An ankyrinG-binding motif is necessary and sufficient for targeting Nav1.6 sodium channels to axon initial segments and nodes of Ranvier (Q36146107)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22623668%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

An ankyrinG-binding motif is necessary and sufficient for targeting Nav1.6 sodium channels to axon initial segments and nodes of Ranvier (English)

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2 February 2020

3

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2 February 2020

Kae-Jiun Chang

4

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2 February 2020

Matthew N. Rasband

6

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2 February 2020

author name string

Andreas Gasser

1

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2 February 2020

Tammy Szu-Yu Ho

2

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2 February 2020

Stephen G Waxman

5

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2 February 2020

Sulayman D Dib-Hajj

7

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2 February 2020

language of work or name

English

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publication date

1 May 2012

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2 February 2020

published in

Journal of Neuroscience

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2 February 2020

volume

32

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2 February 2020

issue

21

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2 February 2020

page(s)

7232-7243

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describes a project that uses

2 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3413458/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Schwann cell spectrins modulate peripheral nerve myelination

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Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability

2 October 2017

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Axonal sodium-channel bands shape the response to electric stimulation in retinal ganglion cells

2 October 2017

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Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G.

2 October 2017

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The Kv2.1 K+ channel targets to the axon initial segment of hippocampal and cortical neurons in culture and in situ

2 October 2017

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AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity.

2 October 2017

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2 October 2017

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The functional organization and assembly of the axon initial segment.

2 October 2017

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Neurofascin assembles a specialized extracellular matrix at the axon initial segment

2 October 2017

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Nodes of Ranvier and axon initial segments are ankyrin G-dependent domains that assemble by distinct mechanisms

2 October 2017

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Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons

2 October 2017

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Differential modulation of sodium channel Na(v)1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily

2 October 2017

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Intrinsic and extrinsic determinants of ion channel localization in neurons

2 October 2017

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Early events in node of Ranvier formation during myelination and remyelination in the PNS

2 October 2017

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Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase.

2 October 2017

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Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes

2 October 2017

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Heterophilic interactions of sodium channel beta1 subunits with axonal and glial cell adhesion molecules

2 October 2017

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Endocytotic elimination and domain-selective tethering constitute a potential mechanism of protein segregation at the axonal initial segment.

2 October 2017

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Fibroblast growth factor homologous factor 2B: association with Nav1.6 and selective colocalization at nodes of Ranvier of dorsal root axons

2 October 2017

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2 October 2017

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Identification of a Conserved Ankyrin-binding Motif in the Family of Sodium Channel α Subunits

2 October 2017

1 reference

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Structural requirements for interaction of sodium channel beta 1 subunits with ankyrin

2 October 2017

1 reference

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Developing nodes of Ranvier are defined by ankyrin-G clustering and are independent of paranodal axoglial adhesion

2 October 2017

1 reference

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Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

2 October 2017

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Sodium channel beta1 and beta3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain

2 October 2017

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Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon.

2 October 2017

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Physiological roles of axonal ankyrins in survival of premyelinated axons and localization of voltage-gated sodium channels

2 October 2017

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AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing

2 October 2017

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Mutation of a new sodium channel gene, Scn8a, in the mouse mutant ‘motor endplate disease’

2 October 2017

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Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons

2 October 2017

1 reference

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Presynaptic activity regulates Na(+) channel distribution at the axon initial segment

2 July 2018

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A sodium channel mutation linked to epilepsy increases ramp and persistent current of Nav1.3 and induces hyperexcitability in hippocampal neurons

23 September 2018

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A targeting motif involved in sodium channel clustering at the axonal initial segment.

23 September 2018

1 reference

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Sodium channel Na(v)1.6 is expressed along nonmyelinated axons and it contributes to conduction.

23 September 2018

1 reference

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Differential control of clustering of the sodium channels Na(v)1.2 and Na(v)1.6 at developing CNS nodes of Ranvier

23 September 2018

1 reference

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10.1523/JNEUROSCI.5434-11.2012

23 September 2018

Identifiers

DOI

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2 February 2020

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2 February 2020

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