Structure and aggregation mechanism of beta(2)-microglobulin (83-99) peptides studied by molecular dynamics simulations (Q36129094)

12 August 2017

Structure and aggregation mechanism of beta(2)-microglobulin (83-99) peptides studied by molecular dynamics simulations (English)

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12 August 2017

Guanghong Wei

3

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author name string

Chungwen Liang

series ordinal

1

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12 August 2017

Philippe Derreumaux

series ordinal

2

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12 August 2017

language of work or name

English

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publication date

10 August 2007

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12 August 2017

10

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inferred from page(s)

published in

Biophysical Journal

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12 August 2017

93

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12 August 2017

10

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12 August 2017

3353-3362

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describes a project that uses

12 August 2017

molecular dynamics simulation

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Computational simulations of the early steps of protein aggregation

inferred from title

cites work

1 reference

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Simulations as analytical tools to understand protein aggregation and predict amyloid conformation

2 October 2017

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Effects of solvent on the structure of the Alzheimer amyloid-beta(25-35) peptide

2 October 2017

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Protein misfolding, functional amyloid, and human disease

2 October 2017

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Recent atomic models of amyloid fibril structure

2 October 2017

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A systematic screen of beta(2)-microglobulin and insulin for amyloid-like segments

2 October 2017

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Intersheet rearrangement of polypeptides during nucleation of {beta}-sheet aggregates

2 October 2017

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Sampling the self-assembly pathways of KFFE hexamers

2 October 2017

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Domain swapping is a consequence of minimal frustration

2 October 2017

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An amyloid-forming segment of beta2-microglobulin suggests a molecular model for the fibril

2 October 2017

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2 October 2017

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Protein folding and misfolding

2 October 2017

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Rationalization of the effects of mutations on peptide and protein aggregation rates.

2 October 2017

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Topological investigation of amyloid fibrils obtained from beta2-microglobulin.

2 October 2017

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Role of the single disulphide bond of beta(2)-microglobulin in amyloidosis in vitro

2 October 2017

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Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping

2 October 2017

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A 2.6 A structure of a serpin polymer and implications for conformational disease

2 October 2017

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Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

2 October 2017

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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

2 October 2017

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Serum levels of beta 2-microglobulin as a new form of amyloid protein in patients undergoing long-term hemodialysis.

2 October 2017

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The structure of the Alzheimer amyloid beta 10-35 peptide probed through replica-exchange molecular dynamics simulations in explicit solvent.

2 July 2018

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Folding landscapes of the Alzheimer amyloid-beta(12-28) peptide.

23 September 2018

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Investigating the structural properties of amyloid-like fibrils formed in vitro from beta2-microglobulin using limited proteolysis and electrospray ionisation mass spectrometry.

23 September 2018

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Characterization of two distinct beta2-microglobulin unfolding intermediates that may lead to amyloid fibrils of different morphology.

23 September 2018

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A single disulfide bond differentiates aggregation pathways of beta2-microglobulin.

23 September 2018

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Structures of a peptide fragment of beta2-microglobulin studied by replica-exchange molecular dynamics simulations - towards the understanding of the mechanism of amyloid formation.

23 September 2018

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Elongation of ordered peptide aggregate of an amyloidogenic hexapeptide NFGAIL observed in molecular dynamics simulations with explicit solvent

23 September 2018

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Amyloid-beta fibril formation is not necessarily required for microglial activation by the peptides.

23 September 2018

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Rapid assessment of contact-dependent secondary structure propensity: relevance to amyloidogenic sequences.

23 September 2018

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Dynamics in the unfolded state of beta2-microglobulin studied by NMR.

23 September 2018

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Pathway complexity of Alzheimer's beta-amyloid Abeta16-22 peptide assembly

23 September 2018

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Oligomeric assembly of native-like precursors precedes amyloid formation by beta-2 microglobulin

23 September 2018

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Core and heterogeneity of beta2-microglobulin amyloid fibrils as revealed by H/D exchange

23 September 2018

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Beta2-microglobulin amyloidosis: insights from conservation analysis and fibril modelling by protein docking techniques

23 September 2018

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Amyloid-forming peptides from beta2-microglobulin-Insights into the mechanism of fibril formation in vitro.

23 September 2018

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Charge attraction and beta propensity are necessary for amyloid fibril formation from tetrapeptides

23 September 2018

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Structural properties of an amyloid precursor of beta(2)-microglobulin

23 September 2018

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Investigation of a peptide responsible for amyloid fibril formation of beta 2-microglobulin by achromobacter protease I.

23 September 2018

1 reference

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Beta(2)-microglobulin and its deamidated variant, N17D form amyloid fibrils with a range of morphologies in vitro

23 September 2018

1 reference

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Partially unfolded states of beta(2)-microglobulin and amyloid formation in vitro

23 September 2018

1 reference

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Beta-2-microglobulin-associated amyloidosis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2072067

Probing amyloid fibril formation of the NFGAIL peptide by computer simulations

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2072067

Coarse-grained protein molecular dynamics simulations

5 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2072067

In Silico Assembly of Alzheimer's Aβ16-22Peptide into β-Sheets

5 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2072067

Molecular Dynamics Simulations and Free Energy Analyses on the Dimer Formation of an Amyloidogenic Heptapeptide from Human β2-Microglobulin: Implication for the Protofibril Structure

5 December 2018

1 reference

12 December 2020

Structure of interacting segments in the growing amyloid fibril of beta2-microglobulin probed with IR spectroscopy

1 reference

12 December 2020

Role of the C-Terminal 28 Residues of β2-Microglobulin in Amyloid Fibril Formation

1 reference

12 December 2020

Dialysis-related amyloidosis

1 reference

12 December 2020

Use of anti-(beta2 microglobulin) mAb to study formation of amyloid fibrils

1 reference

12 December 2020

Beta-2 microglobulin in renal disease

1 reference

12 December 2020

10.1529/BIOPHYSJ.107.105585

Identifiers

DOI

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12 August 2017

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12 August 2017

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