Molecular pathology of non-small-cell lung cancer (Q36155104)

12 August 2017

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title

Molecular pathology of non-small-cell lung cancer (English)

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12 August 2017

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2

Postmus PE

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12 August 2017

Breuer RH

1

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PubMed ID

15942304

12 August 2017

Smit EF

series ordinal

3

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12 August 2017

1 May 2005

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12 August 2017

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12 August 2017

72

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12 August 2017

313-330

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12 August 2017

3

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The new World Health Organization classification of lung tumours

12 August 2017

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The changing epidemiology of lung cancer in Europe

21 January 2018

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Smoking, DNA repair capacity and risk of nonsmall cell lung cancer

21 January 2018

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Cigarette smoking and lung cancer: chemical mechanisms and approaches to prevention.

21 January 2018

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Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma

21 January 2018

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The ninth Gordon Hamilton-Fairley memorial lecture. Hereditary cancers: clues to mechanisms of carcinogenesis

21 January 2018

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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

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Distribution of p53 and K-ras mutations in human lung cancer tissues

21 January 2018

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The TP53 gene, tobacco exposure, and lung cancer

21 January 2018

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Suprabasal p53 immunostaining in premalignant endobronchial lesions in combination with histology is associated with bronchial cancer.

21 January 2018

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

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Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis

21 January 2018

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Alterations of expression of Rb, p16(INK4A) and cyclin D1 in non-small cell lung carcinoma and their clinical significance.

21 January 2018

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In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis

21 January 2018

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Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours

21 January 2018

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The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

21 January 2018

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The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression

21 January 2018

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Prognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small-cell lung cancer

21 January 2018

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Cyclin D1 overexpression in bronchial epithelia of patients with lung cancer is associated with smoking and predicts survival.

21 January 2018

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The FHIT gene 3p14.2 is abnormal in lung cancer.

21 January 2018

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Protein expression and functional analysis of the FHIT gene in human tumor cells

21 January 2018

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Replacement of Fhit in cancer cells suppresses tumorigenicity

21 January 2018

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The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1

21 January 2018

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Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours.

21 January 2018

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Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression

21 January 2018

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Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

21 January 2018

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Multiplicity generates diversity in the retinoic acid signalling pathways

21 January 2018

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RARbeta2 specificity in mediating RA inhibition of growth of lung cancer-derived cells

21 January 2018

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Suppression of retinoic acid receptor beta in non-small-cell lung cancer in vivo: implications for lung cancer development

21 January 2018

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Expression of Retinoid Receptor Genes and Proteins in Non-Small-Cell Lung Cancer

21 January 2018

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Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease

21 January 2018

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Neuropilin is a semaphorin III receptor

21 January 2018

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Expression of VEGF, semaphorin SEMA3F, and their common receptors neuropilins NP1 and NP2 in preinvasive bronchial lesions, lung tumours, and cell lines

21 January 2018

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Semaphorin SEMA3F localization in malignant human lung and cell lines: A suggested role in cell adhesion and cell migration

21 January 2018

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Regulation of the invasion suppressor function of the cadherin/catenin complex

21 January 2018

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Reduced expression of alpha-catenin, beta-catenin, and gamma-catenin is associated with high cell proliferative activity and poor differentiation in non-small cell lung cancer

21 January 2018

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TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer

21 January 2018

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The tumor suppressor protein TSLC1 is involved in cell-cell adhesion

21 January 2018

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Expression of the TSLC1 adhesion molecule in pulmonary epithelium and its down-regulation in pulmonary adenocarcinoma other than bronchioloalveolar carcinoma

21 January 2018

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Promoter methylation of the TSLC1 gene in advanced lung tumors and various cancer cell lines

21 January 2018

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Clinical implication and prognostic significance of the tumor suppressor TSLC1 gene detected in adenocarcinoma of the lung

21 January 2018

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

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Pten is essential for embryonic development and tumour suppression

21 January 2018

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

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Mutation analysis of the PTEN/MMAC1 gene in lung cancer

21 January 2018

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Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancers.

21 January 2018

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PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers.

21 January 2018

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ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

21 January 2018

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Epidermal growth factor receptor family in lung cancer and premalignancy

21 January 2018

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The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

21 January 2018

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The role of HER-2/neu expression on the survival of patients with lung cancer: a systematic review of the literature

21 January 2018

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Expression of c-myc in progenitor cells of the bronchopulmonary epithelium and in a large number of non-small cell lung cancers

21 January 2018

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High telomerase activity in primary lung cancers: association with increased cell proliferation rates and advanced pathologic stage.

21 January 2018

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Increased telomerase activity and elevated hTERT mRNA expression during multistage carcinogenesis of squamous cell carcinoma of the lung.

21 January 2018

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hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

21 January 2018

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Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

21 January 2018

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Telomerase suppression by chromosome 6 in a human papillomavirus type 16-immortalized keratinocyte cell line and in a cervical cancer cell line

21 January 2018

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Elevated hTERT mRNA levels: A potential determinant of bronchial squamous cell carcinoma (in situ).

21 January 2018

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Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

21 January 2018

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Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

21 January 2018

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

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Mapping of the human BAX gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, BAX delta.

21 January 2018

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bcl-2 protein in non-small-cell lung carcinoma

21 January 2018

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Expression of the BCL-2 protein in normal and dysplastic bronchial epithelium and in lung carcinomas

21 January 2018

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Role of Bcl-2 as a prognostic factor for survival in lung cancer: a systematic review of the literature with meta-analysis

21 January 2018

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A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

21 January 2018

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IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

21 January 2018

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Survivin gene expression in early-stage non-small cell lung cancer.

21 January 2018

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Expression of inhibitors of apoptosis (IAP) proteins in non-small cell human lung cancer

21 January 2018

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Cyclooxygenase regulates angiogenesis induced by colon cancer cells

21 January 2018

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Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

21 January 2018

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Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways.

21 January 2018

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Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer

21 January 2018

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Risk of cancer in a large cohort of nonaspirin NSAID users: a population-based study

21 January 2018

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A high vascular count and overexpression of vascular endothelial growth factor are associated with unfavourable prognosis in operated small cell lung carcinoma.

21 January 2018

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

21 January 2018

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Vascular endothelial growth factor and lymph node metastasis in primary lung cancer

21 January 2018

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21 January 2018

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Organ-specific molecular classification of primary lung, colon, and ovarian adenocarcinomas using gene expression profiles

21 January 2018

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Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

21 January 2018

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Diversity of gene expression in adenocarcinoma of the lung

21 January 2018

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Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs

21 January 2018

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Integrated classification of lung tumors and cell lines by expression profiling

21 January 2018

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Comparative proteomics analysis of human lung squamous carcinoma

21 January 2018

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Proteomic patterns of tumour subsets in non-small-cell lung cancer

21 January 2018

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Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancer

21 January 2018

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Human non-small cell lung cancer: P53 protein accumulation is an early event and persists during metastatic progression

21 January 2018

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Angiogenesis as a Prognostic Indicator of Survival in Non-Small-Cell Lung Carcinoma: a Prospective Study

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000085376

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12 August 2017

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PubMed ID

15942304