Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1). (Q36091906)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17301694%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1) (English)

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25 December 2019

1

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25 December 2019

L Li

4

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25 December 2019

Darryl C Zeldin

10

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25 December 2019

Douglas A Bell

8

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author name string

Frank G Bottone

2

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25 December 2019

Joseph M Krahn

3

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25 December 2019

Harvey W Mohrenweiser

5

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25 December 2019

Molly E Cook

6

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25 December 2019

Robert M Petrovich

7

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25 December 2019

Thomas E Eling

9

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25 December 2019

language of work or name

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1 February 2007

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Pharmacogenetics and Genomics

25 December 2019

published in

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25 December 2019

volume

17

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25 December 2019

issue

2

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25 December 2019

page(s)

145-160

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Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities

25 December 2019

cites work

1 reference

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2 October 2017

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2 October 2017

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2 October 2017

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Polymorphisms in PTGS1 (=COX-1) and risk of colorectal polyps

2 October 2017

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2 October 2017

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Mutations within the cyclooxygenase-1 gene in aspirin non-responders with recurrence of stroke

2 October 2017

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Multiple sequence alignment with the Clustal series of programs

2 October 2017

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Genetic variation in cyclooxygenase 1: effects on response to aspirin

2 October 2017

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Cyclooxygenase 1 (COX1) polymorphisms in African-American and Caucasian populations

2 October 2017

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Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response.

2 October 2017

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Cloning of CYP2J2 gene and identification of functional polymorphisms

2 October 2017

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Functional characterization of cyclooxygenase-2 polymorphisms.

2 October 2017

1 reference

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Structural insights into the stereochemistry of the cyclooxygenase reaction

2 October 2017

1 reference

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Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products

2 October 2017

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The cyclooxygenase isoforms: structural insights into the conversion of arachidonic acid to prostaglandins

2 October 2017

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A DNA polymorphism discovery resource for research on human genetic variation

2 October 2017

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Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2

2 October 2017

1 reference

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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

2 October 2017

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Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.

2 October 2017

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Characterization of the promoter of human prostaglandin H synthase-1 gene

2 October 2017

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The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

2 October 2017

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Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system

2 October 2017

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Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme

2 October 2017

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Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase

2 October 2017

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Tyrosine 385 of prostaglandin endoperoxide synthase is required for cyclooxygenase catalysis

27 July 2018

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Marked interindividual variability in the response to selective inhibitors of cyclooxygenase-2.

27 July 2018

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Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6).

23 September 2018

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A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and stroke

23 September 2018

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Polymorphisms in human soluble epoxide hydrolase.

23 September 2018

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Characterization of the human prostaglandin H synthase 1 gene (PTGS1): exclusion by genetic linkage analysis as a second modifier gene in familial thrombosis.

23 September 2018

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Dual function of nonsteroidal anti-inflammatory drugs (NSAIDs): inhibition of cyclooxygenase and induction of NSAID-activated gene

23 September 2018

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Prostaglandin endoperoxide H synthase-1: the functions of cyclooxygenase active site residues in the binding, positioning, and oxygenation of arachidonic acid

23 September 2018

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TRANSFAC retrieval program: a network model database of eukaryotic transcription regulating sequences and proteins.

23 September 2018

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Genetically mediated interindividual variation in analgesic responses to cyclooxygenase inhibitory drugs

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17301694

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1097/01.FPC.0000236340.87540.E3

1 reference

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25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17301694%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

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