a regulated pathway of cellular degradation

2 October 2017

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

2 October 2017

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Developmental cell death: morphological diversity and multiple mechanisms

2 October 2017

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Lipid trafficking defects increase Beclin-1 and activate autophagy in Niemann-Pick type C disease

2 October 2017

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Molecular associations and surface-active properties of short- and long-N-acyl chain ceramides

2 July 2018

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Crossref

https://api.crossref.org/works/10.1042%2FBJ20090699

Lipid phase perturbations and the unfolded protein response

21 January 2018

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Crossref

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Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19728861

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of harvesting methods, growth conditions and growth phase on diacylglycerol levels in cultured human adherent cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19728861

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20090699

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19728861%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19728861%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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