Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis (Q36107360)

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English	Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis	scientific article

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29 February 2020

Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis (English)

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29 February 2020

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29 February 2020

Christine Pirker

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29 February 2020

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29 February 2020

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29 February 2020

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Sabine Spiegl-Kreinecker

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29 February 2020

Daniela Lötsch

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29 February 2020

Magdalena Laaber

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29 February 2020

Serge Weis

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29 February 2020

Alfred Olschowski

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29 February 2020

Gerald Webersinke

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29 February 2020

Josef Pichler

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29 February 2020

publication date

13 February 2015

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29 February 2020

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29 February 2020

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29 February 2020

9

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29 February 2020

1231-1240

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29 February 2020

TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations

1 reference

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2 October 2017

TERT promoter mutations: a novel independent prognostic factor in primary glioblastomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4588753

2 October 2017

TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4588753

2 October 2017

Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma

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2 October 2017

Association between telomerase reverse transcriptase rs2736100 polymorphism and risk of glioma

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2 October 2017

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas

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2 October 2017

Recurrent epimutations activate gene body promoters in primary glioblastoma

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2 October 2017

TERT promoter mutations in cancer development

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2 October 2017

The somatic genomic landscape of glioblastoma

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2 October 2017

TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism

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2 October 2017

Telomere biology and translational research.

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2 October 2017

TERT promoter mutations in primary and secondary glioblastomas.

1 reference

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2 October 2017

Frequency of TERT promoter mutations in human cancers

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2 October 2017

Telomerase at the intersection of cancer and aging

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2 October 2017

Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4588753

2 October 2017

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4588753

2 October 2017

Prognostic significance of telomerase-associated parameters in glioblastoma: effect of patient age.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4588753

2 October 2017

Highly recurrent TERT promoter mutations in human melanoma

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2 October 2017

TERT promoter mutations in familial and sporadic melanoma

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2 October 2017

The definition of primary and secondary glioblastoma

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2 October 2017

An integrated map of genetic variation from 1,092 human genomes

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2 October 2017

Regulation of the human catalytic subunit of telomerase (hTERT).

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2 October 2017

Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial

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2 October 2017

Genetic advances in glioma: susceptibility genes and networks

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4588753

2 October 2017

O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4588753

2 October 2017

Diagnostic and prognostic markers in gliomas

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4588753

2 October 2017

Genome-wide association study identifies five susceptibility loci for glioma

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2 October 2017

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

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2 October 2017

IDH1 and IDH2 mutations in gliomas

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4588753

2 October 2017

Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc.

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2 October 2017

Protein composition of catalytically active human telomerase from immortal cells

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2 October 2017

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4588753

2 October 2017

Statistical significance for genomewide studies

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2 October 2017

Telomerase in brain tumors.

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2 October 2017

A survey of telomerase activity in human cancer

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2 October 2017

Specific association of human telomerase activity with immortal cells and cancer

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2 October 2017

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

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2 October 2017

Structure and function of telomeres

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2 July 2018

Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system.

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23 September 2018

Predictive impact of MGMT promoter methylation in glioblastoma of the elderly

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23 September 2018

Presence of alternative lengthening of telomeres mechanism in patients with glioblastoma identifies a less aggressive tumor type with longer survival.

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23 September 2018

Ets2 binding site single nucleotide polymorphism at the hTERT gene promoter--effect on telomerase expression and telomere length maintenance in non-small cell lung cancer.

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23 September 2018

Telomerase activity and hTERT mRNA expression in glial tumors.

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23 September 2018

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia

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21 October 2018

Combined analysis of TERT, EGFR, and IDH status defines distinct prognostic glioblastoma classes

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase activity in cancer: a magic bullet or a mirage?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25681309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential hTERT mRNA processing between young and older glioma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25681309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NEUONC/NOV010

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29 February 2020

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29 February 2020

1 reference

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29 February 2020

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