Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions (Q36116459)

12 August 2017

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title

Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions (English)

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12 August 2017

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Teddy Kosoglou

1

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12 August 2017

Paul Statkevich

2

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12 August 2017

Amy O Johnson-Levonas

3

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12 August 2017

John F Paolini

4

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12 August 2017

Arthur J Bergman

5

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12 August 2017

Kevin B Alton

6

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12 August 2017

language of work or name

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1 January 2005

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Clinical Pharmacokinetics

12 August 2017

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12 August 2017

44

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12 August 2017

467-494

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12 August 2017

5

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https://scigraph.springernature.com/pub.10.2165/00003088-200544050-00002

12 August 2017

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cites work

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12 December 2020

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Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function

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Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil.

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The Yin and Yang of cholesteryl ester transfer protein and atherosclerosis

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Pharmacokinetic interaction between ezetimibe and lovastatin in healthy volunteers

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Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

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Pharmacodynamic interaction between the new selective cholesterol absorption inhibitor ezetimibe and simvastatin

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Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4 -hydroxyphenyl)-2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption

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Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia

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12 December 2020

Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663

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12 December 2020

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12 December 2020

Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels

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12 December 2020

Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia

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12 December 2020

A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe

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12 December 2020

Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver

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12 December 2020

Pharmacodynamic interaction between ezetimibe and rosuvastatin

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12 December 2020

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Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial).

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Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia

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MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial

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Bile acid sequestrants

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12 December 2020

Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial

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12 December 2020

Effectiveness of statin titration on low-density lipoprotein cholesterol goal attainment in patients at high risk of atherogenic events

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12 December 2020

10.2165/00003088-200544050-00002

Identifiers

DOI

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Dimensions Publication ID

12 August 2017

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